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Diagnostic and prognostic implications of a three-antibody molecular subtyping algorithm for non-muscle invasive bladder cancer

Intrinsic molecular subtypes may explain marked variation between bladder cancer patients in prognosis and response to therapy. Complex testing algorithms and little attention to more prevalent, early-stage (non-muscle invasive) bladder cancers (NMIBCs) have hindered implementation of subtyping in clinical practice. Here, using a three-antibody immunohistochemistry (IHC) algorithm, we identify the

Increasing sex differences in the use of cardiac resynchronization therapy with or without implantable cardioverter-defibrillator

AIMS: Previous studies have identified sex disparities in the use of cardiac resynchronization therapy (CRT) and implantable cardioverter defibrillators (ICD), although the basis of underutilization in women remains poorly understood. The aim of this study was to assess sex differences in patterns of CRT use with our without ICD.METHODS AND RESULTS: In this cross-sectional study using the National

Protocol for the systematic review of return-to-activity criteria in adolescent patients following an anterior cruciate ligament reconstruction

Background: Anterior cruciate ligament (ACL) rupture is a debilitating knee injury associated with sequela such as joint instability and progressive degeneration. Unfortunately, following surgical ACL reconstruction in adolescents, the rates of ACL graft failure range from 17 to 19%. A contributing factor to the high reinjury rate in this population may be the limited evidence regarding appropriat

Problems in variation interpretation guidelines and in their implementation in computational tools

Background: ACMG/AMP and AMP/ASCO/CAP have released guidelines for variation interpretation, and ESHG for diagnostic sequencing. These guidelines contain recommendations including the use of computational prediction methods. The guidelines per se and the way they are implemented cause some problems. Methods: Logical reasoning based on domain knowledge. Results: According to the guidelines, several

Multilingual Students' Writing in English : The Role of Their L1(s)

This thesis focuses on the languages of thought of multilingual students writing in English, a non-native language. The study examines which languages are used as languages of thought and what functions these languages serve for year-9 students (age 15-16) in a Swedish high school while writing an essay in English under exam-like conditions. The study sheds detailed light on individual differences

Familial risks of second primary cancers and mortality in ovarian cancer patients

Background: With improving survival in ovarian cancer, second primary cancers (SPCs) and their etiological foundations are becoming an issue. The ways in which family history may influence the occurrence of SPCs and the related mortality are not well known. Methods: Based on the Swedish Family-Cancer Database, we identified 11,300 ovarian cancer patients and followed them for diagnoses of SPCs unt

A comprehensive review of measurements and data analysis of laminar burning velocities for various fuel+air mixtures

Accurate measurement and prediction of laminar burning velocity is important for characterization of premixed combustion properties of a fuel, development and validation of new kinetic models, and calibration of turbulent combustion models. Understanding the variation of laminar burning velocity with thermodynamic conditions is important from the perspective of practical applications in industrial

Life-Space Mobility in Parkinson’s Disease: Associations with Motor and Non-Motor Symptoms

Background: To describe life-space mobility and explore associations of motor and non-motor symptoms with life-space mobility in people with Parkinson’s disease (PD).Methods: About 164 community-dwelling persons with PD (mean age 71.6 years, 64.6% men) received a postal survey and a subsequent home visit. Motor assessments included perceived walking difficulties (Walk-12G), mobility (Timed Up and

Context-based Adaptation of Change Management Practices - A Systematic Literature Review and a Research Agenda

Despite the breadth of change management research, limited attention has been paid to how change management practices are adapted to specific organizational contexts. This review addresses this gap by examining how context is conceptualized in relation to change management. Based on a contingency approach, which underscores that processes and structures of an organization need to be adapted to the

solfläckar – Vetenskap och Hälsa

solfläckar – Vetenskap och Hälsa Vetenskap och hälsa Populärvetenskapligt om medicinsk forskning i Skåne Teman Podd Tidskrift Prenumerera Om webbplatsen Kontakt Sök Sök Etikett: solfläckar Solen som stjärna 2011-06-07 Det höga vattenfallet gör ont när det drabbar dig med all kraft. Så fungerar också solens UV-strålning när den är som kraftigast. – Det är en energirik, kortvågig strålning som utlös

https://www.vetenskaphalsa.se/tag/solflackar/ - 2026-05-08

Innovationsbroschyr se low 1

LUNDS UNIVERSITET FORSKNING OCH INNOVATION Ny mEDICIN mOT bLODCANCER 5u mED STADEN SOm mILjöFöREbILD 6u LUNDENSISKA INNOVATIONER OCH UPPTÄCKTER 8 - 9u STORA FöRVÄNTNINGAR På KRAFTFULLT mIKROSKOP 10u 2 EN bREDARE SyN På INNOVATION LUNDS UNIVERSITET ÄR, med sina åtta fakulteter, en enorm kunskapsbank. Ett universitet präglat av mångfald är ett universitet med goda möjlighe- ter till innovation och n

https://www.lu.se/sites/www.lu.se/files/innovationsbroschyr_se_low_1.pdf - 2026-05-08

