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Global warming will unquestionably increase the impact of heat on individuals who work in already hot workplaces in hot climate areas. The increasing prevalence of this environmental health risk requires the improvement of assessment methods linked to meteorological data. Such new methods will help to reveal the size of the problem and design appropriate interventions at individual, workplace and
The genomes of Asgard Archaea, a novel archaeal proposed superphylum, share an enriched repertoire of eukaryotic signature genes and thus promise to provide insights into early eukaryote evolution. However, the distribution, metabolisms, cellular structures, and ecology of the members within this superphylum are not well understood. Here we provide a meta-analysis of the environmental distribution
Background: Factor VIII (FVIII) trough levels > 1 IU/dL in patients with severe hemophilia A receiving regular prophylaxis may optimize bleed protection. Objectives: In this post hoc analysis of patients receiving tertiary prophylaxis for approximately 1 year, the relationship between estimated FVIII levels and reported bleeds was investigated to predict the potential for zero bleeds. Methods: Six
Social deprivation and marginalization in urban areas are hardships that are not necessarily limited to developing countries. Around 80 million Europeans today live in conditions that fall within the definition of poverty. However, certain areas are more prone to affliction than others. Such estates usually consist of concrete slab high-rise buildings and are often characterized by high levels of
BACKGROUND: Autistic-like traits (ALTs), that is restrictions in intuitive social interaction, communication and flexibility of interests and behaviors, were studied in two population-based Swedish twin studies, one in children and one in adults: (1) to examine whether the variability in ALTs is a meaningful risk factor for concomitant attention deficit hyperactivity disorder (ADHD), anxiety, cond
BACKGROUND: Treatment with intravenous immunoglobulin (IVIG) in children with Paediatric Acute-onset Neuropsychiatric Syndrome (PANS) has for many years been used on clinical indications, but the research evidence for its efficacy is insufficient.METHODS: Open-label prospective in-depth trial including ten children (median age 10.3 years) with PANS, who received IVIG treatment 2 g/kg monthly for t
The influence of climate on soil microorganisms governs the input and output fluxes of carbon (C) from soils. The study of the drastic responses to drying-rewetting offers an opportunity to assess an aspect of ‘soil health’ via evaluating the role of microbes in soil biochemistry and C cycling. Recent evidence has consistently shown that communities exposed to extreme moisture fluctuations recurre
Objective: This study evaluates whether food intake affects systolic and diastolic echocardiographic measurements in healthy seniors. Methods: Thirty healthy subjects 65–70 years of age were investigated with echocardiography, at fasting and then 30, 90, and 180 min after a meal. Results: After 30 min the biggest changes were seen in left ventricular wall stress and myocardial performance index wi
Background: Strenuous exercise has been associated with functional and structural cardiac changes due to local and systemic inflammatory responses, reflecting oxidative, metabolic, hormonal, and thermal stress, even in healthy individuals. We aimed to assess changes in myocardial structure and function using cardiovascular magnetic resonance (CMR) imaging in master triathletes early after a full-d
Gram-negative bacteria from the genus Acinetobacter are responsible for life-threating hospital-related infections such as pneumonia, septicemia, and meningitis, especially in immunocompromised patients. Worryingly, Acinetobacter have become multi- and extensively drug resistant (MDR/XDR) over the last few decades. The complement system is the first line of defense against microbes, thus it is hig
BACKGROUND: Covid-19 transmission via exhaled aerosol particles has been considered an important route for the spread of infection, especially during super-spreading events involving loud talking or singing. However, no study has previously linked measurements of viral aerosol emissions to transmission rates.METHODS: During Feb-Mar 2021, covid-19 cases that were close to symptom onset were visited
Background: Learning is a lifelong process and the workplace is an essential arena for professional learning. Workplace learning is particularly relevant for midwives as essential knowledge and skills are gained through clinical work. A clinical practice known as ‘Collegial Midwifery Assistance’ (CMA), which involves two midwives being present during the active second stage of labour, was found to
Introduction: Carbon monoxide (CO) is a colorless and odorless gas that is a leading cause of environmental poisoning in the USA with substantial mortality and morbidity. The mechanism of CO poisoning is complex and includes hypoxia, inflammation, and leukocyte sequestration in brain microvessel segments leading to increased reactive oxygen species. Another important pathway is the effects of CO o
Background: Acute kidney injury (AKI) is a serious complication following major surgery. This study examined the incidence and risk factors of AKI following orthopaedic surgeries in an Icelandic cohort, as well as the association between AKI and patient- and surgery-related factors. Methods: This retrospective cohort study comprised all patients 18 years and older who underwent orthopaedic surgeri
In the year 2000, the alcohol habits of 1460 Swedish university students living in residence halls were assessed. The students had a mean age of 23.8 years, and 64% were male. The results from this baseline assessment show that the mean AUDIT score (± sd) was 10.3 ± 5.2 for males and 8.1 ± 4.7 for females. AUDIT stands for Alcohol Use Disorders Identification Test and is used world-wide to assess
Modelers seeking to help inform decisions about insurance (public or private) coverage of the cost of pharmaceuticals or other health care interventions face various methodological challenges. In this review, which is not meant to be comprehensive, we cover those that in our experience are most vexing. The biggest challenge is getting decision makers to trust the model. This is a major problem bec
The study is based upon material which is a part of the Swedish Agency for Education's evaluation of oral production in year five at primary school. The overall aim of this study is to examine w h a t is assessed by describing the childrens speech, developing and testing criteria for the proficiency in speech in relation to this assessment. For qualitative purposes, a description of the phenomenon
Objectives To develop normal reference ranges for cervical volume and vascular indices using three-dimensional (3D) power Doppler ultrasonograpby from 17 to 41 gestational weeks. Methods This was a cross-sectional study of 352 nulliparous and 291 parous women who delivered at term and underwent transvaginal 3D power Doppler ultrasound examination of the cervix once at 17 to 41 weeks' gestation. We
Aim We explored regional variations in the surgical management of patients with Dupuytren's contracture (DC) in 12 European countries using a surgeon survey and patient chart review. Methods Twelve countries participated: Denmark, Finland, Sweden (Nordic region); Czech Republic, Hungary, Poland (East); France, Germany, the Netherlands, UK (West); Italy, Spain (Mediterranean). For the survey, a ran
För att öka vår förståelse av informationsdelning i försörjningskedjor så är studiens syfte trefaldigt: att granska och analysera existerande akademisk litteratur för att beskriva och strukturera forskningsområdet; att empiriskt utforska informationsdelning i en försörjningskedja som representerar mer än tre led; och att utforska kontextuella faktorer genom litteraturgenomgång och empirisk datainsTo increase our understanding of information sharing in supply chains the purposeof this licentiate was threefold: to review and analyze existing academic literature to describe and structure the research field; to empirically explore information sharing in a supply chain representing more than three tiers; and to explore contingency factors through literature reviews and empirical data collection
