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Studies on hereditary C2 deficiency: Frequent occurrence of severe infections, atherosclerosis and rheumatological manifestations

Popular Abstract in Swedish Komplementsystemet utgör en del av den medfödda immuniteten och är viktigt i försvaret mot angripande mikroorganismer. Ärftlig C2-brist (C2D) är en av de vanligaste bristerna inom komplementsystemet och förekommer i en frekvens av 1: 20 000 hos personer med västerländsk härstamning. I de aktuella undersökningarna har mer än 40 personer med C2D identifierats och observerThe complement system is a part of the innate immunity and is essential in the defence against microorganisms. Hereditary C2 deficiency (C2D) is one of the most common complement deficiency states with an estimated prevalence of 1:20,000 in persons of Western descent. In the present investigation, the identification of more than 40 C2D persons at a single centre combined with long observation peri

Utvc21 ht 2017 schedule 2017-09-29

BIDS UTVC21 Lectures and seminars 2017 (Updated 2017-09-29) Date Time Room Theme Activity Group Lecturer 30/8 10-12 Världen Meet Your Programme Coordinator Lec 1/1 AF 30/8 13-15 Världen Course Introduction Lec 1/1 TAX 1/9 10-12 Världen Introduction: questioning development Potter Ch. 1; Allen et al Ch. 1-2 Lec 1/1 YM 1/9 13-15 Världen Introduction: history and development Allen Ch. 1; Allen et al

https://www.keg.lu.se/sites/keg.lu.se/files/utvc21_ht_2017_schedule_2017-09-29.pdf - 2026-05-20

Analysis of HLA DR, HLA DQ, C4A, FcgammaRIIa, FcgammaRIIIa, MBL, and IL-1Ra allelic variants in Caucasian systemic lupus erythematosus patients suggests an effect of the combined FcgammaRIIa R/R and IL-1Ra 2/2 genotypes on disease susceptibility.

Dysfunction in various parts of immune defence, such as immune response, immune complex clearance, and inflammation, has an impact on pathogenesis in systemic lupus erythematosus (SLE). We hypothesised that combinations of common variants of genes involved in these immune functions are associated with susceptibility to SLE. The following variants were analysed: HLA DR3, HLA DQ2, C4AQ0, Fcgamma rec

The role of multiple injections on combustion in a light-duty PPC engine

This paper presents a numerical investigation of the ignition and combustion process of a primary reference fuel in a partially premixed light-duty internal combustion (PPC) engine. Partially pre-mixed combustion is achieved by employing a multiple injection strategy with three short injection events of fuel pulses. The timing of the first two fuel pulses, 48 and 22 crank angle degrees before top

Årscykel bisyssla

Sektionen HR har tagit fram ett universitetsgemensamt stöd i form av en årscykel för bisyssla. Genväg:Ta del av årshjulets olika steg i löptext Årscykelns olika stegJanuariUppstart årlig anmälningsskyldighet för lärare – under första kvartalet.Information till prefekter och lärare om att bisyssla ska anmälas senast 31 mars. Hantering av anmälningar och eventuella beslut om upphörande av bisyssla.F

https://www.hr-webben.lu.se/arscykel-bisyssla - 2026-05-19

Relationship of the Hormone-Sensitive Lipase-Mediated Modulation of Cholesterol Metabolism in Individual Compartments of the Testis to Serum Pituitary Hormone and Testosterone Concentrations in a Seasonal Breeder, the Mink (Mustela vison).

The role of cholesterol differs in the two compartments of the testis. In the interstitial tissue, cholesterol is necessary for the synthesis of testosterone, whereas in the seminiferous tubules, membrane cholesterol content in developing germ cells will influence the gametes' fertility. Here we evaluate the hormone-sensitive lipase (HSL) modulation of the cholesterol metabolism in each compartmen

Expression, activity, and subcellular localization of testicular hormone-sensitive lipase during postnatal development in the guinea pig

The present work reports on testicular hormone-sensitive lipase (HSL), the biological significance of which has been documented in male fertility. The HSL protein levels and enzymatic activity were measured, respectively, by densitometry of immunoreactive bands in Western blots, performed with antibodies against recombinant rat HSL, and by spectrophotometry in seminiferous tubules (STf) and inters

Yves Bourdet

Associate professor Contact details Email: yves [dot] bourdet [at] nek [dot] lu [dot] se Phone: +46 72 233 10 64 Mobile: +46 72 233 10 64Organisation Department of Economics Service point: 10 WebpageYves Bourdets profile in Lund University research portal Publications Displaying of publications. Sorted by year, then title. Filter by type AllBookBook chapterJournal articleJournal article reviewRepo

https://www.lusem.lu.se/yves-bourdet - 2026-05-19

Five homologous repeats of the protein G-related protein MIG cooperate in binding to goat immunoglobulin G

Protein MIG, from Streptococcus dysgalactiae, binds alpha2-macroglobulin and immunoglobulin G (IgG). MIG-derived fusion proteins with one to five IgG-binding repeats differed up to 72,000- fold in avidity for goat IgG, indicating a considerable cooperativity of the repeats. Significant sequence variation in the IgG-binding repeats was recognized. Protein MIG interacted with goat IgG1 via both the

Multilevel survival analysis of health inequalities in life expectancy

Background: The health status of individuals is determined by multiple factors operating at both micro and macro levels and the interactive effects of them. Measures of health inequalities should reflect such determinants explicitly through sources of levels and combining mean differences at group levels and the variation of individuals, for the benefits of decision making and intervention plannin