Sairla research brief 2 agricultural transformation in tanzania

Microsoft Word - SAIRLA research brief 2_Agricultural transformation in Tanzania.docx What drives agricultural transformation in Tanzania? Lessons from a political economy analysis SAIRLA Research Brief 2 Anna Mdee, Overseas Development Institute/ University of Leeds and Alesia Ofori Dedaa, Overseas Development Institute June 2018 In this briefing we explore the politics and institutions of agricu

https://www.keg.lu.se/en/sites/keg.lu.se.en/files/sairla_research_brief_2_agricultural_transformation_in_tanzania.pdf - 2026-05-08

Hantering Av Spill Och Läckage Av Kemiska Och Biologiska smittförande Riskkällor

Hantering av spill och läckage av ke-miska och biologiska/smittförande riskkällor Sida 1 av 13 Diarienummer: V 2025/44 Handlingstyp: 2.3.2 Rutin Gäller för: Lunds universitet Datum: 2025-01-13 Version: 1.0 Framtaget av: Miljöfunktionen, LU Byggnad Godkänd av: Miljöchef Hantering av spill och läckage av ke- miska och biologiska/smittförande risk- källor 1 Syfte Syftet med denna rutin är att säkerst

https://www.hr-webben.lu.se/sites/hr-webben.lu.se/files/2026-01/Hantering%20av%20spill%20och%20l%C3%A4ckage%20av%20kemiska%20och%20biologiska_smittf%C3%B6rande%20riskk%C3%A4llor.pdf - 2026-05-08

A Case Study of Training for Flood Management in Cambodia: : Perspectives from Healthcare Professionals and Key Training Stakeholders

IntroductionFloods are the most common type of natural disaster worldwide and are projected to become morefrequent and more extreme. Cambodia is prone to annual, seasonal flooding. Floods impact health inmany ways and can disrupt the health system through destruction of infrastructure and loss ordiversion of human, economic and physical resources. Through knowledge acquisition and skillsdevelopmen

The Relationship between Heart Rate and Body Temperature in Critically Ill Patients

OBJECTIVE: The presence of tachycardia in critically ill patients is frequently used as an indication of severity of illness and to guide treatment decisions but can be influenced by body temperature, thus confounding its interpretation. There are few data available on the relationship between body temperature and heart rate in critically ill patients. DESIGN: Retrospective analysis of prospective

Patients’ experience of a novel interdisciplinary nurse-led self-management intervention (INSELMA)—a qualitative evaluation

Background: Despite continuous improvements in anti-rheumatic pharmacological treatment, people with chronic inflammatory arthritis still report substantial disease impact. Based on the framework for complex interventions, we thus developed INSELMA, a novel nurse-coordinated multidisciplinary self-management intervention for patients with rheumatoid arthritis, psoriatic arthritis or axial spondylo

The Environmental Gaze : Visual perspectives on monitoring landscapes of ecological devastation

The increasing application of monitoring technologies and the specific perspectives afforded through them are transforming our understanding of and relationship to our environment. Through systems of mass data accrual, the physical processes and elemental attributes of regional and planetary landscapes are transformed into media, such as digital multilayered maps, graphs, thermal imaging, models,

Left Ventricular Diastolic Function in Children with Atrial Septal Defects Improves After Closure by Means of Increased Hydraulic Force.

Hydraulic force aids diastolic filling of the left ventricle (LV) by facilitating basal movement of the atrioventricular plane. The short-axis atrioventricular area difference (AVAD) determines direction and magnitude of this force. Patients with atrial septal defect (ASD) have reduced LV filling due to the left-to-right shunt across the atrial septum and thus potentially altered hydraulic force.

Knowledge as a Public Good: Reconceiving the Purpose and Methods of Knowledge Production

This volume originally started as a conversation between academics from across the Arab world, all of whom have bridged their academic careers or professional development expertise to the public sphere in order to use their knowledge more actively to push for progressive, democratic change in their respective countries. Over the course of the conversation, Arab engaged scholars and activists share

Radon metrology for use in climate change observation and radiation protection at the environmental level

Radon (222Rn) gas is the largest source of public exposure to naturally occurring radioactivity and the identification of radon priority areas is required by the Council Directive 2013/59/Euratom. Radon is also used as a tracer to improve atmospheric transport models and to indirectly estimate greenhouse gas (GHG) fluxes using the Radon Tracer Method (RTM). This method is based on the correlation