Filtyp
Preclinical data suggest that chronic stress may cause cellular damage and mitochondrial dysfunction, potentially leading to the release of mitochondrial DNA (mtDNA) into the bloodstream. Major depressive disorder has been associated with an increased amount of mtDNA in leukocytes from saliva samples and blood; however, no previous studies have measured plasma levels of free-circulating mtDNA in a
The protein alpha-synuclein is central to the pathophysiology of Parkinson's disease (PD) but its role in the development of neurodegeneration remains unclear. alpha-Synuclein-knockout mice develop without gross abnormality and are resistant to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP), a mitochondrial inhibitor widely used to model parkinsonism. Here we show that differentiated human do
Background: The EsPhALL2004 randomised trial showed a 10% advantage in disease-free survival for short, discontinuous use of imatinib after induction compared with no use of imatinib in patients with Philadelphia chromosome-positive acute lymphoblastic leukaemia receiving Berlin-Frankfurt-Münster chemotherapy and haemopoietic stem-cell transplantation (HSCT). Other contemporary studies showed an a
We recently presented a new method for quantification of CArdiac FUnction - denoted CAFU - as the first step in the development of an automated method for integrated interpretation of gated myocardial perfusion single photon emission computed tomography (SPECT) images. The aim of this study was to validate CAFU in the assessment of global and regional function of the left ventricle. Quantitative g
Importance: Lack of arachidonic acid (AA) and docosahexaenoic acid (DHA) after extremely preterm birth may contribute to preterm morbidity, including retinopathy of prematurity (ROP).Objective: To determine whether enteral supplementation with fatty acids from birth to 40 weeks' postmenstrual age reduces ROP in extremely preterm infants.Design, Setting, and Participants: The Mega Donna Mega trial,
This volume provides a comprehensive discussion and overview of urban resilience, including socio-ecological and economic hazard and disaster resilience. It provides a summary of state of the art thinking on resilience, the different approaches, tools and methodologies for understanding the subject in urban contexts, and brings together related reflections and initiatives.Throughout the different
Introduction: The use of pharmacokinetic assessment for optimal prophylactic dosing of factor concentrates in haemophilia has gained increasing enthusiasm over the last decade. However, blood sampling on several occasions is burdensome and limited sampling using population-based PK is appealing. Aim: To compare the pharmacokinetics and dosing recommendations for prophylaxis using six-point single
Background: Potato late blight caused by the oomycete pathogen Phytophthora infestans can lead to immense yield loss. We investigated the transcriptome of Solanum tubersoum (cv. Desiree) and characterized the secretome by quantitative proteomics after foliar application of the protective agent phosphite. We also studied the distribution of phosphite in planta after application and tested transgeni
Although many efforts have been made to eliminate barriers in public transport worldwide, research shows that public transport is still often perceived as challenging, inconvenient, and inaccessible for many people with disabilities. A growing body of research points to several issues, relating to the spatial and temporal distribution of public transport, affordability, safety, and social barriers
OBJECTIVE: To determine the effects of oxygen therapy in myocardial infarction (MI) patients with and without diabetes. RESEARCH DESIGN AND METHODS: In the Determination of the Role of Oxygen in Suspected Acute Myocardial Infarction (DETO2X-AMI) trial, 6,629 normoxemic patients with suspected MI were randomized to oxygen at 6 L/min for 6-12 h or ambient air. In this prespecified analysis involving
Family accommodation (FA) is widely-recognised as an important clinical phenomenon in obsessive–compulsive disorder (OCD) and anxiety disorders, and is related to poorer treatment outcomes. However, FA has not been quantitatively explored in Body Dysmorphic Disorder (BDD). The aim of this study was to investigate the patterns and correlates of maternal accommodation in adolescent BDD, and its asso
Research on microplastics in Latin America is limited compared to a global perspective. Brazil plays a significant role in this context, as it possesses 12% of the world’s freshwater reserves, constituting 53% of South America’s water resources. There has been growing concern regarding the plastic pollution of the country’s freshwater systems in recent years. Therefore, this study investigated the
Age and aging are the major determinants of most common major diseases, including cardiovascular disease (CVD). With increasing age, the cardiovascular risk increases as well as frailty, with negative consequences for health such as coronary heart disease, stroke, peripheral arterial disease, and vascular dementia. However, this aging process seems to take a more rapid course in some individuals,
Lending conditions LUND UNIVERSITY LIBRARIES Lending conditions in brief • Loans can be made to persons with a Swedish personal identity number or coordination number, who are over 18 years of age. • Guest students or –researchers must show a letter of acceptance or certificate of affiliation, to get a library card at Lund University Libraries. • You must always be prepared to show your library ca
https://www.lub.lu.se/en/sites/lub.lu.se.en/files/lanevillkor_2017_eng_webb-2.pdf - 2026-07-16
Schema för KURSNAMN 10 p (15 ECTS) VT -2 2003 Schema för GEOB03 , 15 högskolepoäng (15 ECTS credits) VT-2 2016 Litosfären Kursansvarig: Anders Scherstén (Dk 1) & Charlotte Möller (Dk2) Lärare: (in the order of appearance): Dk1: Anders Scherstén (AS), Carl Alwmark (CA), Sanna Holm (SH), Charlotte Möller (CM) Dk 2: Charlotte Möller (CM), Ashley Gumsley (AG), Leif Johansson (LJ) SI-mentorer: E-post t
https://www.geologi.lu.se/sites/geologi.lu.se/files/geob03_uppdaterat_schema_2016.pdf - 2026-07-16
Lending conditions LUND UNIVERSITY LIBRARIES Lending conditions in brief • Loans can be made to persons with a Swedish personal identity number or coordination number, who are over 18 years of age. • Guest students or –researchers must show a letter of acceptance or certificate of affiliation, to get a library card at Lund University Libraries. • You must always be prepared to show your library ca
https://www.lub.lu.se/en/sites/lub.lu.se.en/files/2021-03/L%C3%A5nevillkor%202021%20eng%20webb.pdf - 2026-07-16
BACKGROUND: Oxidative stress and related DNA damage in human sperm may be important for fecundity and pregnancy outcome. METHODS: We studied the level of oxidative DNA damage in terms of 7-hydro-8-oxo-2'-deoxyguanosine (8-oxodG) in sperm DNA among 225 first-pregnancy planners. Over the six menstrual cycle follow-up time, after cessation of contraception, 135 pregnancies were conceived. RESULTS: Th
The freeze-drying tolerance of Pseudomonas chlororaphis, an antifungal bacterium used as biocontrol agent was investigated. P. chlororaphis is freeze-drying sensitive and the viability drops more than 3 log units in the absence of protective freeze-drying medium. Of the freeze-drying media tested, lactose, sucrose, trehalose, glutamate, sucrose with glutamate, skimmed milk, and skimmed milk with t
AbstractPhysical exhaustion can constrain human ascending work capacity and performance during emergency evacuation on stairs. The overall aim of this research was to explore and compare stair ascending capacities and physiological limitations during two different strategies: self-preferred pace in three different public stairways in the field, and controlled pace in a laboratory on a stair machin
Background: Early hospital arrival and rapid intervention for acute myocardial infarction is essential for a successful outcome. Several studies have been unable to identify explanatory factors that slowed decision time. The present study examines whether personality, psychosocial factors, and coping strategies might explain differences in time delay from onset of symptoms of acute myocardial infa
