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Differential modulation of caffeine- and IP3-induced calcium release in cultured arterial tissue

To investigate the Ca2+-dependent plasticity of sarcoplasmic reticulum (SR) function in vascular smooth muscle, transient responses to agents releasing intracellular Ca2+ by either ryanodine (caffeine) or D-myo-inositol 1,4,5-trisphosphate [IP3; produced in response to norepinephrine (NE), 5-hydroxytryptamine (5-HT), arginine vasopressin (AVP)] receptors in rat tail arterial rings were evaluated a

Different clinical expressions in two families with Stargardt's macular dystrophy (STGD1)

Purpose: To describe the clinical expressions, with emphasis on electrophysiological examinations, in two Swedish families with Stargardt's macular dystrophy (STGD1). Methods. Two pairs of siblings with STGD1, for whom diagnosis had been confirmed by genetic linkage to the ABCA4 gene region, were examined regarding visual acuity, kinetic perimetry, fundus photography, full-field ERG and multifocal

The pioneer gut microbiota in human neonates vaginally born at term - a pilot study.

The pioneer microbiota of the neonate may affect future actions of the immune system. This study aimed to map the pioneer microbiota in healthy neonates vaginally born at term. A subgroup of neonates born large for gestational age (LGA) was compared with the neonates appropriate for gestational age (AGA). Fecal samples were collected, within 48 hours after birth, from 79 neonates. Quantitative pol

Changes in phenolic antioxidants during chuno production (traditional Andean freeze and sun-dried potato)

Total antioxidant capacity (TAC), total phenolic compounds (TPH), total flavonoids (TF) and the amounts of individual phenolic compounds were assessed in Bolivian potato cultivars (various Solanum species) before, during and after the traditional freezing and sun-drying of potatoes known as chunos. The TAC of chunos ranged from 0.4 to 2.7 mu mol Trolox equivalents/g dry matter using 2,2'-azino-bis

High-speed biomarker identification utilizing porous silicon nanovial arrays and MALDI-TOF mass spectrometry

Speed and accuracy are crucial prerequisites in the application of proteomic methods to clinical medicine. We describe a microfluidic-based nanovial array for rapid proteolytic processing linked to MALDI-TOF MS. This microscale format consumes only minute amounts of sample, and it is compatible with rapid bioanalytical protocols and high-sensitivity readouts. Arrays of vials (300 mu m in diameter

Genetic mapping at 3-kilobase resolution reveals inositol 1,4,5-triphosphate receptor 3 as a risk factor for type 1 diabetes in Sweden.

We mapped the genetic influences for type 1 diabetes (T1D), using 2,360 single-nucleotide polymorphism (SNP) markers in the 4.4-Mb human major histocompatibility complex (MHC) locus and the adjacent 493 kb centromeric to the MHC, initially in a survey of 363 Swedish T1D cases and controls. We confirmed prior studies showing association with T1D in the MHC, most significantly near HLA-DR/DQ. In the

Influence of the alkali metal salt on the properties of solid electrolytes derived from a Lewis acidic polyether

A polyether containing Lewis acidic boron atoms in its branched chain architecture was synthesised by a condensation reaction of boron trioxide, triethylene glycol monomethyl ether and poly(ethylene glycol), the latter having a molecular weight of 300 g/mol. Electrolytes based on this polymer and several different alkali metal salts were prepared and investigated. The state of the ions in the elec

A new cyclodextrin glycosyltransferase from an alkaliphilic Bacillus agaradhaerens isolate: purification and characterisation

A new, cyclodextrin glycosyltransferase (CGTase) from an alkaliphilic B. agaradhaerens strain LS-3C, isolated front an Ethiopian soda lake. was purified up to 43-fold by starch adsorption with a yield of 50%. The enzyme was a monomer with an estimated molecular weight of 110 kDa, representing the largest Bacillus CGTase reported so far. The isoelectric point (pI) of the enzyme was 6.9. The CGTase

Tissue and intracellular pH in normal periarticular soft tissue and during different phases of antigen induced arthritis in the rat

OBJECTIVE: To measure intracellular and tissue pH in periarticular soft tissue during different phases of antigen induced arthritis in the rat. METHODS: pH was calculated using the following values: (1) the distribution of [14C]-dimethyl-oxazolidinedione; (2) the total tissue water and the extracellular space water volume, which was measured as [14C]-sucrose distribution in nephrectomized rats. Ex

Description of ParaSol v3.0 and comparison with measurements

Parasol is a computer program for calculating the solar and thermal properties of windows with sunshades and the energy demands of a room with a window/shading system. The program has three main features. One of them is a calculation of g, T and U for normal incidence of beam irradiation, which is performed as soon as a window or an internal/interpane sunshade is selected. The other two are based

