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The Faculty of Science's website is part of Lund University's web and uses the same publishing system. The central web unit is responsible for the system and the technical aspects while the Faculty of Science is responsible for the content. Processing of personal dataLund University processes personal data in accordance with the EU's General Data Protection Regulation (GDPR) 2016/679, the Data Pro

https://www.science.lu.se/internal/about-site - 2026-05-31

Results of a phase I/II study of ocrelizumab, a fully humanized anti-CD20 mAb, in patients with relapsed/refractory follicular lymphoma

Background: Ocrelizumab is a humanized anti-CD20 antibody with increased antibody-dependent cellular cytotoxicity compared with rituximab. This phase I/II study evaluated its safety and efficacy in patients with relapsed/refractory follicular lymphoma (FL) after prior rituximab therapy. Design and methods: Forty-seven patients were treated in three dose cohorts and received eight infusions every 3

Streptococcus pyogenes secreted enzymes interacting with the human host

Streptococcus pyogenes is one of the most common bacteria infecting humans. One of the factors contributing to the disease-causing properties is the secreted streptococcal cysteine proteinase, SpeB, which degrades several host proteins in connective tissue and circulation. SpeB activity depends on the transformation from an inactive precursor, zymogen, into a mature proteinase. We show that

Potentialities of manganese ore and iron-carbon particles for pharmaceuticals and personal care products removal in electroactive constructed wetland

This study explores the use of manganese ore, iron-carbon particles (Fe-C), and gravel as anode fillers in electroactive constructed wetlands (ECWs) to treat wastewater containing pharmaceuticals and personal care products (PPCPs) including ciprofloxacin (CIP), ofloxacin (OFL), and naproxen (NPX), while also assessing bioelectricity production. Although the presence of PPCPs reduced pollutant remo

Development and validation of a novel Simoa assay for NPTX2 in Alzheimer's disease and Down syndrome

INTRODUCTION: Synaptic dysfunction and loss are pathological hallmarks of neurodegenerative diseases. Neuronal pentraxin 2 (NPTX2), a presynaptic protein involved in synaptic plasticity, has been linked to cognitive decline in Alzheimer's disease (AD) and other neurodegenerative disorders. METHODS: We developed and validated a novel single molecule array (Simoa) for NPTX2 in cerebrospinal fluid, w

Structural determination of Streptococcus pyogenes M1 protein interactions with human immunoglobulin G using integrative structural biology

Streptococcus pyogenes (Group A streptococcus; GAS) is an important human pathogen responsible for mild to severe, life-threatening infections. GAS expresses a wide range of virulence factors, including the M family proteins. The M proteins allow the bacteria to evade parts of the human immune defenses by triggering the formation of a dense coat of plasma proteins surrounding the bacteria, includi

Efficacy of T-cell assays for the diagnosis of primary defects in cytotoxic lymphocyte exocytosis

Primary hemophagocytic lymphohistiocytosis (HLH) is a life-threatening disorder associated with autosomal recessive variants in genes required for perforin-mediated lymphocyte cytotoxicity. A rapid diagnosis is crucial for successful treatment. Although defective cytotoxic T lymphocyte (CTL) function causes pathogenesis, quantification of natural killer (NK)–cell exocytosis triggered by K562 targe

Text For Course Site English

Applied Statistics III: Regression Analysis 3 credits (half-time) Dates:  November 6 – December 1, 2023 Course content and aim:  The course provides the participants with in-depth knowledge of different methods in regression analysis and how these methods can be applied in medical research. The course consists of the following five themes: · Introduction to theory and methods of regression analysi

https://www.intramed.lu.se/sites/intramed.lu.se/files/2023-05/Text%20for%20course%20site%20English.docx - 2026-06-01

06032016 679 40 kemppainen diab care 2014

Early Childhood Gut Microbiomes Show Strong Geographic Differences Among Subjects at High Risk for Type 1 Diabetes Diabetes Care 2015;38:329–332 | DOI: 10.2337/dc14-0850 OBJECTIVE Gut microbiome dysbiosis is associated with numerous diseases, including type 1 diabetes. This pilot study determines how geographical location affects themicro- biome of infants at high risk for type 1 diabetes in a pop

https://www.teddy.lu.se/sites/teddy.lu.se/files/06032016_679_40_kemppainen_diab_care_2014.pdf - 2026-06-01

Manual lymphatic drainage for lymphedema following breast cancer treatment

Background More than one in five patients who undergo treatment for breast cancer will develop breast cancer-related lymphedema (BCRL). BCRL can occur as a result of breast cancer surgery and/or radiation therapy. BCRL can negatively impact comfort, function, and quality of life (QoL). Manual lymphatic drainage (MLD), a type of hands-on therapy, is frequently used for BCRL and often as part of com

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The purpose of this dissertation is to examine to what extent the dramatic work of Bernard-Marie Koltès could serve as a basis for ethical reflections. The main object of the study is Koltès' construction of his characters by certain narrative techniques embedded in the dramatic structure and energizing the interpersonal conflicts. By telling their past and expressing their future prospects, the p

Vägledning Uppgiftsfördelning Uppdaterad 250204

Brevmall Vägledning till ifyllande av uppgiftsfördelning inom arbetsmiljö- och brandskyddsarbete Fördelad arbetsmiljöuppgift Förtydligande information Läs mer här 1. Planera, organisera, genomföra och följa upp verksamheten så att denna bedrivs i enlighet med de krav som ställs på arbetsmiljö för anställda och studenter i lagar och föreskrifter, Lunds universitets arbetsmiljöpolicy, avtal, styrand

https://www.hr-webben.lu.se/sites/hr-webben.lu.se/files/2026-01/V%C3%A4gledning%20Uppgiftsf%C3%B6rdelning%20uppdaterad%20250204.pdf - 2026-06-01

Energy Storage & Conversion

Sustainable energy storage and conversion explores innovative methods to efficiently store and transform energy from various renewable sources. It focuses on technologies like advanced batteries, hydrogen production, fuel cells, and thermochemical systems as well as safety aspects of battery storage systems. Research aims to enhance energy density, reduce costs, and improve scalability, enabling r

https://www.energy.lth.se/research/energy-storage-conversion - 2026-05-31