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N-glycans and the N terminus of protein C inhibitor affect the cofactor-enhanced rates of thrombin inhibition

Protein C inhibitor (PCI) is a serine protease inhibitor, displaying broad protease specificity, found in blood and other tissues. In blood, it is capable of inhibiting both procoagulant and anticoagulant proteases. Mechanisms that provide specificity to PCI remain largely unrevealed. In this study we have for the first time provided a full explanation for the marked size heterogeneity of blood-de

No Slide Title

No Slide Title Is child L2 French like 2L1 or like adult L2? Suzanne Schlyter & Jonas Granfeldt Lund University IASCLXI, Edinburgh, 28th July to 1st August Questions If there is a qualitative difference between (2)L1 and adL2 acquisition, at what age is the cut-off point? (5, 4, 3 … years?) To what extent do early successive bilinguals differ from 2L1 children and adult and older child L2 learners

https://projekt.ht.lu.se/fileadmin/user_upload/sol/ovrigt/projekt_sprakutv_franska/Edinburgh_08_Schlyter.ppt - 2026-05-30

No title

Course literature MHIA22: Media History: Level 2, (30 ECTS) spring 2023 Department of Communication and Media, Lund University Established by the board of the Department of Communication and Media, Lund University, 1 December 2022. Module 1: Digital history: Media and methods in theory and practice Also free-standing course MHIA25 Agostinho, Daniela (2019). “Archival Encounters: Rethinking Access

https://www.historiska.lu.se/media/utbildning/dokument/kurser/MHIA25/20231/LL_MHIA25_spring_2023.docx - 2026-05-31

Antibody-dependent allostery of the M1 protein

Den förrädiska antikroppen Streptokocker är en lömsk bakterie som har många olika sätt att ta sig runt vårt immunförsvar. Den kan låtsas vara en del av vår kropp genom att klä sig själv i en proteinkapsel som är väldigt likt ett mänskligt protein, bryta ned våra celler med hjälp av utsöndrade gifter och använda vårt immunförsvar mot oss genom att binda antikroppar till sig själv. En virulensfaktoThe Group A streptococcus (GAS) (Streptococcus pyogenes) is a significant human pathogen known for causing a diverse range of diseases, spanning from mild diseases such as pharyngitis to life-threatening diseases such as necrotizing fasciitis. Its virulence comes from a plethora of immune evasion mechanisms, but the M protein with its hypervariable region and ability to bind human proteins, stands

AMDS.GlOW36

AMDS.GlOW36 Language Faculty, Complexity Reduction and Symmetry Breaking Anna Maria Di Sciullo, Université du Québec à Montréal 1. I assume that the Language Faculty is stable, it does not vary though time and space, and that language development requires experience (Chomsky 1995, 2005, 2011). I develop the view that language evolutionary development is the result of the interaction of the languag

https://konferens.ht.lu.se/fileadmin/user_upload/sol/ovrigt/konferens_glow36/Biolinguistics/Language_Faculty__Complexity_Reduction_and_Symmetry_Breaking.pdf - 2026-05-30

Tobias Biermann

Research engineer Contact details Email: tobias [dot] biermann [at] mgeo [dot] lu [dot] se Phone: +46 46 222 67 57 Mobile: +46 70 795 02 39Organisation Department of Earth and Environmental Sciences (MGeo) Visiting address: Sölvegatan 12, Geocentrum 2, Lund Room number: 429 Service point: 16 WebpageTobias Biermanns profile in Lund University research portalOther affiliations Research engineer ICOS

https://www.nateko.lu.se/tobias-biermann - 2026-05-30

Luf fyrviks webb

Sid 6 Connect with your past – and form the future Lund University Foundation is a non-profit organization, based in the United States. The foundation operates ex- clusively for charitable, scientific and educational purpo- ses. Our mission is to strengthen Lund University’s ties with the United States and with Lund alumni by raising funds from donors in the United States and making grants availab

https://www.lu.se/sites/www.lu.se/files/luf_fyrviks_webb.pdf - 2026-05-31

Purification of streptococcal protein G expressed by Escherichia coli by high performance liquid affinity chromatography using immobilized immunoglobulin G and albumin

