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Objective: A liquid mepolizumab formulation in a single-use prefilled syringe (PFS) is under development. We evaluated the usability of mepolizumab self-injected via PFS by patients with severe eosinophilic asthma (SEA), or their caregivers, in clinic and at home. Methods: This open-label, single-arm, Phase IIIa study included patients with SEA, aged ≥12 years, and receiving mepolizumab (100 mg su
The Øresund Basin in the transnational area between Sweden and Denmark forms a marginal part of the Danish Basin. The structural outline and stratigraphy of the Mesozoic succession is described, and a novel interpretation and description of the subsurface geology and geothermal potential in the North Sjælland Half-graben is presented. The subsurface bedrock in the basin includes several Mesozoic i
PURPOSE: Despite the increasing burden of cancer occurred over recent years in the African continent, epidemiologic data from Northern Africa area have been so far sparse or absent. We present most recently available data from the Benghazi Cancer Registry concerning cancer incidence and mortality as well as the most comprehensive survival data set so far generated for cases diagnosed during 2003 t
Split Vision Urbanism HK is a design research project located at the intersection of urban governance, architectural design, and media arts. It seeks to critically address the relationship between formal and informal structures in order to uncover the hidden potentials of porous urban space, extracting new territories for design practices to engage the generative aspects of high density. Drawing o
Every year about 15 million people are injured in traffic, 500,000 of these fatally. Developing countries are badly affected. During the worst years of the war in Nicaragua, more people died in traffic accidents than as a direct result of the war. Transport system and infrastructure have developed rapidly in developing countries, while little has been achieved in preventing accidents or lessening
While several scholars do not consider the anointing of (the feet of) Jesus in Bethany described in the Gospel of John to carry any messianic connotations, some claim that a royal messianic notion is behind the anointing. The hypothesis of this paper is that the anointing is indeed to be understood as messianic, but that it is insufficient to consider only one Christological motif to be in the bac
EF-hand proteins are central in many cellular processes being the main group of Ca2+-sensing and buffering proteins in the cell. In the work presented in this thesis we study ligand interactions of three EF-hand proteins; calmodulin, calbindin D28k and secretagogin. We have developed a screening method using proteins arrays and validation of targets with surface plasmon resonance. With have applie
Flexible manufacturing puts high demands on industrial automation in terms of affordable and competitive solutions and is of key importance for short-lot production typically found in small and medium sized enterprises, situations where today manual labour is extensively used despite environmental issues and harsh working conditions. Key factors in the successful introduction of new robot automati
One of the common tools for studying the deformation behavior of the microstructure in polycrystalline materials is crystal plasticity models. These are used to describe texture evolution and hardening due to crystallographic slip. A drawback when using crystal plasticity models is that the calculation of the slip requires solving a set of stiff differential equations for each grain in the microst
This study focusses on the urban infrastructure for water supply in Roman Pompeii. The water distribution network of lead pipes was constructed inside the city walls, at the time when the city was connected to an aqueduct. Life for the Pompeiians changed considerably when aqueduct water started running continuously in street fountains all around the city. The study is based on previous research an
Keynote paper The point of departure for this lecture lies in the insight that tourism research is uniquely positioned at the juncture of applied and scholarly research. Drawing upon work I have conducted in the realms tourism and leisure study, the lecture strives to problematize the practice of ethnography as a method and raise questions concerning the opportunity research in the fields of tour
What makes some persons more prejudiced than others What makes some persons more prejudiced than others? Modeling the role of social dominance, empathy, social desirability, and gender. Martin Bäckström, Fredrik Björklund*, Sven B. Hansson, Dina Bern and Bert Westerlundh Department of Psychology, Lund University Structural equation modeling on questionnaire data showed that different kinds of prej
https://www.psy.lu.se/sites/psy.lu.se/files/vol6no2.pdf - 2026-07-22
Handbok för forskarutbildningen Handbok för forskarutbildningen LUNDS UNIVERSITET | SOCIALHÖGSKOLAN HANDBOK FÖR FORSKARUTBILDNINGEN Handboken för forskarutbildning i socialt arbete riktar sig till doktorander, handledare och andra verksamma vid Socialhögskolans forskarutbildning. Men den kan även vara använd- bar för den som överväger att söka till utbildningen eller utför uppdrag åt institutionen
https://www.soch.lu.se/sites/soch.lu.se/files/2026-01/Handbok_forskarprogrammet_sv%20jan-26.pdf - 2026-07-22
III-V semiconductors are a profound part of the optoelectronics industry and new developments in alloy compositions and architectures are constantly emerging. Lowdimensional semiconductors, such as nanowires (NWs) have shown to have improved characteristics in certain areas such as enhanced light absorption and can furthermore be integrated on Silicon (Si) plattforms and are thus predicted to be a
Migration is critical for life-cycle completion in diadromous fish species. River connectivity is vital in facilitating these large-scale movement events, but the extent of present-day river fragmentation can interfere with these migrations. Fish passage solutions (FPSs) are commonly implemented with the aim of improving river connectivity. In our study, we investigated the performance of two type
Due to the large-scale production of lignin, continuous flow reactors are preferred for its further valorization through depolymerization. However, there is limited literature on their use in lignin depolymerization, especially concerning feedstock pretreatments and catalyst deactivation. Therefore, in this study, the impact of a batch solvolysis pretreatment on the mild reductive catalytic depoly
Insulin stimulates fusion, but not tethering, of GLUT4 vesicles in skeletal muscle of HA-GLUT4-GFP transgenic mice. Am J Physiol Endocrinol Metab 302: E950-E960, 2012. First published January 31, 2012; doi:10.1152/ajpendo.00466.2011.-Insulin regulates glucose uptake into fat and muscle by modulating the subcellular distribution of GLUT4 between the cell surface and intracellular compartments. Howe
