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Successful treatment of experimental glomerulonephritis with IdeS and EndoS, IgG-degrading streptococcal enzymes

Background. Anti-glomerular basement membrane (anti-GBM) disease often results in end-stage renal failure despite therapy with plasma exchange and immunosuppressive drugs. The newly discovered streptococcal enzymes IgG-degrading enzyme of S.pyogenes (IdeS) and endoglycosidase S (EndoS) act with remarkable specificity on circulating IgG. In this study, we investigate their ability in vivo to preven

Towards alkali-stable polymers and hydroxide exchange membranes functionalized with alicyclic quaternary ammonium cations

In the current work, cationic polymers functionalized with N-alicyclic quaternary ammonium (QA) cations were synthesized and characterized as potential hydroxide exchange membranes (HEMs) for application in fuel cells. Three different polymers, namely poly(arylene ether sulfone), spiro-ionene and poly(arylene alkylene), were explored as polymer backbones for the HEMs. Various mono- and spirocyclic

IgG Binds Escherichia coli Serine Protease EspP and Protects Mice From E. coli O157:H7 Infection

Shiga toxin-producing Escherichia coli O157:H7 is a virulent strain causing severe gastrointestinal infection, hemolytic uremic syndrome and death. To date there are no specific therapies to reduce progression of disease. Here we investigated the effect of pooled immunoglobulins (IgG) on the course of disease in a mouse model of intragastric E. coli O157:H7 inoculation. Intraperitoneal administrat

Development and validation of a machine learning-based model to predict isolated post-challenge hyperglycemia in middle-aged and elder adults : Analysis from a multicentric study

Introduction: Due to the high cost and complexity, the oral glucose tolerance test is not adopted as the screening method for identifying diabetes patients, which leads to the misdiagnosis of patients with isolated post-challenge hyperglycemia (IPH), that is., patients with normal fasting plasma glucose (<7.0 mmoL/L) and abnormal 2-h postprandial blood glucose (≥11.1 mmoL/L). We aimed to develop a

Group A streptococci induce stronger M protein-fibronectin interaction when specific human antibodies are bound

Group A streptococcus (GAS) is a highly adapted, human-specific pathogen that is known to manipulate the immune system through various mechanisms. GAS’ M protein constitutes a primary target of the immune system due to its spatial configuration and dominance on the bacterial surface. Antibody responses targeting the M protein have been shown to favor the conserved C region. Such antibodies (Abs) c

Mode of Coreceptor Use by R5 HIV Type 1 Correlates with Disease Stage: A Study of Paired Plasma and Cerebrospinal Fluid Isolates.

Abstract Through the use of chimeric CXCR4/CCR5 receptors we have previously shown that CCR5-tropic (R5) HIV-1 isolates acquire a more flexible receptor use over time, and that this links to a reduced viral susceptibility to inhibition by the CCR5 ligand RANTES. These findings may have relevance with regards to the efficacy of antiretroviral compounds that target CCR5/virus interactions. Compartme

Practical Aspects of Reduced Complexity LDPC Decoding using Forced Convergence

This thesis is an extension to the previous work done at Department of EIT in investigating the complexity reduction of LDPC decoding using the stochastic approximation method to improve the energy efficiency of energy-limited applica- tions, such as in mobile phones. The research carried out in this thesis investigates the complexity and conver- gence results of adaptive performance control algorit

Resting-State Electroencephalogram Complexity Is Associated With Oral Ketamine Treatment Response : A Bayesian Analysis of Lempel–Ziv Complexity and Multiscale Entropy

Introduction: Subanesthetic doses of ketamine are a promising novel treatment for suicidality; however, the evidence for predictive biomarkers is sparse. Recently, measures of complexity, including Lempel–Ziv complexity (LZC) and multiscale entropy (MSE), have been implicated in ketamine's therapeutic action. We evaluated electroencephalogram (EEG)-derived LZC and MSE differences between responder

Antigenic peptide delivery to antigen-presenting cells using a CD40-coiled coil affinity-based platform

Delivery of antigenic peptides to antigen presenting cells (APCs) such as dendritic cells (DCs) using monoclonal antibodies (mAbs) is an attractive approach to evoke antigen-specific T cell activation and improve drug efficacy. Peptide linkage to mAbs has previously been achieved through genetic fusion, chemical conjugation, nano-engineered platforms and high affinity peptides. In this study, we h

