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‘Save file empty’: ALM institutions’ and game developers’ thoughts regarding digital games preservation This master’s thesis examines attitudes towards the preservation of digital games in Malmö, Sweden. Malmö is one of Europe’s largest gaming hubs and is home to many game studios. Digital games are one of Sweden’s largest cultural exports but very little has been done in order to preserve this h

Equinatoxin II (EqtII), a eukaryotic pore-forming toxin, lyses cell membranes through a mechanism involving the insertion of its N-terminal α-helix into the membrane. EqtII pore formation is dependent on sphingomyelin (SM), although cholesterol (Chol) and membrane microdomains have also been suggested to enhance its activity. We have investigated the mechanism of EqtII binding and insertion by usi

Objective To identify predictors of response to methotrexate (MTX) in early rheumatoid arthritis (RA). Methods In the SWEFOT trial, patients with RA with symptom duration <1 year started MTX monotherapy (20 mg/weekly) and 405/487 continued until the 3-4-month visit. The primary outcome measure was the DAS28-based European League against Rheumatism (EULAR) response criteria. Multivariate logistic r

Background: Irritable bowel syndrome (IBS) and gastrointestinal (GI) dysmotility disorders have a similar clinical picture, although dysmotility disorders require the attention of a specialist. Patients with primary Sjogren's syndrome (pSS) have also been described to suffer from IBS-like symptoms. No objective marker is available to distinguish between the patients. A visual analogue scale has be

BackgroundThis placebo-controlled study assessed the effects of the once-daily inhaled corticosteroid (ICS) fluticasone furoate (FF) and long-acting beta(2)-agonist (LABA) vilanterol (VI) on early and late asthmatic responses (EAR/LAR) and airway hyper-responsiveness (AHR). MethodsPatients (n=27) were randomized to FF (100g), VI (25g), FF/VI (100/25g), and placebo for 21days (four periods). Allerg

For construction in rock a thorough pre-investigation is important in order to avoid unforeseen conditions which may delay the work. It is crucial to remember the results from this investigation in the further work, and use the experience from the construction to update the geological prognosis and reduce the uncertainties. Different geophysical methods have proved valuable tools in such investiga

“As long as it does not hurt anybody” - The treatment of sexual behaviors of people with dementia in dementia care facilities The aim of this study was to examine how sexual behaviors in dementia accommodations are treated by medical staff. We were interested in seeing what attitude the staff had to sexual behaviors in dementia care facilities, how they talked about sexuality, and if some sexual

Berggrunden i sydvästra Sverige består av bergarter som deformerades och metamorfoserades under den Svekonorvegiska kontinent kollisionshändelsen. Den så kallade ”Sveconorwegian Frontal Deformation Zone” norr om Vättern och Protoginzonen söder därom anses utgöra den östligaste gränsen för Svekonorvegisk omarbetning. Söder om Vättern är Protoginzonen en 20-30 km bred N-S deformationszon. FortsättniThe bedrock in the southwest of Sweden was deformed and metamorphosed during the Sveconorwegian orogeny. The Sveconorwegian Frontal Deformation Zone north of the lake Vättern and the Protogine Zone south of the lake is regarded as the eastmost boundary of Sveconorwegian reworking. South of lake Vättern the Protogine Zone is 20-30 km wide made up of a system of discrete ductile (and locally brittle

In recent years, new contributors to the marine silica cycle have emerged, including pico-sized phytoplankton (<2–3 µm in size) such as Synechococcus and picoeukaryotes. Their contribution and relevance to silica cycling are still under investigation. Field studies reporting the biogenic silica (bSi) standing stock in the pico-sized fraction are limited to silica-poor oligotrophic environments, an

Algoritmiska rekommendationer har blivit allt mer förekommande i vardagen. Från filmer, musik och potentiella partners till söta katter och roliga danser – sociala medieplattformar utvecklar kraftfulla algoritmer för att förutsäga vad användarna kommer tycka om och behöva. Algoritmiska rekommendationer föreslår dock inte samma innehåll till alla användare, utan anpassar sina rekommendationer dynamAlgorithmic recommendations have become ubiquitous in everyday life. From films, music, and potential partners to cute cats and silly dances, social media platforms develop powerful algorithms to predict what users might like and need. However, algorithmic recommendations do not suggest the same content to all users but instead adapt their recommendations dynamically through endless feedback loops

In banana cultivation, a considerable amount of the production is wasted every year because of various constraints present in the post-harvest management chain. Converting green banana pulp and peels into flour could help to reduce losses and enable the food sector to keep the product for an entire year or more. In order to use green banana fruit and peel flour in the food industry as a raw ingred

Background Preeclampsia is considered a major cause of maternal and fetal morbidity and mortality. The aim of the present case-control study in Sweden was to assess the hypothesized association between low serum vitamin D concentrations in early pregnancy and the risk of developing preeclampsia since vitamin D may play a role in early placental development. Methods The study included 296 women dia

Ovarian cancer is a heterogeneous disease. Data regarding familial risks for specific proband, age at diagnosis and histology are limited. Such data can assist genetic counseling and help elucidate etiologic differences among various histologic types of ovarian malignancies. By using the Swedish Family-Cancer Database, we calculated relative risks (RRs) for detailed family histories using a two-wa

This consensus statement is the product of the Second International Think Tank on Athlete Mental Health, held on the initiative of the International Society of Sport Psychology. The purposes of the Think Tank were to engage international sport psychology societies and organisations in a discussion about athlete mental health as embedded in an Olympic/Paralympic cycle, and to develop practical reco

Background: In any study with voluntary participation, self-selection risks leading to invalid conclusions. If the determinants of selection are observed, it is however possible to restore the parameters of interest by reweighting the sample to match the population, but this approach has seldom been applied in epidemiological research. Methods: We reweighted the Malmö Diet and Cancer (MDC) study b

It is known for more than 100 years that the intestinal microbes are important for the host's health and the last decade this is being intensely studied with a focus on the mechanistic aspects. Among the fundamental functions of the intestinal microbiome are the priming of the immune system, the production of essential vitamins and the energy harvest from foods. By now, several dozens of diseases,

Thanks to Bruno Galantucci, “experimental semiotics” is usually nowadays taken to mean the study of “novel forms of communication which people develop when they cannot use pre-established communication systems”. In spite of Galantucci’s claim to have picked the label because it was free, it has actually been used in different ways at least twice before: by Colin Ware, who takes it to be involved w

Global warming is driving environmental change in the Arctic. However, our current understanding of this change varies strongly among different environmental disciplines and is limited by the number and distribution of field sampling locations. Here, we use a quantitative framework based on multivariate statistical modeling to present the current state of sampling across environmental disciplines