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Both genetic and lifestyle factors contribute to the risk of non-alcoholic steatohepatitis (NASH). Additionally, epigenetic modifications may also play a key role in the pathogenesis of NASH. We therefore investigated liver DNA methylation, as a marker for epigenetic alterations, in individuals with simple steatosis and NASH, and further tested if these alterations were associated with clinical ph
Nitrogen (N) cycle dynamics and N deposition play an important role in determining the terrestrial biosphere's carbon (C) balance. We assess global and biome-specific N deposition effects on C sequestration rates with the dynamic global vegetation model LPJ-GUESS. Modeled CN interactions are evaluated by comparing predictions of the C and CN version of the model with direct observations of C fluxe
PURPOSE: Gitelman's syndrome (GS) is an inherited autosomal recessive disorder due to loss of function mutations in the SLC12A3 gene encoding the Na-Cl co-transporter (NCCT), the target of thiazide diuretics. The defective function of the NCCT, which normally is expressed in the apical membrane of the distal convolute tubule in the kidney, leads to mild hypotension, hypokalemia, hyperreninemic hyp
Researcher Contact details Email: zhendong [dot] wu [at] mgeo [dot] lu [dot] seOrganisation Department of Earth and Environmental Sciences (MGeo) Service point: 16 WebpageZhendong Wus profile in Lund University research portalOther affiliations Member of Strategic Research Area eSSENCE: The e-Science CollaborationMy research applies a dynamic global vegetation model (LPJ-GUESS) to investigate ques
https://www.nateko.lu.se/zhendong-wu - 2026-07-20
Senior lecturer Contact details Email: elsa [dot] trolle_onnerfors [at] jur [dot] lu [dot] se Phone: +46 46 222 10 97Organisation Department of Law Room number: 332 Service point: 56 WebpageElsa Trolle Önnerfors profile in Lund University research portalOther affiliations Researcher Legal history Associate professor Department of Law Publications Displaying of publications. Sorted by year, then ti
https://www.law.lu.se/elsa-trolle-onnerfors - 2026-07-20
Master’s Thesis Project Topic 01 - LEO Group (Autumn 2024) Title: Improved Operational Sentinel-2 BRDF Correction for Enhanced Land Surface Estimation The current Bidirectional Reflectance Distribution Function (BRDF) correction for high-resolution vegetation remote sensing products (e.g., HLS, Claverie et al. 2018) is primarily based on the simplified method developed by Roy et al. (2016, 2017),
https://www.nateko.lu.se/sites/nateko.lu.se/files/2024-09/Master%20thesis%20project%20topics.docx - 2026-07-21
Sid 1Sid 5 Så här stödjer du Botan vid Lunds universitet Du kan enkelt stödja Botaniska trädgården vid Lunds universitet genom gåvor i valfri storlek. Bidrag betalas till plusgiro 5 89 93 -7 eller bankgiro 830-6599. Vi tar även tacksamt emot månatliga gåvor, minnesgåvor, högtidsgåvor, julgåvor och företagsgåvor. Alla bidrag, oavsett storlek, är lika välkomna. Märk din gåva med “Botan”. Ange även a
https://www.lu.se/sites/www.lu.se/files/botan.pdf - 2026-07-21
Manuskriptideer Kursutvärdering GEOL01, Kandidatarbete,VT 2016 19 studenter av totalt 24 lämnade in den utskickade kursvärderingen. Nedan följer en sammanfattning av resultatet från kursvärderingen: Markera det alternativ som bäst stämmer överens med vad du tycker (1= håller inte alls med -- - 5=håller fullständigt med) Jag är nöjd med den här kursen. Antal svar: 1 0 (0,0%) 2 1 (5,3%) 3 3 (15,8%)
https://www.geologi.lu.se/sites/geologi.lu.se/files/geol01_kursvardering_2016_2.pdf - 2026-07-21
Denna uppsats behandlar de konkurrensrättsliga skillnaderna i EU-rätt och amerikans rätt rörande patentpooler. Genom patentpooler ges företag möjlighet att gemensamt samla sina patent inom ett visst tekniskt område och tillsammans licensera dem. Genom poolning av patent ökar möjligheterna för snabb utveckling samtidigt som licenskostnaderna minskar då samtliga nödvändiga patent blir tillgängliga gThis thesis identifies the differences in the antitrust regulations concerning patent pooling within the EU and the U.S. Patent pooling enables firms to jointly licence their patents as a package, gathering patents that are necessary in order to produce a certain product. Patent pooling allows faster development at lower costs, since firms can attain all necessary patents through one single licens
Streptococcus pyogenes can cause invasive disease with high mortality despite adequate antibiotic treatments. To address this unmet need, we have previously generated an opsonic IgG1 monoclonal antibody, Ab25, targeting the bacterial M protein. Here, we engineer the IgG2-4 subclasses of Ab25. Despite having reduced binding, the IgG3 version promotes stronger phagocytosis of bacteria. Using atomic
F(ab) fragments imprinted surface plasmon resonance (SPR) chip was prepared for the real-time detection of human immunoglobulin G (IgG). In order to attach polymerization precursor on SPR chip, the SPR chip surface was modified with allyl mercaptan. F(ab) fragments of the IgG molecules were prepared by papain digestion procedure and collected by fast protein liquid chromatography (FPLC) system usi
Most of the recombinant proteins produced nowadays are fused to affinity tags, in order to facilitate their purification through affinity chromato-graphy. Out the different tags available, poly-histidine tags are among the most commonly used and can help purification through immobilised metal ion affinity chromatography (IMAC). In this thesis, we present different metal binding tags, and their af
