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BACKGROUND: Tofacitinib is a Janus kinase inhibitor for the treatment of ulcerative colitis (UC). Prospective real-world data are scarce.OBJECTIVES: To collect data on clinical outcomes, including health-related quality of life (HRQoL) and fatigue during treatment with tofacitinib.DESIGN: This is a prospective observational multicentre study in Sweden. In this analysis, outcomes at weeks 2, 8 and

The development of EU labour and social law has been described as a pendulum in the sense of focus shifting between economic interests, such as competitiveness for industry, and social interests, such as improving working and living conditions. This view is to a large extent based on the presumption that those interests are contrasting and pursuing one of them would necessarily exclude the promoti

This research monograph explores new frontiers in Markov chains. Although time-homogeneous Markov chains are well understood, this is not at all the case with time-inhomogeneous ones. The book, after a review on the classical theory of homogeneous chains, including the electrical network approach, introduces several new models which involve inhomogeneous chains as well as related new types of rand

This thesis investigates the role of trust in the context of decentralised finance (DeFi). Representing a new paradigm shift in finance, DeFi emerge from the technological developments that we have witnessing in the last decades, particularly decentralised ledger technologies (DLTs) of which Blockchain is perhaps the most popular. DeFi is changing the way that firms raise financial capital and a c

The purpose of this thesis’ topic is to investigate the evolutionary dispersal of the Charon’s fee or Obolus rite outside the Roman provinces in Northern Europe, with a specific focus on Roman Iron Age and Migration Period Scandinavia. The aim of this study is therefore to add further understanding to the spread of Roman cultural influences outside the imperial borders and what made Roman material

The aim of this paper is to study the extent to which non-Annex I countries are implementing or exploring select actions that support both climate change mitigation and sustainable development objectives in the energy sector. The research is based on a survey of the national communications of 100 non-Annex I Parties to the UNFCCC. Although national communications are intended to provide informatio

This paper ad to the body of knowledge on the implementation ofthe e-Government and aims to describe how this process was carried out inthe Delta municipality in Northern Italy. This organization is a public organization in an economically important Region and provides services to entrepreneurs such as validation for opening a new business. An interpretativeapproach used with several interviewees

The aim of this paper is to study the extent to which non-Annex I countries are implementing or exploring select actions that support both climate change mitigation and sustainable development objectives in the energy sector. The research is based on a survey of the national communications of 100 non-Annex I Parties to the UNFCCC. Although national communications are intended to provide informatio

Stora förändringar och varierad elproduktion har lett till många osäkerheter i elsystemets marknader. Balanseringsverktygen har därmed hamnat i rampljuset med stor inkomstpotential idag och möjligen även långt framöver. Denna rapport visar att det finns stora möjligheter för vätgassystem och batterier att medverka på dessa marknader. En förväntad fördubbling av elproduktion under de kommande 20 årIn order to move away from fossil fuels many governments and industries are focusing their new investments in electricity and alternative fuels such as green hydrogen from electrolyzers using renewable electricity. High investment costs and electricity costs are a hindrance for the future development of a hydrogen economy which can utilize an increasing intermittent power generation. The aim of th

Purpose: This study’s purpose is to study the long term effects of M&A and to examine whether stock price is the only determinant of post-merger performance or if operating performance can be used as an additional determinant. How underlying variables impact these measures are also part of this study´s purpose. Methodology: A quantitative approach is used where two event studies are conducte

Purpose: This research aims to gain an understanding on how consultants in small consultancies, who also hold internal human resource responsibilities, promote their organisation in employee and employer branding. Relevance: Due to the ambiguous consultancy profession and the high potential for individual influences on the corporate brand, branding becomes a very germane topic in our particular r

Climate change poses a significant threat to global stability, with rising temperatures leading to severe environmental and economic impacts. In response, innovative policy mechanisms such as the Global Carbon Reward (GCR) have been designed to enhance the effectiveness of carbon pricing strategies. The foundational aspect of the GCR is a carbon reward, which acts as a financial incentive distribu

I den pågående kampen mot klimathotet har Europeiska unionen antagit en ledande roll för att fullfölja skiftet mot en grön ekonomi, bland annat genom att fokusera på att stärka konkurrenskraften avseende tillverkningen av netto-noll energiindustrin och säkra de nödvändiga råvarorna för denna omställning. För att möjliggöra detta presenterade den Europeiska kommissionen i mars 2023, i samband med pIn the global race against climate change, the answer of the European Union is the transition towards a green economy by focusing on strengthening the competitiveness of the net-zero technology industry and securing the necessary critical materials. To do so, the Union presented two legislative acts in the European Green Deal Industrial Plan in 2023, amongst which the Net-Zero Industry Act. While

While foreign direct investments (FDI) are promoted as a vehicle for economic development their environmental consequences are less established. This study tests the hypotheses that 1) FDI led to environmental degradation in form of increased greenhouse gas emissions during Sub-Saharan Africa´s recent growth spurt but that 2) this impact was felt to a lesser extent in countries with a higher quali

Factor H is an inhibitor of the complement system, essential for controlling the alternative pathway and also playing a crucial role in various cellular functions. In this thesis, we identified new intriguing functions of FH as a survival factor for primary human monocytes, promoting their differentiation into immunosuppressive macrophages. We showed that FH is expressed by human breast cancer cel

This article focuses on how academic and industrial leaders view central aspects of the initiation, collaboration process, and the outcomes in government-funded R&D projects. In much previous work on university-industry collaborations (UICs), universities or researchers and/or firms have been studied without any direct reference to the other party, thus neglecting the fact that the motivations