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The leukemia associated ETO nuclear repressor gene is regulated by the GATA-1 transcription factor in erythroid/megakaryocytic cells

BACKGROUND: The Eight-Twenty-One (ETO) nuclear co-repressor gene belongs to the ETO homologue family also containing Myeloid Translocation Gene on chromosome 16 (MTG16) and myeloid translocation Gene-Related protein 1 (MTGR1). By chromosomal translocations ETO and MTG16 become parts of fusion proteins characteristic of morphological variants of acute myeloid leukemia. Normal functions of ETO homol

Regional GDP estimates for Sweden, 1571-1850

This paper provides regional GDP estimates for the 24 Swedish regions (NUTS-3) for the benchmark year 1571 and for 11 ten-year benchmarks for the period 1750-1850. The 1571 estimates are based on tax sources and agricultural statistics. The 1750-1850 estimates are produced following the widely used methodology by Geary and Stark (2002): labour force figures from population censuses at regional lev

Exchange of CO2 in Arctic tundra : Impacts of meteorological variations and biological disturbance

An improvement in our process-based understanding of carbon (C) exchange in the Arctic and its climate sensitivity is critically needed for understanding the response of tundra ecosystems to a changing climate. In this context, we analysed the net ecosystem exchange (NEE) of CO2 in West Greenland tundra (64°N) across eight snow-free periods in 8 consecutive years, and characterized the key process

Gyro Stabilization of a Positioning Unit

Mounting cameras on motorized objects has become possible in greater extent due to the emerging camera technology during the past few decades. This application could prove useful in several areas such as search and rescue operations, surveillance or even news monitoring. One hardship that this brings is the difficulty of keeping the camera unit stable while its setting is not. In the situations me

Disease susceptibility may be increased by accumulation of genetic variants in chromatin loops from disease-relevant cell-types

Genome-wide association studies (GWAS) have identified more than 50,000 SNP-trait associations. Most of these SNPs or genetic variants map to noncoding regions, known as or gene desserts. This makes it challenging to describe the mechanism by which the variant confers susceptibility to the trait. Increasingly, there is an interest in characterization and interpretation of the effect of non-coding

The role of the private sector in sustainable water management in Kazakhstan

The social and environmental impacts associated with corporate water use and discharge in Kazakhstan is historically high, and in certain watershed pose a significant threat to the health of the local communities and ecosystems. Today the industries are consuming almost a third of freshwater and remain one of the biggest polluters in the country. The situation is aggravated with the changing clima

The Journey to Entrepreneurship: A Cultural Analysis of Creative Entrepreneurs in a Business Incubator in Finland

This thesis explores the process of becoming a creative entrepreneur and how this process can be supported in and out of an incubator. Using ethnographic methods and cultural analysis, I argue that being an entrepreneur is an overarching lifestyle and the process of becoming one is affected by each individual’s backgrounds, motivations, identities, existing skills, social networks and perceptions

Brandteknisk riskvärdering av Terminal 4, Arlanda

Arlanda flygplats är en av Nordens största flygplatser, vilket gör att personbrandskyddet är väldigt viktigt. Ett platsbesök genomfördes på Terminal 4 på Arlanda vid projektets början i syfte att göra en brandteknisk riskvärdering av byggnaden. Under platsbesöket samlades information in om potentiella riskkällor och möjligheterna att utrymma undersöktes. Detta resulterade i flera potentiella brand

A Bicriteria Simulated Annealing Algorithm for Scheduling Jobs on Parallel Machines with Sequence Dependent Setup Times

The study considers the scheduling problem of identical parallel machines subject to minimization of the maximum completion time and the maximum tardiness expressed in a linear convex objective function. The maximum completion time or makespan is the date when the last job to be completed leaves the system. The maximum tardiness is indicated by the job that is completed with the longest delay rela

Will plastic ever go away? : an analysis of how social movements can shift the framing of the plastic issue from consumption reduction to production as the driver of the plastic problem in Taiwan

Globally, the production and consumption of plastic has increased exponentially. As plastic items are produced using fossil fuels, the plastic industry is intrinsically tied to the petrochemical industry. One unique case of this dilemma lies in the petrochemical industry’s role in plastic production in Taiwan. Despite its reputation for recycling, Taiwan is satiated with ineffective sustainability

Otillbörlig påverkan - en studie av begreppet otillbörlig påverkan och dess betydelse för domstolens bedömning av barnets bästa

I vårdnad, boende och umgängesmål ska domstolen ta hänsyn till barnets vilja, som ett led i bedömningen av barnets bästa. Bedömningen försvåras dock ibland av att barn uttrycker sig på ett sätt som egentligen inte representerar deras verkliga vilja. Vad de uttrycker är istället ett resultat av påverkan från en förälder. Att barn i viss mån påverkas av sina föräldrar när de separerar är oundvikligtIn court cases concerning custody, residence and the child’s visitation rights to a parent, an assessment of what lies in the best interest of the child is made. According to the Parental Code, the court must consider the will of the child in order to make a proper assessment. However, the assessment is complicated by the fact that, sometimes, what children express is inconsistent with their actua

