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Positive Surgical Margins in Radical Prostatectomy: Outlining the Problem and Its Long-Term Consequences

Context: This review focuses on positive surgical margins (PSM) in radical prostatectomy (RP). Objective: To address the etiology, incidence, and oncologic impact of PSM and discuss technical points to help surgeons minimize their positive margin rate. An evidence-based approach to assist clinicians in counseling patients with a PSM is provided. Evidence acquisition: A literature search in English

Test-Retest Reliability of Isokinetic Knee Strength Measurements in Children Aged 8 to 10 Years.

BACKGROUND: Isokinetic dynamometry is a useful tool to objectively assess muscle strength of children and adults in athletic and rehabilitative settings. This study examined test-retest reliability of isokinetic knee strength measurements in children aged 8 to 10 years and defined limits for the minimum difference (MD) in strength that indicates a clinically important change. HYPOTHESIS: Isokine

New aspects of HbA1c as a risk factor for cardiovascular diseases in type 2 diabetes: an observational study from the Swedish National Diabetes Register (NDR)

Eeg-Olofsson K, Cederholm J, Nilsson PM, Zethelius B, Svensson A-M, Gudbjornsdottir S, Eliasson B (Institute of Medicine, Sahlgrenska University Hospital, University of Gothenburg, Gothenburg; Department of Public Health and Caring Sciences/Family Medicine and Clinical Epidemiology, Uppsala University, Uppsala; Department of Clinical Sciences, Lund University, University Hospital, Malmo; Departmen

Parental support in a changing society

Popular Abstract in Swedish I Sverige betonas idag alltmer det hälsofrämjande arbetet riktat mot barn, ungdomar och deras föräldrar. Olika föräldrastödsaktiviteter erbjuds. Det behövs ökad kunskap om varför vissa aktiviteter fungerar bättre än andra. Det är även viktigt att känna till föräldrarnas motiv för att deltaga och upplevelser av stödaktiviteten. Syftet med denna avhandling var att belysa In today's Swedish society there is increasing emphasis on health-promotive work among children, adolescents, and their parents. Knowledge is needed about why certain activities work better than others. It is important to study the parents' motives and experiences of participating in parental supporting programmes. In child health care, mostly among the nurses, there is a contrast between what th

Mycophenolic Acid Exposure after Administration of Mycophenolate Mofetil in the Presence and Absence of Ciclosporin in Renal Transplant Recipients

Background and objective: The pharmacokinetics of mycophenolic acid (MPA) are complex, with large interindividual variability over time. There are also well documented interactions with ciclosporin, and assessment of MPA exposure is therefore necessary when reducing or stopping ciclosporin therapy. Here we report on the pharmacokinetic and pharmacodynamic behaviour of MPA in renal transplant patie

Massive MIMO for Next Generation Wireless Systems

Multi-user MIMO offers big advantages over conventional point-to-point MIMO: it works with cheap single-antenna terminals, a rich scattering environment is not required, and resource allocation is simplified because every active terminal utilizes all of the time-frequency bins. However, multi-user MIMO, as originally envisioned, with roughly equal numbers of service antennas and terminals and freq

Modeling the acid-base properties of bacterial surfaces: A combined spectroscopic and potentiometric study of the gram-positive bacterium Bacillus subtilis

In this study, macroscopic and spectroscopic data were combined to develop a surface complexation model that describes the acid-base properties of Bacillus subtilis. The bacteria were freeze-dried and then resuspended in 0.1 M NaCl ionic medium. Macroscopic measurements included potentiometric acid-base titrations and electrophoretic mobility measurements. In addition, ATR-FTIR spectra of wet past

NANC transmitters in the female pig urethra--localization and modulation of release via alpha 2-adrenoceptors and potassium channels

1. To investigate further the release, localization and identity of a non-nitrergic mediator of smooth muscle relaxation in the female pig urethra, we studied the effects of drugs acting at alpha 2-adrenoceptors or K+ channels, the effects of capsaicin and chemical sympathectomy, and the actions of several transmitter candidates. 2. Electrical field stimulation (EFS; frequencies above 12 Hz) of sp