LU Holding Årsredovisning 2020

LU Holding AB 556500-1467 Box 117, SE - 221 00 Lund, Sweden, Visiting address The Spark, Medicon village, Scheeletorget 1, Lund Telephone +46 46-222 00 00 Internet www.innovation.lu.se 1 AÅ rsredovisning för LU Holding AB 556500-1467 Räkenskapsåret 2020-01-01 – 2020-12-31 Transaktion 09222115557446406774 Signerat BA, JA, SF, BN, HP, CW, CE, UR, ST, LW, ME LU Holding AB 556500-1467 Box 117, SE -

https://www.innovation.lu.se/sites/innovation.lu.se/files/2021-08/LU%20Holding%20a%CC%8Arsredovisning%202020.pdf - 2026-05-14

Courts and Democracy in a One-Party State: Judicial Independence in China - The Raoul Wallenberg Ins

Courts and Democracy in a One-Party State: Judicial Independence in China - The Raoul Wallenberg Institute of Human Rights and Humanitarian Law Skip to content Search for: Search Button Home About Us Who We Are Our History About Raoul Wallenberg Our Theory of Change Staff Opportunities Annual Reports Whistleblower Our work What we do Multi-Disciplinary Research Higher Education Strategic Advice an

https://rwi.lu.se/publications/courts-and-democracy-in-a-one-party-state-judicial-independence-in-china/ - 2026-05-15

MEDI-563, a humanized anti-IL-5 receptor alpha mAb with enhanced antibody-dependent cell-mediated cytotoxicity function

Background: Peripheral blood eosinophilia and lung mucosal eosinophil infiltration are hallmarks of bronchial asthma. IL-5 is a critical cytokine for eosinophil maturation, survival, and mobilization. Attempts to target eosinophils for the treatment of asthma by means of IL-5 neutralization have only resulted in partial removal of airway eosinophils, and this warrants the development of more effec

Utvärderingsrappot, Aktiv Fritid

Barns rätt till lek, vila och fritid - en utvärdering av ett ESF-projekt Anna Lundberg, Hedvig Obenius och Anna Sonander Research Report in Sociology of Law 2026:1 Research Report in Sociology of Law 2026:1 SOCIOLOGY OF LAW • LUND UNIVERSITY ISSN 1404-1030 P.O. BOX 42 • SE-221 00 LUND • SWEDEN ISBN 978-91-7267-512-4 Barns rätt till lek, vila och fritid Barns rätt till lek, vila och fritid är en ut

https://www.soclaw.lu.se/sites/soclaw.lu.se/files/2026-03/Utv%C3%A4rderingsrappot,%20Aktiv%20Fritid.pdf - 2026-05-14

Fab fragments imprinted SPR biosensor for real-time human immunoglobulin G detection

F(ab) fragments imprinted surface plasmon resonance (SPR) chip was prepared for the real-time detection of human immunoglobulin G (IgG). In order to attach polymerization precursor on SPR chip, the SPR chip surface was modified with allyl mercaptan. F(ab) fragments of the IgG molecules were prepared by papain digestion procedure and collected by fast protein liquid chromatography (FPLC) system usi

1997cv cesilia sterner

contact@ceciliasterner.com www.ceciliasterner.com +46-707-516207 2001 Publikation #14, Rollon, Malmö 2000 Gallery C. Hjärne, Helsingborg 2000 Shoot- Moving Pictures by Artists, biograf Spegeln, Malmö 2000 Aura, Krognoshuset i Lund 1999 Rollon, www.rollon.net 1999 South City Drawings, The Pineapple 1999 Rollon, Panora, Malmö 1999 Whiteout Greyout Blackout, Barbacka konsthall, Kristianstad 1997 Mike

https://www.khm.lu.se/sites/khm.lu.se/files/1997cv_cesilia_sterner.pdf - 2026-05-15

Handelstad web version small

untitled Handelsstad i förvandling DEVRIM UMUT ASLAN & CECILIA FREDRIKSSON (RED) INST FÖR SERVICE MANAGEMENT OCH TJÄNSTEVETENSKAP | LUNDS UNIVERSITET 1 Handelsstad i förvandling 2 3 Handelsstad i förvandling 4 Redaktörer: Devrim Umut Aslan, Cecilia Fredriksson Omslagsillustration © Cecilia Fredriksson Foto © Devrim Umut Aslan © Författarna 2017 Lunds universitet Samhällsvetenskapliga fakulteten In

https://www.ses.lu.se/sites/ses.lu.se/files/handelstad_web_version_small.pdf - 2026-05-14

Miljöns betydelse för patienter som genomgår en elektiv röntgenundersökning

Miljön på röntgenavdelningar uppfattas ofta som sterila och opersonliga. Detta kan innebära obehag och främlingskänsla för patienter som genomgår längre undersökningar. Syftet med studien är att undersöka hur patienter upplever den fysiska miljön i röntgenrummet och om dekorationer, uppsatta i patienternas blickfång, innebär någon förändring av deras upplevelse. En kontrollgrupp patienter (n=39) f