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On the complexity of screening detected abdominal aortic aneurysms : A retrospective observational multicenter cohort study

BACKGROUND: Ultrasound screening for abdominal aortic aneurysms (AAA) has been shown to decrease aneurysm related mortality. Likely by providing an opportunity to intervene while the aneurysm is still intact, but possibly also when and the anatomy still relatively uncomplicated which would provide a less complex procedure. Our aim was to retrospectively investigate the complexity of repair for scr

Joint Infection Rates After and before A National Infection Control Program : A Study of 45,438 Primary Total Knee Arthroplasties

Background and purpose — Strenuous efforts to minimize postoperative infection rates have been made, including the Swedish nationwide initiative Prosthesis Related Infections Shall be Stopped (PRISS). This study calculated the incidence rate of periprosthetic joint infection (PJI) following primary total knee arthroplasty (TKA) before and after PRISS. Patients and methods — All 45,438 primary TKAs

Pretreatment with heparin in patients with ST-segment elevation myocardial infarction : a report from the Swedish Coronary Angiography and Angioplasty Registry (SCAAR)

Background: Unfractionated heparin (UFH) is frequently administered before percutaneous coronary intervention (PCI) in patients with ST-segment elevation myocardial infarction (STEMI). Aims: The aim of the study was to investigate if pretreatment with UFH prior to arrival at the catheterisation laboratory affects coronary artery occlusion, mortality, and in-hospital major bleeding in patients with

LeucoPatch system for the management of hard-to-heal diabetic foot ulcers in the UK, Denmark, and Sweden : an observer-masked, randomised controlled trial

METHODS: This was a multicentre, international, observer-masked, randomised controlled trial of people with diabetes and a hard-to-heal foot ulcer done in 32 specialist diabetic foot clinics in three countries (UK, Denmark, and Sweden). After a 4-week run-in period, those with a reduction in ulcer area of less than 50% were randomly allocated (1:1) by computer-generated, web-based randomisation (b

Assessing wastewater processes at oil refinery industry in Kazakhstan

This paper presents the first attempt to assess the wastewater treatment processes at the oil refinery sector in Kazakhstan and evaluate to what extent these processes follow international and national regulations regarding industrial waste water treatment. The assessment was performed considering wastewater discharge from refining processes at three factories in the country. While Kazakhstani env

First line therapy in chronic lymphocytic leukemia : a Swedish nation-wide real-world study on 1053 consecutive patients treated between 2007 and 2013

The aim of this study was to investigate long-term outcome following first line therapy in consecutive chronic lymphocytic leukemia patients in a well defined geographic area (Sweden). All patients diagnosed with chronic lymphocytic leukemia (2007-2013) (n=3672) were identified from national registries, screening of patient files identified all (100%) first line treated (n=1053) and for those, dep

Prospective population-based cohort study of maternal obesity as a source of error in gestational age estimation at 11–14 weeks

Introduction: An impact of maternal obesity on ultrasound dating of pregnancy at 11–14 gestational weeks is possible and was investigated. Material and methods: A prospective cohort study based on the Danish national population during a 4-year period in which we entered all mothers with singleton pregnancies who had a known last menstrual period (LMP), a recorded booking of body mass index (BMI),

Mortality among amphetamine users with hepatitis C virus infection : A nationwide study

Aims To investigate liver-related and all-cause mortality among amphetamine users with hepatitis C virus (HCV) infection and compare this with opioid users with HCV infection and the uninfected general population. Methods In this national register study of mortality in persons notified with HCV infection 1990–2015 and a substance-related diagnosis in Sweden, amphetamine users (n = 6,509) were comp

Dynamics of Selected Biomarkers in Cerebrospinal Fluid During Complex Endovascular Aortic Repair – A Pilot Study

Introduction: Ischemic spinal cord injury (SCI) is a serious complication of complex aortic repair. Prophylactic cerebrospinal fluid (CSF) drainage, used to decrease lumbar cerebrospinal fluid (CSF) pressure, enables monitoring of CSF biomarkers that may aid in detecting impending SCI. We hypothesized that biomarkers, previously evaluated in traumatic SCI and brain injury, would be altered in CSF

Statin Treatment Intensity, Discontinuation, and Long-Term Outcome in Patients with Acute Myocardial Infarction and Impaired Kidney Function

Statin dosage in patients with acute myocardial infarction (AMI) and concomitant kidney dysfunction is a clinical dilemma. We studied discontinuation during the first year after an AMI and long-term outcome in patients receiving high versus low-moderate intensity statin treatment, in relation to kidney function. For the intention-to-treat analysis (ITT-A), we included all patients admitted to Swed

Mortality not increased in patients with non-functional adrenal adenomas : a matched cohort study

CONTEXT: Mild autonomous cortisol secretion (MACS) is associated with increased mortality in patients with adrenal incidentalomas (AI), but little is known regarding the potential risk associated with non-functional adrenal adenomas (NFAA), which constitute the majority of AI.OBJECTIVE: Compare mortality risk in patients with NFAA, and different levels of MACS, to matched controls.METHOD: This was

