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Introduction: To reach the intended target group is crucial if the health effects potentially following health promoting interventions for seniors shall be realized. The aim of this study was to improve reach of health promotion during implementation in a Swedish municipality context.Material & Methods: A mixed-methods approach was applied during four phases in which recruitment and interventi

To be able to survive in the long run the medical device industry of today needs effective development processes and ways to secure quality. These development processes and quality assurance processes must follow the different laws and regulations over the world depending on what market the organisations are established on. Organisations have been developing medical devices and systems over many y

Galectins are β-galactoside-binding lectins, which are present in both the intracellular and extracellular environments of cells. During the last two decades, galectins have gained increasing interest as drug targets in various diseases, such as chronic inflammation (fibrosis) and cancer, in which galectins have been shown to play important, and sometimes rate-limiting, roles. Galectins have e.g.

Objective: We describe real-world evidence (RWE) from the nationwide Swedish and Danish registries that provide important information on incidence and outcome in multiple myeloma (MM). Method: First line treatment data on more than 10.000 MM patients from Denmark and Sweden between 2005–2018 are presented. Key results from research conducted within the Swedish and Danish myeloma registries are sum

Early trauma and failures in attachment attunement can affect future relational patterns, health and well-being. The processing of trauma, especially complex trauma, through adequate interventions may help integrate traumatic experiences, enhance health and quality of life. Despite years of clinical practice with Identity oriented psychotrauma therapy (IoPT), there is a lack of scientific research

Background: The incidence of detected ductal carcinoma in situ (DCIS) continues to increase and now accounts for 14% of all breast cancer, and 20%–25% of screen-detected cases. Treatment trends of DCIS are important in order to inform the ongoing debate about possible overdiagnosis and overtreatment, but have not been investigated for over a decade in Australia and New Zealand. Against this backgr

From November 12th to 13th in 1872, an extreme coastal flood event occurred in the south Baltic Sea. An unusual combination of winds created a storm surge reaching up to 3.5 m above mean sea level, which is more than a meter higher than all other observations over the past 200 years. On the Danish, German, and Swedish coasts, about 300 people lost their lives. The consequences of the storm in Denm

Application of concurrent engineering (CE) to machinery has to consider the type of production (individual, serial), product complexity and level of design. Product development (PD) involves four characteristic levels of design that requires specific activities. The characteristic design levels require definitions of the activities for providing the necessary software and other support for all pha

The present work illustrates the potential of a new diagnostic technique that allows the measurement of the coronal magnetic field strength in solar active regions by utilizing a handful of bright Fe x and Fe xi lines commonly observed by the high-resolution Hinode/EUV Imaging Spectrometer (EIS). The importance of this new diagnostic technique is twofold: (1) the coronal magnetic field is probably

Aim: To explore reach and experiences of participants during implementation of health-promoting meetings of seniors in a Swedish municipality context. Subjects and methods: A mixed-methods approach was used, including older people who were recruited consecutively and invited to participate as they applied for health care and/or home help services in the municipality. Inclusion criterion was alloca

Limited studies have focused on developing prognostic models with trans-omics biomarkers for early-stage lung adenocarcinoma (LUAD). We performed integrative analysis of clinical information, DNA methylation, and gene expression data using 825 early-stage LUAD patients from 5 cohorts. Ranger algorithm was used to screen prognosis-associated biomarkers, which were confirmed with a validation phase.

The discrepancy between social and biological clock due to sleep and wake up time difference across weekdays and weekends is referred as social jetlag. The overall aim of this study is to test whether there is an association between both screen time and nighttime texting and social jetlag among 13- to 15-year-old adolescents in Sweden. This study included a cross-sectional survey in which data wer

The effectiveness of health promotion for community-dwelling older people is well documented; however, there is a general lack of health economic evaluations. The aim of the present study was to evaluate long-term cost-effectiveness over 4 years of two health promoting interventions: senior meetings and a preventive home visit, for community-dwelling older people in relation to no intervention. We

Topology optimization is a mathematical tool for finding optimal distributions of material phases within a design domain. It is commonly used in early design stages to generate conceptual structural layouts. Ultimately, designs generated by topology optimization consist of distinct material phases with enhanced performance. Most research on topology optimization methods focuses on linear elastic m

Linguistic relativity is a notion that has been met with both praise and scorn. We argue that there is correlation between theorists’ general conceptions of the nature of language, and their stance toward linguistic relativity. Starting with the proponents of the thesis, we distinguish between the relativists of the early days (Boas, Whorf) and modern neo-Whofians (Levinson, Slobin), showing that

Flood risk is a great global concern that is not only affecting developing countries, but threatens to undermine sustainable development also in the most affluent advanced liberal democracies. While political inertia is delaying much needed global change, efforts to reduce risk and adapt to a changing climate are growing on more local levels. However, floods tend not to be bounded by geopolitical,

This study investigates the internal cooling processes affected by the tip bleed holes in gas turbine blades. Double bleed holes are fixed at the center of the blade tip near the pressure side and suction side, respectively. Five different arrangements of the holes along the center line of the tip are studied. The purely double holes are set as the Baseline. The purpose of the present study is to

International collaboration is clearly a key priority in higher education andresearch (HER) policy and practice. The competition for students and excellentresearch and teaching staff is now a global one and this is reflected inthe increasing salience of phenomena such as the Shanghai and Times HigherEducation Rankings for monitoring the performance of HER institutions. Thischapter takes its point

Climate warming has substantially advanced the timing of spring leaf-out of woody species at middle and high latitudes, albeit with large differences. Insights in the spatial variation of this climate warming response may therefore help to constrain future trends in leaf-out and its impact on energy, water and carbon balances at global scales. In this study, we used in situ phenology observations