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Birthweight and risk of chronic kidney disease after a type 2 diabetes diagnosis in the DD2 cohort

Aims/hypothesis: Low birthweight (LBW) is associated with younger age, less obesity and more hypertension among people recently diagnosed with type 2 diabetes, as well as increased cardiovascular morbidity and mortality risk. It is not known whether LBW is associated with an increased risk of incident chronic kidney disease (CKD) among people with a type 2 diabetes diagnosis. Methods: Original mid

Sertoli and Germ Cells Within Atrophic Seminiferous Tubules of Men With Non-Obstructive Azoospermia

Background: Infertile men with non-obstructive azoospermia (NOA) have impaired spermatogenesis. Dilated and un-dilated atrophic seminiferous tubules are often present in the testes of these patients, with the highest likelihood of active spermatogenesis in the dilated tubules. Little is known about the un-dilated tubules, which in NOA patients constitute the majority. To advance therapeutic strate

An experimental study of the flow around a circular cylinder: Influence of aspect ratio

The investigation is concentrated on two important quantities – the Strouhal number and the mean base suction coefficient, both measured at the mid-span position. Reynolds numbers from about 50 to 4 × 104 were investigated. Different aspect ratios, at low blockage ratios, were achieved by varying the distance between circular end plates (end plate diameter ratios between 10 and 30). It was not pos

Washing machine ownership and girls' school attendance : a cross-sectional analysis of adolescents in 19 middle-income countries

Excessive work among adolescents may compromise educational development. Without home appliances, household work can take over 50 h a week and an additional 30 h when an infant is present. School-aged girls are often tasked with doing laundry, which is time-consuming and inflexible without a washing machine. We determined the association between washing machine ownership and school attendance amon

Definition of landscape erosion units using a structural classification OASIS of Landsat TM satellite imageries, case study Lebanon.

Soil erosion by water is a major cause of landscape degradation in semi-humid to semi-arid Mediterranean environments. Terrain particularly susceptible to the phenomenon witness a combination of erosive soil, unconsolidated rock type, steep slope, high rainfall intensity, active tectonic movement, rapid land use change and intense human interference. Current erosion models (e.g. USLE, RUSLE) are b

Suppression of limbic motor seizures by electrical stimulation in thalamic reticular nucleus

Kindling is a model of temporal lobe epilepsy in which repeated electrical stimulations in limbic areas lead to progressive increase of seizure susceptibility, culminating in generalized convulsions and the establishment of a permanent epileptic syndrome. We studied here the effect of stimulations in the thalamic reticular nucleus (TRN) on. the development of seizures and hippocampal hyperexcitabi

Distribution of MR-detected cartilage defects of the patellofemoral joint in chronic knee pain

Objectives: The aim of the study was to detect cartilage defects and determine the center of these defects in MR imaging of the patellofemoral joint (PFJ) in middle-aged people with chronic knee pain. Design: In the format of a prospective study of early osteoarthritis (OA), this cross-sectional study of the signal knee (the most painful one at inclusion in the study in 1990) in 59 individuals, 30

Synthesis of Linear Fused Tröger’s Base Analogues

Tröger’s base molecule has a unique V-shaped cavity and a chiral structure. These molecules can be fused together in a linear fashion to create either tubular structure or zigzag structure. Different fields can be benefited from the applications of these molecules. Previous studies carried out in the Wärnmark group led to 30-step synthesis route to get a linearly fused heptakis-Tröger’s Base anal

Exploring the interplay of fungi and bacteria in vaginal microbiota

What does Candida have in common with vaginal microbiota? We share our body with millions of microbes, which share a common space and interact tightly. All the interactions between them are important for keeping a good microenvironment. However, there is always a disruption of what should be otherwise a comfortable place to live. Such changes can be subtle or can affect entire communities of micr

Hydrogen intercalation of graphene grown on 6H-SiC(0001)

Atomic hydrogen exposures on a monolayer graphene grown on the SiC(0001) surface are shown to result in hydrogen intercalation. The hydrogen intercalation induces a transformation of the monolayer graphene and the carbon buffer layer to bi-layer graphene without a buffer layer. The STM, LEED, and core-level photoelectron spectroscopy measurements reveal that hydrogen atoms can go underneath the gr