A one-step HPLC method was developed for the purification of protein G, a cell wall molecule from group C and G streptococci with immunoglobulin G- and albumin-binding properties. Lysed Escherichia coli bacteria infected with lambda-phages containing the protein G gene from group G streptococci were used as a starting material for the preparations. The lysate was applied to a column with immobiliz

Antibodies specific for the antigenic domain 1 of glycoprotein B (gpUL55) of human cytomegalovirus bind to different substructures

Glycoprotein B (gB, gpUL55) is a major antigen for the induction of neutralizing antibodies against human cytomegalovirus, making it an attractive antigen for active and passive immunoprophylaxis. The immunodominant region on gB is the antigenic domain 1 (AD-1), a complex structure which requires a minimal linear amino acid sequence of more than 75 amino acids (aa 552-635) for antibody binding. We

Comparison of Surface Properties of Human IgA, IgE, IgG and IgM Antibodies with Identical and Different Specificities

In this paper, the authors report the use of liquid-liquid partition chromatography (LLPC) in an aqueous polyethylene glycol (PEG)/dextran two-phase system to compare the surface properties (partition properties) of human antibodies and fragments thereof. The surface properties of all the monoclonal antibodies of different classes and subclasses investigated were within the same broad range as tha

Oral treatment with a vitamin D3 analogue (BXL628) has anti-inflammatory effects in rodent model of interstitial cystitis

To investigate the effects of a vitamin D3 analogue (BXL628) in a model of chronic cystitis, as calcitriol analogues might be an interesting new therapeutic option for interstitial cystitis, for although the cause of the disease remains unclear, the increase in mast cells in the mucosa and detrusor muscle are significant. We devised a mouse model of allergen-induced allergic cystitis that is assoc

Från förening till företag - Sportslig kontra ekonomisk framgång

Syftet med uppsatsen är att undersöka vad framgång är i dagens skandinaviska elitfotbollsklubbar och vilka strategier som är användbara för att uppnå denna. Uppsatsen ämnar således belysa och klargöra de viktigaste aspekterna i en lyckad strategi inom en modern skandinavisk fotbollsklubb. Med denna kunskap har vi för avsikt att återge en bild över hur en elitfotbollsklubb strategiskt bör organiser

Methane and carbon dioxide fluxes over a lake : Comparison between eddy covariance, floating chambers and boundary layer method

Freshwaters bring a notable contribution to the global carbon budget by emitting both carbon dioxide (CO2) and methane (CH4) to the atmosphere. Global estimates of freshwater emissions traditionally use a wind-speed-based gas transfer velocity, kCC (introduced by Cole and Caraco, 1998), for calculating diffusive flux with the boundary layer method (BLM). We compared CH4 and CO2 fluxes from BLM wit

Polygenic pathways shape white matter vulnerability to Alzheimer’s disease-related pathophysiological changes

Background: The accumulation of amyloid-β1−42 (Aβ1−42) peptides and phosphorylated-Tau181 (p-Tau181) tangles from the preclinical stages of Alzheimer’s disease (AD) has led to a biological definition of the disease. However, among Aβ1−42-positive individuals, cognitive decline onset varies, and some never develop symptoms. Genetic influences on molecular pathways and their interactions with protei

Redox control of exocytosis - Regulatory role of NADPH, thioredoxin, and glutaredoxin

Cellular redox state is an important metabolic variable, influencing many aspects of cell function like growth, apoptosis, and reductive biosynthesis. In this report, we identify NADPH as a candidate signaling molecule for exocytosis in neuroendocrine cells. In pancreatic beta-cells, glucose acutely raised the NADPH-to-NADP(+) ratio and stimulated insulin release in parallel. Furthermore, intracel

20250415-Hybrid CoE Paper-24-WEB (1)

Hybrid CoE Paper 24 Social identities and democratic vulnerabilities: Learning from examples of targeted disinformation Elsa Hedling – April 2025 Hybrid CoE Papers are finalized pieces of analysis on a topic related to hybrid threats, based on one or several research questions. They may be either conceptual analyses or based on a concrete case study with empirical data. The European Centre of Exce

https://www.psychologicaldefence.lu.se/sites/psychologicaldefence.lu.se/files/2025-04/20250415-Hybrid_CoE_Paper-24-WEB%20(1).pdf - 2026-05-31