Risk and outcomes of COVID-19 in patients with oxygen-dependent chronic respiratory failure– a national cohort study

Background: We aimed to evaluate cumulative occurrence and impact of COVID-19 in patients with chronic respiratory failure (CRF) treated with long-term oxygen therapy (LTOT). Material and methods: Data were obtained from the SCIFI-PEARL study on the entire Swedish population and on patients with oxygen-dependent CRF and no COVID-19 diagnosis before start of LTOT. Analyses were performed for three

Daily duration of long-term oxygen therapy and risk of hospitalization in oxygen-dependent COPD patients

Introduction: Long-term oxygen therapy (LTOT) improves survival and may reduce hospital admissions in patients with chronic obstructive pulmonary disease (COPD) and severe hypoxemia, but the impact of daily duration of LTOT on hospitalization rate is unknown. We aimed to estimate the association between the daily duration of LTOT (24 vs 15 h/d) and hospital admissions in patients with LTOT due to

Long-term oxygen therapy 24 vs 15 h/day and mortality in chronic obstructive pulmonary disease

Long-term oxygen therapy (LTOT) ≥ 15 h/day improves survival in hypoxemic chronic obstructive pulmonary disease (COPD). LTOT 24 h/day is often recommended but may pose an unnecessary burden with no clear survival benefit compared with LTOT 15 h/day. The aim was to test the hypothesis that LTOT 24 h/day decreases all-cause, respiratory, and cardiovascular mortality compared to LTOT 15 h/day in hypo

Ozonering och biologisk nedbrytning av isotopmärkta mikroföroreningar i avloppsvatten

Implementation av ozonering som teknik på avloppsreningsverk är en av de lösningar som har visat sig effektiv för att avlägsna läkemedelsrester och andra mikroföroreningar och förhindra att de hamnar i naturliga vattendrag. Uppkomsten av transformationsprodukter till följd av ozonering och hur väl ett efterföljande biologiskt reningssteg kan ta hand omdem ett område där mer kunskap behövs. I dettaThe implementation of ozonation technology in sewage treatment plants is a solution that has proven efficient in removing residual pharmaceutical substances and other micropollutants to prevent their spreading in natural water bodies. The appearance of transformation products originating from micropollutants as a result of ozonation, and how well biological post treatment can remove these is a res

Factors associated with adverse treatment outcomes of Tuberculosis among HIV-positive adults in an antiretroviral treatment program in Yangon, Myanmar

Introduction: Tuberculosis (TB) is the most common opportunistic infection (OI) and cause of death in people living with HIV/AIDS (PLHIV), even in settings with access to antiretroviral therapy (ART). This study aims to determine factors associated with adverse outcome of TB treatment in PLHIV. Materials and Method: The study was retrospective cohort study which includes 958 individuals aged ≥15 y

Impact of security context on mobile clinic activities : a GIS multi criteria evaluation based on an MSF humanitarian mission in Cameroon

Humanitarian crises require a quick and effective emergency response to answer the needs of vulnerable populations. Deploying mobile health clinics in the field is an example of an outreach activity that can be undertaken for this purpose. This study is based on a real mission implemented by a medical international aid organization (MSF or Médecins Sans Frontières) in Cameroon during the recent Ce

Understanding the role of the co-chaperone Auxilin in α -synuclein aggregation

Can co-chaperone proteins help against Parkinson’s Disease ? Our cells have assigned proteins called ‘chaperone’ and their helper ‘co-chaperone proteins that work extensively to regulate and maintain the protein structure in our cells. However, proteins like α-synuclein manage to clump together in nerve cells and are believed to acquire toxic characteristics that contribute to the death and damag

The Impact of Digitalization on Sales and Operations Planning and Its Influence on Supply Chain Performance

This research examines the impact of digitalization on Sales and Operations Planning (S&OP) and its broader influence on supply chain performance. By adopting digital technologies, companies can streamline decision-making processes, reduce manual efforts, and enhance operational efficiency. The study aims to address the insufficient understanding of how the integration of digital technologies Impact of Digitalization on Sales and Operations Planning and Its Influence on Supply Chain Performance By Ali Mustafa Ali Ishag and Qiong María García Calatayud (2024) Imagine an orchestra playing with different music sheets—chaos, right? Now, imagine they have the same sheet, but the composer's handwriting is nearly illegible. How would they perform? Would a typed sheet work better? Then

The Search for Synergies - An exploration of differences in challenges and opportunities in managing sustainable activities across developed and emerging markets

Title: The Search for Synergies - An exploration of differences in challenges and opportunities in managing sustainable activities across developed and emerging markets Seminar Date: 2024-05-30 Course: BUSN09, Degree project in International Strategic Management Authors: Adam Fornell and Clarissa Nadya Supervisor: Magnus Johansson Keywords: Multinational Corporations, Sustainable Valu