Sydvästsvensk a-genitiv - en levande relikt

In modern standard Swedish genitive is marked by -s, which, according to the standard analyses, is a phrasal clitic, viz. [mannen på gatan]s åsikt (man on street-s opinion). In dialects in parts of Småland, Halland, and Västergötland a variant on -a or -e, here called a-genitive, is used, primarily on proper names, viz. Erik-a bil (Erik-gen car) ‘Erik’s car’, a form that should be compared to the

How to develop an administration tool to fit first-time user who lack expertise knowledge

The purpose of this bachelor thesis is to develop an administration tool that will be used by a helpdesk in IKEA IT. The helpdesk members have a lot of responsibilities and have to perform various tasks on a daily basis, thus the goal is to develop an administration tool that has an interface which allows a helpdesk member to perform basic tasks without needing any prior education or experience of

Nämndemän i den dömande verksamheten: en rättssociologisk undersökning om nämndemännen på Lunds tingsrätt följer de rättsliga normerna

After a recent discussion in the media about suitability and role lay judges in the courts, I thought their role and function should be investigated further as it is both an interesting and topical issue. The purpose of this study was to determine if lay judges follow the legal standards that govern their work and if there are trends that suggest that political views can influence the verdict, and

Exploratory testing with the help of a test tool

Exploratory testing (ET) is a test technique used to test software. It is a free way (compared to scripted test) of testing, where the tester takes notes during the test session. The tester has the option to select his own way when testing the software, he learns and tests at the same time. Notes are the result from the test session and are used to see what has been tested, e.g. the outcome and th

Utveckling av driven hjulplog till betupptagare

This report is a result of a Master Thesis project in mechanical engineering by Niklas Henriksson. It was done at Edenhall from September 2010 to May 2011. Edenhall has the past fifty years developed and manufactured bet harvesters. Vibrat-ing plows have long been the most common plow type as it can handle the most working condition. However this plow type has always been expensive in mainten-ance

Alumni as Lifelong Learners Towards a Business Model for Lifelong Learning in Higher Education

Lifelong Learning (LLL) involves the formal and informal education and learning of individuals and by extension society in a bid to function efficiently in today’s knowledge world. This Learning is not limited by age, race, or other susceptible circumstances; it is instead encouraged and seen in the contexts of adult learning, continuing learning, and work/ professional learning. By de-facto, it i

Sustainability Reporting

In the modern business environment, there is growing number of companies placing weight on sustainability-related issues, such as waste management, local communities, use of resources etc. At the same time such stakeholders as investors, consumers, employees and communities are increasingly interested in understanding company’s efforts and progresses in the area of sustainability. With that respec

"Man känner sig behövd liksom" En undersökning om kuratorer inom gymnasiesärskolan

Author: Ebba Hedström Title: ”You feel useful” – A studie about counsellers work in the school for children with intellectual disabilities [translated title] This study concerns the councellors work with children in special programs for pupils with intellectual disabilities. The purpose was to se how counceller work with the children in special programs for pupils with intellectual disibilities.

Management of cerebrospinal fluid leak during endoscopic pituitary surgery

Objective: Dural opening and closures are major steps in endoscopic pituitary surgery. Restoring the normal anatomy at the end of the procedure creates a natural barrier between the intrasellar compartment and the sinonasal cavity. Methods: In this study, we present a relatively simple dural opening and closure technique for endoscopic pituitary surgery. This technique provides a better alternativ

Development and Validation of a Risk Prediction Model for Esophageal Squamous Cell Carcinoma Using Cohort Studies

INTRODUCTION: Esophageal squamous cell carcinoma (ESCC) carries a poor prognosis, but earlier tumor detection would improve survival. We aimed to develop and externally validate a risk prediction model based on exposure to readily available risk factors to identify high-risk individuals of ESCC.METHODS: Competing risk regression modeling was used to develop a risk prediction model. Individuals' ab

"Skilda världar" : skolbibliotekariers undervisning i informationssökning i gymnasieskolan

?SEPARATE WORLDS?. School librarians teaching in information seeking in high school. The aim of this Master's thesis is to study how information seeking is taught in high school and how school librarians describe their experiences of teaching information seeking. Five school librarians from five different high schools (gymnasium) in Skåne participated in the study. The empirical data derives