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The need for more functionality and higher performance has increased the number of transistors to billions in current processors. A high number of transistors on the same chip area increases the power density, which in turn heats up the devices and lowers the life time of batteries. The increasing demand for devices relying on battery and harvested energies in the Internet of Things (IoT) era has
Background: Working conditions substantially influence health, work ability and sick leave. Useful instruments to help clinicians pay attention to working conditions are lacking in primary care (PC). The aim of this study was to test the validity of a short "Blue flags" questionnaire, which focuses on work-related psychosocial risk factors and any potential need for contacts and/or actions at the
That data from polar orbiting satellites have detected a widespread increase in photosynthetic activity over the last 20 years in the grasslands of the Sahel is justifies investigating its role in the tropical carbon cycle. But this task is undermined because ground data that are generally used to support the use of primary production models elsewhere are lacking. In this paper, we profile a Light
Every year, 100,000 tons of dissolved hemicelluloses are discharge unused with wastewater from thermomechanical pulp mills around the world. Isolation of these hemicelluloses from the wastewater would not only reduce the treatment costs for the pulp mills but would also provide an excellent raw material for high value applications such as oxygen barriers in food packaging. The isolation of the he
We present the results of 3D high-resolution calculations of the last inspiral stages and the final coalescence of neutron star binary systems. The equations of hydrodynamics are solved using the smoothed particle hydrodynamics method with up to 106 particles. Using Newtonian gravity, but adding the forces emerging from the emission of gravitational waves, we focus on the impact of microphysics on
This doctoral dissertation presents the development and digital hardware realization of cardiac event detectors. Implantable medical appliances, as the cardiac pacemaker, have progressed from a life sustaining device to a device that considerably improves life quality for all ages. The number of electronic devices and household appliances in everyday live has an ongoing exponential growth. The
Somatostatin receptor positron emission tomography with computerised tomography imaging (SRI) has a high sensitivity for the detection of small intestinal neuroendocrine tumors (siNET), which makes it ideal for follow-up. The aim of the present study was to investigate whether follow-up with SRI in patients with siNET led to any change in the treatment of the patient and if patient and/or tumour f
Background: The burden of Parkinson’s disease (PD) worsens with disease progression. However, the lack of objective and uniform disease classification challenges our understanding of the incremental burden in patients with advanced Parkinson’s disease (APD) and suboptimal medication control. The 5–2-1 criteria was proposed by clinical consensus to identify patients with advancing PD. Our objective
Popular Abstract in Swedish Gastroesofageal refluxsjukdom innebär att maginnehåll backar (reflux) upp från magsäcken till matstrupen på ett onormalt sätt. Hos den friska individen finns flera mekanismer som skyddar matstrupen från reflux, vilket tydligt åskådliggörs av att man efter en måltid kan ställa sig upp och ner utan att föda backar upp i matstrupen. Vid refluxsjukdom föreligger defekter inEsophageal pH monitoring is important in the clinical management of patients with symptoms suggestive of gastroesophageal reflux disease (GERD), and in research aiming to clarify the mechanisms involved in the development of GERD complications. Catheter-based techniques for pH recording are uncomfortable, not well tolerated by all patients and cannot reliably measure acid exposure in the most dist
1.Intraguild predation (IGP) is a commonly recognised mechanism influencing the community structure of predators, but the complex interactions are notoriously difficult to disentangle. The mesopredator suppression hypothesis predicts that a superpredator may either simultaneously repress two mesopredators, restrain the dominant one and thereby release the subdominant mesopredator, or elicit differ
High testosterone levels have been associated with breast cancer. BRCA1 may function as an androgen receptor (AR) co-regulator. We aimed to examine AR haplotype-tagging single-nucleotide polymorphisms (AR htSNPs) and diplotypes in relation to in vivo androgen levels, combined OC use, CAG and GGC genotypes, and BRCA1/2/X family status in 269 young healthy women from breast cancer high-risk families
Cerebral accumulation of amyloid-β is thought to be the starting mechanism in Alzheimer's disease. Amyloid-β can be detected by analysis of cerebrospinal fluid amyloid-β42 or amyloid positron emission tomography, but it is unknown if any of the methods can identify an abnormal amyloid accumulation prior to the other. Our aim was to determine whether cerebrospinal fluid amyloid-β42 change before am
The overall aim of this thesis is to examine how walking as a transport mode is constructed in the planning realm, affected by the built environment and perceived by the individual. This aim is related to the following research questions: (1) How are pedestrians and walking understood, constructed and perceived in the planning context? (2) How does individual traits and the built environment affec
Background: Repolarization prolongation can be the earliest electrophysiological change in ischemia, but its role in arrhythmogenesis is unclear. The aim of the present study was to evaluate the early ischemic action potential duration (APD) prolongation concerning its causes, expression in ECG and association with early ischemic ventricular fibrillation (phase 1A VF). Methods: Coronary occlusion
High-order harmonic generation (HHG) is a highly nonlinear optical process in which extreme ultraviolet (XUV) radiation is generated due to the interaction of an intense laser field with atoms. This process enables the production of high harmonics, which would not be achieved with standard nonlinear media. The utilization of two-color laser fields (formed by combining a fundamental field with one
With an increased importance of working capital management and supply chain risks, supply chain finance has gained an increasing interest from organizations across the world. A buyer-centric supply chain finance solution can create a ‘win-win’ situation for buyers and suppliers, by allowing buyers to extend payment terms and suppliers to get payments in advance. This allows both buyers and supplie
To examine nanoparticle toxicity there is a need to produce defined nanoparticles dispersed in a colloidal suspension. Such a solution could also be interesting for other fields such as nano-medicine. In order to disperse the particles in the liquid there are often surfactant added to the process that alternates the surface of the particles. As the research shows that the surface of a nanoparticle
The overall aim of the thesis is to investigate the knowledge problem in regional public transport planning. The knowledge problem is twofold. How do transport policy arrive at the desirable actions they take and how do they assess the alternatives, and what can we say about the contributions of already implemented transport schemes. Paper 1 explores how policy objectives in regional public transp
In insects airborne odors are detected by the odorant receptors (ORs) and ionotropic receptors (IRs), located on the dendritic membrane of the olfactory sensory neurons (OSNs) housed in olfactory sensilla. The OR and IR gene families show high plasticity in lineage expansion and contraction following the birth-and-death evolutionary model. Gene duplication is an important mechanism underlying the