Photoelectrochemical investigation of methylene blue immobilised on zirconium phosphate modified carbon paste electrode in flow injection system

The adsorption of methylene blue (MB) onto zirconium phosphate (ZrP) was studied and the adsorption capacity value and isotherms were determined. The adsorption capacity of ZrP was increased after being exposed to gas phase n-butyl amine. The adsorbed MB on ZrP was used as a modifier material in carbon paste electrode (MCPE), which in turn was used in voltammetric investigations and flow injection

The expression of lymphocyte surface antigens in bronchial biopsies, bronchoalveolar lavage cells and blood cells in healthy smoking and never-smoking men, 60 years old

In this study we investigated if smoking subjects with a normal or slightly decreased lung function differ in the lymphocyte pattern compared to never-smokers. In a group of 'healthy' smokers (n = 58) and never-smokers (n = 34) 60 years old, we investigated the lymphocyte pattern in both BAL (n = 30 and n = 18 respectively), bronchial epithelium and lamina propria (n = 14 and n = 10 respectively)

Enhancement of Y-D(center dot) spin relaxation by the CaMn4 cluster in photosystem II detected at room temperature: A new probe for the S-cycle

The long-lived, light-induced radical Y-D(.) of the Tyr161 residue in the D2 protein of Photosystem 11 (PSII) is known to magnetically interact with the CaMn4 cluster, situated similar to 30 angstrom away. In this study we report a transient step-change increase in YD EPR intensity upon the application of a single laser flash to S, state-synchronised PSII-enriched membranes from spinach. This tran

A 20-GHz Bandwidth Power Amplifier for Phased Array 5G New Radio Transmitters

A 27-47-GHz differential cascode power amplifier for millimeter-wave 5G new radio applications is presented. The PA is a three-stage design using inductively coupled impedance transformers with 31-dB nominal power gain. A device periphery ratio of 1:2:6 is adopted for predriver, driver, and final stage, respectively. A gain equalization technique was used in the interstage transformers to obtain t

Web overturism nr5

Vad är överturism? En kunskapsöversikt CECILIA CASSINGER OCH JAN HENRIK NILSSON SAMHÄLLSVETENSKAPLIG FAKULTETEN | LUNDS UNIVERSITET 2 VAD ÄR ÖVERTURISM? Omslagsbild: Elizeu Dias on Unsplash Copyright: Cecilia Cassinger och Jan Henrik Nilsson Samhällsvetenskaplig fakulteten | Institutionen för strategisk kommunikation och Institutionen för service management och tjänstevetenskap | Lunds universitet

https://www.isk.lu.se/sites/isk.lu.se/files/web_overturism_nr5.pdf - 2026-05-03

On the right track? Energy use, carbon emissions, and intensities of world rail transportation, 1840–2020

The history of rail transport can offer valuable insights for future energy transitions due to its importance in promoting clean mobility. There is a complex interplay between the evolution of the railway network, fuel consumption, efficiency, energy service, and CO2 emissions that requires further exploration. We developed a dataset that covers energy use in all stages of rail transportation, as

Grönytefaktor i praktiken

Dagens stadsbyggnadsprojekt är komplexa och många funktioner ska trängas på en liten yta i våra städer. I ett försök att ge grönstruktur i städer större plats har flera kommuner runt om i landet börjat ställa krav kring grönytefaktor; ett sätt att mäta mängden grönska på tomter i staden. I denna studie undersöktes vilken effekt detta krav har på samhällsbyggandet och hur det fungerar i samspelet mAbstract Title: Green Area Factor in affect – How does the implementation of Green Area Factor requirements work in Sweden today? Author: Johanna Hallberg Supervisors: Anne Landin – Professor, Department of Construction Management, Lund University Dagmar Gormsen – Social development leader at Sustainable Business Development at Skanska Sweden AB Examiner: Stefan Olander – Docent, Department of C

China’s Strategic Narratives in Italy – A study on Online Promotions between Official and Unofficial Sources

Public diplomacy, public relations, propaganda, and strategic narratives are all under the ‘umbrella’ of soft-power and nowadays’ international relations. Strategic narratives currently represent one of the most essential tools that political actors use to increase their influence on local and foreign audiences, gain public support, and lastly achieve their foreign policy objectives. This disser

Synthesis of Linear Fused Tröger’s Base Analogues

Tröger’s base molecule has a unique V-shaped cavity and a chiral structure. These molecules can be fused together in a linear fashion to create either tubular structure or zigzag structure. Different fields can be benefited from the applications of these molecules. Previous studies carried out in the Wärnmark group led to 30-step synthesis route to get a linearly fused heptakis-Tröger’s Base anal