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Identification of subjects with a high risk of developing type 2 diabetes (T2D) is fundamental for prevention of the disease. Consequently, it is essential to search for new biomarkers that can improve the prediction of T2D. The aim of this study was to examine whether 5 DNA methylation loci in blood DNA (ABCG1, PHOSPHO1, SOCS3, SREBF1, and TXNIP), recently reported to be associated with T2D, migh
Material traceability is an important part of industrial manufacturing, especially in systems where quality, reliability, and documentation requirements are high. In many companies, traceability is often assumed to already exist because there are certificates, ERP systems, production documents, and established routines. However, during this study, it became clear that having information available
This thesis investigates how existing urban environments can be adapted to strengthen climate resilience and improve everyday access to urban rest within dense cities. Urban rest is understood as restorative conditions within the everyday urban environment, where opportunities for pause, recovery, and social interaction can occur across both public and semi-private spaces. The thesis identifies an
Purpose: The study aimed to investigate the associations between impaired spirometry such as obstructive pattern and preserved ratio impaired spirometry (PRISm) and occurrent cardiovascular events and deaths in patients with acute myocardial infarction. Patients and Methods: Cohort study of 517 patients with age ≥40 years and ≥10 pack-years of smoking, hospitalized for myocardial infarction at eig
This thesis examines how Swedish legal and administrative frameworks governing LKAB’s mining operations have historically produced and reproduced the invisibility of Sámi land use, and how these patterns of exclusion continue to be mobilized within contemporary green transition justifications. Drawing on settler colonial theory and anopticism, the study argues that Sámi exclusion within Swedish re
Bokslut för jämställdhets-, likabehandlings- och mångfaldsarbete År 2013 Institutionen för service management och tjänstevetenskap _________________________________________________ Institutionernas handlingsplan ska utgå från Fakultetens handlingsplan för jämställdhet, likabehandling och mångfald under 2012 (DnrS2011/315) och ange de konkreta åtgärder som kommer att vidtas i institutionens systema
https://www.ses.lu.se/sites/ses.lu.se/files/jlm-bokslut_ism_2013.pdf - 2026-07-09
Slide 1 Avfallsförebyggande i den privata sektorn Inget försvinner allt bara sprids 22 January 2010 29 januari 2015 Incitament för avfallsförebyggande Den privata sektorn: Består av organisationer, företrädelsevis företag, som drivs i vinstsyfte Ekonomi Avfallsminimering kan vara ett sätt att minska företagets kostnader genom minskad användning av resurser och onödiga inköp. Miljö Avfallsminimerin
https://www.ses.lu.se/sites/ses.lu.se/files/peter_johansson_sem2_aff_privata_sektorn.pdf - 2026-07-09
Kursutvärdering kursnamn Sida 1 av 3 Centrum för miljö- och klimatvetenskap Grund- och avancerad utbildning KURSANALYS Datum Kursansvarig: Katarina Hedlund Antal studenter: 52 Antal svar: 27 Betyg: 5 G och 45 VG Kursanalys: Miljövetenskap Grundkurs MVEA10 höstterminen 2021 Sammanfattning av kursvärderingen Studenterna har nått mycket bra resultat och 50 av 52 har avklarat kursen helt. De har nått
https://www.cec.lu.se/sv/sites/cec.lu.se.sv/files/2022-05/Kursanalys%20MVEA10%20HT21.pdf - 2026-07-09
Type 1 conventional dendritic cells (cDC1s) are rare immune cells critical for the induction of antigen-specific cytotoxic CD8+ T cells, although the genetic program driving human cDC1 specification remains largely unexplored. We previously identified PU.1, IRF8, and BATF3 transcription factors as sufficient to induce cDC1 fate in mouse fibroblasts, but reprogramming of human somatic cells was lim
Methylenetetrahydrofolate dehydrogenase/cyclohydrolase (MTHFD2) is a new drug target that is expressed in cancer cells but not in normal adult cells, which provides an Achilles heel to selectively kill cancer cells. Despite the availability of crystal structures of MTHFD2 in the inhibitor- and cofactor-bound forms, key information is missing due to technical limitations, including (a) the location
Objective: Immediate cartilage structural alterations in the acute phase after an anterior cruciate ligament (ACL) rupture may be a precursor to posttraumatic osteoarthritis (PTOA) development. Our aim was to describe changes in cartilage matrix in the subacute phase of the acutely ACL-injured knee compared to the contralateral uninjured knee. Design: Participants (n = 118) aged 15–40 years with a
Gestational diabetes mellitus (GDM) is associated with increased risk of pregnancy complications and adverse perinatal outcomes. GDM often reoccurs and is associated with increased risk of subsequent diagnosis of type 2 diabetes (T2D). To improve our understanding of the aetiological factors and molecular processes driving the occurrence of GDM, including the extent to which these overlap with T2D
The interaction of protein S with membranes and subsequent combination with complement C4b-binding protein (C4BP) was studied. Protein S interacted with phospholipid vesicles in a calcium-dependent manner typical of other vitamin K-dependent proteins. Association of C4BP with protein S showed no apparent selectivity for membrane-bound or solution phase protein S. When bound to the membrane, the pr
Introduction: Primary health care centers (PHCCs) in Sweden are struggling to maintain a balance between increasing demands of service and supervision and learning activities for a growing number of students. We sought a deeper understanding of primary care physicians and managers behavioral intention towards supervising, and their perceptions of the structural preconditions and support needed.Met
Neurotensin (NT) is a small protein implicated in the regulation of energy balance which acts as both a neurotransmitter in the central nervous system and as a gastrointestinal peptide. In the gut, NT is secreted after fat ingestion and promotes the absorption of fatty acids. The circulating levels of its precursor, pro-NT, predicts the presence and development of metabolic and cardiovascular dise
Biological aerosol particles affect human health, are essential for microbial and gene dispersal, and have been proposed as important agents for atmospheric processes. However, the abundance and size distributions of atmospheric biological particles are largely unknown. In this study we used a laser-induced fluorescence instrument to measure fluorescent biological aerosol particle (FBAP) concentra
