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Cervical dystonia is a neurological movement disorder causing abnormal posture of the head. It may be accompanied by involuntary movements which are sometimes tremulous. The condition has marked effects on patients' self-image, and adversely affects quality of life, social relationships and employment. Botulinum neurotoxin (BoNT) is the treatment of choice for CD and its efficacy and safety have b
This report summarises our efforts in deriving, characterising and banking of 20 different human embryonic stem cell lines. We have derived a large number of human embryonic stem cell lines between 2001 and 2005. One of these cell lines was established under totally xeno-free culture conditions. In addition, several subclones have been established, including a karyoptypical normal clone from a tri
Popular Abstract in Swedish Övergripande syfte Syftet med avhandlingen var att utvärdera hur en förenklad metod för diagnostisering av blodproppar i benets djupa ådror (djup ventrombos (DVT)) fungerar i svensk rutinsjukvård. Den förenklade metoden innebär användning av en strukturerad klinisk sannolikhetsbedömning tillsammans med ett blodprov (D-dimer test). Vi jämförde också vår D-dimermetod med The combination of pre-test clinical probability assessment and D-dimer test is now widely applied in the diagnostic process of DVT. The general objective of the present investigation was to validate these results in a Swedish routine emergency setting were the prevalence of the disease is high and were the clinical probability assessment was handled by many junior physicians. Furthermore, our aim
The growth of epitaxial graphene on SiC has been identified as one of the most promising techniques to produce graphene for electronic applications. In this paper, we present a systematic study of the electronic and structural properties of large-area quasifree standing epitaxial monolayer graphene grown on top of the SiC(0001) surface. For this purpose, we combine the thermal treatment of SiC in
A report produced by the Swedish Building Commission, pointed out that high costs and poor quality exists in the construction industry. With the goal of getting a more effective building process NCC Construction AB implemented a new production control system. NCC calls the system NCC Project Planning (Swedish: NCC Projektplanering) and it is based on the Last Planner System, a system for planning
Conceptually, this paper is about the becoming of states and how such states are a socially constructed spaces, imagined and performed by those who perceive themselves as belonging to that state. It asks through what imaginaries and performative practices does a state come into being? More specifically, the paper investigates how the state is imagined and performed in times of war and peace hoping
We explore the multiphase structure of the circumgalactic medium (CGM) probed by synthetic spectra through a cosmological zoom-in galaxy formation simulation. We employ a Bayesian method for modelling a combination of absorption lines to derive physical properties of absorbers with a formal treatment of detections, including saturated systems, and non-detections in a uniform manner. We find that i
Aim: This study aimed to compare the quality of life (QoL) of cancer patients, with an Eastern Cooperative Oncology Group (ECOG) performance of 3-4, in contact with or without contact, with a specialized palliative care unit (PCU) at a low-resource governmental cancer hospital, as well as studying the impact of this contact on the QoL in their caregivers. Materials and Methods: Hospitalized patien
Most models explaining polygyny in birds have concentrated on variation in male or territorial quality, ignoring the role of females in maintaining monogamy. Although field observations have suggested that already mated females may maintain monogamy by either behaving aggressively toward prospecting females or by interupting male mate attraction behaviour, no experiments have been done to test if
Objective: The objective of this study was to evaluate attachment and its association to obstetric and demographic factors as well as emotional well-being using a standard measure of prenatal attachment during pregnancy. Background: The strength of the mothers’ relationship with her baby has important implications in the postnatal period, influencing the relationship she develops with her child, a
Objectives/Hypothesis: Data from patients registered for myringoplasty during 2002 to 2012 in the Swedish National Quality Registry for Myringoplasty. Study Design: Both conventional myringoplasty and fat-graft techniques were used aimed at healing the tympanic membrane in noninfected ears. Methods: Analysis was performed on data in a national database collected from 32 ear, nose, and throat clini
Upcycling is a process in which used or waste products and materials are repaired, reused, repurposed, refurbished, upgraded and remanufactured in a creative way to add value to the compositional elements. It has been part of human life throughout history, and the past few years have seen its revival, driven by multiple factors including growing concern for the environment and resource scarcity. U
Background andAims Middle-Eastern immigrants constitute a growing proportion of the Swedish population and are at high risk for Type 2 diabetes. This calls for a more proactive preventive approach for dealing with diabetes risk in this target group. The aim was to test the effect of a culturally adapted lifestyle intervention programme on changes in lifestyle habits and cardio-metabolic outcomes c
Objectives Regulations heavily control medical technology (MT), which often includes information technology (IT), but staff experiences related to these regulations are unknown. The study aim was to assess Swedish IT/MT staff experiences regarding regulations for medical devices and medical information systems. Methods An anonymous, ten-item, self-report questionnaire was administered to IT and MT
The goal of our research is the construction of efficient Jacobian-free preconditioners for high order Discontinuous Galerkin (DG) discretizations with implicit time integration. We are motivated by three-dimensional unsteady compressible flow applications, which often result in large stiff systems. Implicit time integrators overcome the impact upon restrictive CFL conditions on explicit ones but
Context. Homochirality is a generic and unique property of life on Earth and is considered a universal and agnostic biosignature. Homochirality induces fractional circular polarization in the incident light that it reflects. Because this circularly polarized light can be sensed remotely, it can be one of the most compelling candidate biosignatures in life detection missions. While there are also o
At least 30% of main sequence stars host planets with sizes of between 1 and 4 Earth radii and orbital periods of less than 100 days.We use N-body simulations including a model for gas-assisted pebble accretion and disk–planet tidal interaction to study the formation of super-Earth systems.We show that the integrated pebble mass reservoir creates a bifurcation between hot super-Earths or hot-Neptu
The impact of fires on humans and the environment has been the subject of investigation for decades. We have a variety of more or less well developed models to study the impact of fires on humans and even have several international standards categorising standardised approaches to quantifying the toxic potency of fire gas exposure. However, there is currently no standardised approach available to