Flow-injection assay of the pathogenic bacteria using lectin-based quartz crystal microbalance biosensor

A novel flow-injection assay of the pathogenic enterobacteria using novel lectin-based quartz crystal microbalance (QCM) biosensor has been proposed. The biosensing part of the analytical device contained the lectins - Concanavalin A, lectins from Ulex europeus, Maackia amurensis, Lens culinaris, wheat germ agglutinin - immobilized on the gold surface of quartz crystal electrode which served as a

Clinical effect of stereotyped B-cell receptor immunoglobulins in chronic lymphocytic leukaemia: a retrospective multicentre study

Background About 30% of cases of chronic lymphocytic leukaemia (CLL) carry quasi-identical B-cell receptor immunoglobulins and can be assigned to distinct stereotyped subsets. Although preliminary evidence suggests that B-cell receptor immunoglobulin stereotypy is relevant from a clinical viewpoint, this aspect has never been explored in a systematic manner or in a cohort of adequate size that wou

Rainfall and Flood Frequency Analysis in Pahang River Basin, Malaysia

In the past years different parts of the Pahang River basin have been affected by problems related to flooding. Many people died or were dislocated from their place, and government and private properties have been damaged causing huge impact on the country’s economy. The main reason for this catastrophe is the lack of appropriate knowledge about the river ba-sin’s hydrology. The rapid industrializ

The Chinese automotive industry: WTO accession, problems in going global and future potential

The Chinese economy has been growing with a pace and duration that the world has never seen before. Since 1978, the country has been facing a constant economic growth for more than 30 years. One of the pillars of the economy is the automotive industry; an interesting mixture of Joint Ventures and independent companies. The competition is cut throat and has even been more intense after the China’s

The Swedish ankle arthroplasty register - An analysis of 531 arthroplasties between 1993 and 2005

Background Whether or not ankles can be replaced with reasonable safety has been the subject of debate. We present the results of a nationwide series of total ankle arthroplasties. Patients and methods All Swedish hospitals that implant or have implanted modern three-component ankle prostheses reported demographic data and date of index and revision surgery to a central register. After the data ha

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The Lepidoptera fauna of the Danish island of Anholt is surveyed, and 1160 species are recorded. Anholt is situated in Kattegat 44 km from Denmark and 47 km from Sweden. The history and environment of the island are briefly discussed, with special focus on the flora, and earlier studies of the Lepidopterera fauna of Anholt are dealt with. The present study is in first hand based on material collec

The pioneer gut microbiota in human neonates vaginally born at term - a pilot study.

The pioneer microbiota of the neonate may affect future actions of the immune system. This study aimed to map the pioneer microbiota in healthy neonates vaginally born at term. A subgroup of neonates born large for gestational age (LGA) was compared with the neonates appropriate for gestational age (AGA). Fecal samples were collected, within 48 hours after birth, from 79 neonates. Quantitative pol

Changes in phenolic antioxidants during chuno production (traditional Andean freeze and sun-dried potato)

Total antioxidant capacity (TAC), total phenolic compounds (TPH), total flavonoids (TF) and the amounts of individual phenolic compounds were assessed in Bolivian potato cultivars (various Solanum species) before, during and after the traditional freezing and sun-drying of potatoes known as chunos. The TAC of chunos ranged from 0.4 to 2.7 mu mol Trolox equivalents/g dry matter using 2,2'-azino-bis

High-speed biomarker identification utilizing porous silicon nanovial arrays and MALDI-TOF mass spectrometry

Speed and accuracy are crucial prerequisites in the application of proteomic methods to clinical medicine. We describe a microfluidic-based nanovial array for rapid proteolytic processing linked to MALDI-TOF MS. This microscale format consumes only minute amounts of sample, and it is compatible with rapid bioanalytical protocols and high-sensitivity readouts. Arrays of vials (300 mu m in diameter

Mannan-binding lectin in women with a history of recurrent vulvovaginal candidiasis.

OBJECTIVES: To determine the serum concentration of mannan-binding lectin (MBL), a component of the innate immune system, in women with a history of recurrent vulvovaginal candidiasis (RVVC) and to correlate the result to candida-cultures, contraceptive use, if any, and to different antifungal therapies. STUDY DESIGN: Twenty-nine women with a history of RVVC were investigated. Cultures of vulvar a