A Concept for an Intrusion Detection System over Automotive Ethernet

A modern automotive vehicle is a complex technical system, containing many electronic, mechanical, and software parts. Typically, a high-end vehicle contains 70 or more electronic control units (ECUs) on average. These are controlling a large number of distributed functions, of which many are safety-critical, and adding complexity, which is surpassing 100 million lines of code. Furthermore, the co

Evaluation of emergency ordering policies at Syncron

The aim of our research has been to identify what prevents Syncron from implementing a single item emergency ordering policy in their inventory management system, GIM. Emergency ordering is defined here as the ability to use two supply sources, a normal one and a faster more expensive emergency source. We further wanted to investigate under what circumstances an emergency ordering policy could be

Dina åsikter spelar roll - En kvalitativ studie av konsumentrecensioner online

Examensarbetets titel: Dina åsikter spelar roll - En kvalitativ studie av konsumentrecensioner online Seminariedatum: 2015-01-15 Ämne/kurs: FEKH29, Examensarbete kandidatnivå i marknadsföring, 15 HP Författare: Jens Boström, Denis Maliqaj och Bobo Tiger Handledare: Clara Gustafsson Fem nyckelord: Konsumentrecensioner online, e-WOM, CCT, Gemenskaper, Informationsdelning vid konsumtion. Syfte:Title: Your opinions matter - A qualitative study of consumer reviews online. Seminar date: 2015-01-15 Course: FEKH29, Degree Project in Marketing Undergraduate Level, 15HP Authors: Jens Boström, Denis Maliqaj and Bobo Tiger Advisor: Clara Gustafsson Key words: Online consumer reviews, e-WOM, CCT, Online Communities, Information sharing regarding consumption. Purpose: The purpose of this stu

Socialsekreteraren - En kvalitativ studie om faktorer som påverkar valet till att påbörja arbetet som barn- och ungdomsutredare inom socialtjänsten

You have seen it in the news, you have seen it in the papers. The situations for social workers in child protection are bursting. Turnovers, though work environment and low payments are things social-workers daily has to receive. Still there is few of them who starts to work at this workplace. Our question is why? In the following study, the aim is to analyze what factors are affecting their choic

Cannabisbruk och rättfärdigande på nätet

The goal of this study is to find out if participation in an Internet forum can help participants in that Internet forum justify an illegal use of cannabis. Today the most commonly used narcotic in Sweden is Cannabis (CAN 2012). Still, the drug has remained illegal over many years and the Swedish drug policy remains restrictive towards drug use. This paper uses Howard S. Bcker’s three forms of soc

Ett värdigt liv som funktionshindrad - En analys om rätten att leva som alla andra

År 1994 trädde Lagen om stöd och service till vissa funktionshindrade (1993:387) (LSS) som ett resultat av regeringens utredning. Utredningen, som fick namnet Handikappreformen, kom fram till att det fanns stora klyftor mellan människor med omfattande funktionshinder och människor utan funktionshinder. Dessutom noterade utredningen att de insatser som erhölls enligt socialtjänsten och hälso- och sIn 1994, the Swedish law on certain disabled persons, came into effect as a result of the government’s inquiry. The inquiry was named “Handikappreformen” (in english: The Disability reform). The reform revealed disparities between individuals with disabilities and those without disabilities. Furthermore, the inquiry noted that the support received through social services and healthcare was insuffi

Framtidsfullmakter i praktiken - Blev det som tänkt?

I samband med att användningen av framtidsfullmakter har skett över tid, så har det uppkommit frågor kring om hur framtidsfullmakterna fungerar i praktiken och om de fyller den funktion som lagstiftaren avsett. Lag (2017:310) om framtidsfullmakter, LFF, antogs 2017 i syfte att fungera som ett komplement till det existerande systemet med godmans- och förvaltarskap enligt föräldrabalken, FB, (1949In connection with the development of legal practice regarding future powers of attorney in recent years, some questions have been raised about whether the use of the power of attorney works in practice. In 2017, the Act (2017:310) on future powers of attorney, LFF, was adopted with the aim of functioning as a complement to the existing system of guardianship and trusteeship in the parental code,

Use and misuse of PLFA measurements in soils

The determination of the phospholipid fatty acid (PLFA) pattern of soil organisms has become one of the most commonly used methods to study microbial community structure. Here we recapitulate the background of our work applying the PLFA method to soil in the early 1990s. We also stress that although the PLFA method was, and still is, a rapid and sensitive method to detect changes in the microbial