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AIMS: Previous studies have identified sex disparities in the use of cardiac resynchronization therapy (CRT) and implantable cardioverter defibrillators (ICD), although the basis of underutilization in women remains poorly understood. The aim of this study was to assess sex differences in patterns of CRT use with our without ICD.METHODS AND RESULTS: In this cross-sectional study using the National
Mirtazapine pharmacokinctic (PK) data from patients on long-term treatment for major depression have never been investigated. For this reason, in a large naturalistic outpatient study (prospective, multicenter, open-labeled, and noncomparative) conducted in Sweden in the period 2000 2002, one of the main objectives was to outline the inter- as well as intraindividual PK variance of mirtazapine and
Popular Abstract in Swedish Sammanfattning I debatter och forskning om narkotikapolitik anges den svenska och nederländska modellen ofta som ett motsatspar. Såväl målet för, som utformningen av, narkotikapolitiken har framställts som radikalt olika. Detta synsätt kan sägas vara riktigt. Målet för den svenska narkotikapolitiken är att skapa ett narkotikafritt samhälle. Den nederländska strävar efteIn debates about the Swedish and Dutch drug policies are usually positioned as opposites. The goal for the Swedish drug policy is to create a 'drug-free society'; while in the Netherlands a harm reduction approach prevails. In this study a drug policy is considered a practice of formal social control that can develop differently depending on the contexts in which it emerged. The period studied sta
Background: ACMG/AMP and AMP/ASCO/CAP have released guidelines for variation interpretation, and ESHG for diagnostic sequencing. These guidelines contain recommendations including the use of computational prediction methods. The guidelines per se and the way they are implemented cause some problems. Methods: Logical reasoning based on domain knowledge. Results: According to the guidelines, several
Serum levels of Anti-Mullerian Hormone (AMH) have been shown to be biomarker for prediction of the quantitative aspects of ovarian reserve. On the male side, sperm chromatin structure assay (SCSA) DNA fragmentation index (DFI) has been demonstrated to be an important predictor of outcomes in standard IVF procedures but to less degree in intracytoplasmic sperm injection procedures (ICSI). The purpo
Background: Traumatic brain injuries continue to be a significant cause of mortality and morbidity worldwide. Most traumatic brain injuries are classified as mild, with a low but not negligible risk of intracranial hemorrhage. To help physicians decide which patients might benefit from a computerized tomography (CT) of the head to rule out intracranial hemorrhage, several clinical decision rules h
Background: As healthcare becomes increasingly complex, new methods are needed to identify weaknesses in the system that could lead to increased risk. Traditionally, the focus for patient safety is to study incident reports and adverse events, but that starting point has been contested with a new era of safety investigations: the analysis of everyday clinical work, and the resilient healthcare. Th
Radon (222Rn) gas is the largest source of public exposure to naturally occurring radioactivity and the identification of radon priority areas is required by the Council Directive 2013/59/Euratom. Radon is also used as a tracer to improve atmospheric transport models and to indirectly estimate greenhouse gas (GHG) fluxes using the Radon Tracer Method (RTM). This method is based on the correlation
IntroductionFloods are the most common type of natural disaster worldwide and are projected to become morefrequent and more extreme. Cambodia is prone to annual, seasonal flooding. Floods impact health inmany ways and can disrupt the health system through destruction of infrastructure and loss ordiversion of human, economic and physical resources. Through knowledge acquisition and skillsdevelopmen
OBJECTIVE: The presence of tachycardia in critically ill patients is frequently used as an indication of severity of illness and to guide treatment decisions but can be influenced by body temperature, thus confounding its interpretation. There are few data available on the relationship between body temperature and heart rate in critically ill patients. DESIGN: Retrospective analysis of prospective
Background: To describe life-space mobility and explore associations of motor and non-motor symptoms with life-space mobility in people with Parkinson’s disease (PD).Methods: About 164 community-dwelling persons with PD (mean age 71.6 years, 64.6% men) received a postal survey and a subsequent home visit. Motor assessments included perceived walking difficulties (Walk-12G), mobility (Timed Up and
This thesis focuses on the languages of thought of multilingual students writing in English, a non-native language. The study examines which languages are used as languages of thought and what functions these languages serve for year-9 students (age 15-16) in a Swedish high school while writing an essay in English under exam-like conditions. The study sheds detailed light on individual differences
Over the past few years, environmental sustainability as a whole has gained significantly more attention globally, and the connection between sustainability and the built environment has been made clear. The built environment is now more widely known to have major implications on both climate change, and resource use. This study draws on a previous study, which identified environmental pressure as
Accurate measurement and prediction of laminar burning velocity is important for characterization of premixed combustion properties of a fuel, development and validation of new kinetic models, and calibration of turbulent combustion models. Understanding the variation of laminar burning velocity with thermodynamic conditions is important from the perspective of practical applications in industrial
Invasive alien species threaten biodiversity with domestic gardens acting as a major pathway for the introduction of alien species. Even though the Nordic region is not currently a hotspot for biological invasions, the number of invasions in the Nordic area has been predicted to increase due to climate change. Given a time lag between introduction and invasion, many non-invasive horticultural alie
The report is based on the use of alternative materials in road construction. The alternative materials included are crushed concrete, crushed asphalt and air cooled blast furnace slag. Differences and similarities exist between the use of alternative materials in Sweden and Denmark. Denmark has no use of air cooled blast furnace slag, but they have a greater use of crushed concrete and crushed as
I uppsatsen utreds indirekta förebilders påverkan på svenska förtonåringars modeval av kläder och skor. Mycket av den forskning som gjorts tidigare berör andra marknader än den svenska och andra produkter än kläder varför vi anser vårt valda område tämligen outforskat. Vi redogör i uppsatsen för teorier som behandlar modespridning, barnens roll som konsumenter, kommunikation, varumärken, referensg
Study purpose: The maritime shipping industry, particularly the commercial sector, is a significant contributor to carbon emissions and environmental pollution. Various solutions are being proposed to enhance the sector's sustainability, including the adoption of wind propulsion technologies. However, the economic feasibility of these technologies on a large scale remains uncertain. Despite th
The success of a company increasingly depends on the efficiency and effectiveness on its activities along the product life cycle. In the effort of optimizing its activities, companies must integrate themselves. Due to the significance packaging has within many of these activities, it is of utmost importance to integrate product and packaging development activities in order to optimize processes.
Every day, new decisions are made, ranging from trivial to critical, and their impact can vary greatly. Despite these differences, all decisions share a common goal: to choose the best possible action based on the knowledge available at the time. In some cases, past events offer little insight into what lies ahead. However, in many situations, especially in structured environments, historical patt
