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This article provides an analysis on how disruptive innovation is spurred by the dynamics of digital and analogue networks in the sharing economy. The analysis builds on a free guided tour company in Copenhagen. Data is collected in a bottom-up reiterative process, drawing on theories on disruptive innovation and network theory. Between 2013 and 2016, one of the free tour companies in Copenhagen w
For over 30 years GIS has been a major theme in archaeology, leading scholars to debate the way geo-spatial platforms can contribute to a better understanding of the ancient landscape and a more thorough interpretation of the archaeological record. Recently, the introduction of more advanced software and hardware solutions have made it possible to use GIS for visualizing and analysing even geometr
Stroke is a significant cause of long-term disability, impairing over 10 million peoples motor function, primarily on one side of the body every year. Whilst effective rehabilitation exercises can help recover and maintain some affected motor function, stroke survivors often do not carry out enough of these. Instead relying on their `good' side to carry out tasks. However, this leads to poor recov
There is growing evidence of ongoing changes in the statistics of intra-seasonal rainfall variability over large parts of the world. Changes in annual total rainfall may arise from shifts, either singly or in a combination, of distinctive intra-seasonal characteristics -i.e. rainfall frequency, rainfall intensity, and rainfall seasonality. Understanding how various ecosystems respond to the change
PURPOSE: To assess and compare the costs of first-line monoclonal antibodies (mAbs) treatment protocols in breast cancer, non-Hodgkin lymphoma and colorectal carcinoma in South-Eastern Europe.METHODS: A retrospective, bottom-up case series study design was implemented with one-year time horizon and payer's perspective. The study sample size was 265 patients (breast cancer, N=137; colorectal cancer
Health promotion has become a widespread concept, although little empirical research as to its importance and outcome has been performed in the mental health field. The aim of the present study was to investigate the construct validity of a newly developed Health Promotion Intervention Questionnaire, intended to measure patients' subjectively experienced health-promoting interventions within menta
Popular Abstract in Swedish Forskningen som presenteras i denna avhandling fokuserar på tillverkning av små strukturella enheter (komponenter) samt tillämpning av ny teknologi för att adressera viktiga medicinska forskningsfrågeställningar. Framtagande av teknologi som använder sig av komponenter som är tusentals gånger mindre än bredden på ett hår är svårt men möjligt. Denna avhandling fokuserar This thesis focuses on the study of thin-film sensor technologies, novel microfabrication technologies, and thin-film technology in general. The work discusses electrochemical sensors and mechanical sensor technologies as well as fabrication strategies for them. Also included are mechano-chemical studies of the vancomycin DAla (Bacteria membrane analogue motif ) binding reaction in different chemica
We compared the Q10 relationship for root-derived respiration (including respiration due to the root, external mycorrhizal mycelium and rhizosphere microorganisms) with that of mainly external ectomycorrhizal mycelium and that of bulk soil microorganisms without any roots present. This was studied in a microcosm consisting of an ectomycorrhizal Pinus muricata seedling growing in a sandy soil, and
The structures of films of SP-B and mixtures of SP-B and DPPC at the air/water interface have been studied by neutron reflectometry (NR) and Langmuir film balance methods. From the film balance studies we observe that at very high pressures the isotherms of pure DPPC and SP-B/DPPC mixtures very nearly overlay one another, suggesting that the SP-B is being excluded from the film. The use of multipl
One of many important features of blue-green infrastructure is the ability to lower flood risks by detention of stormwater. This ability of flood risk reduction has for the first time been evaluated with empirical data in this study. In 2014, Malmö, Sweden, was hit with extreme precipitation corresponding to a return period of 50–200 years that led to severe pluvial flooding. This and other large
Popular science summaryMycorrhizal associations Mycorrhizal fungi are organisms that live in association with plant roots and provide plants with water and nutrients in exchange for the sugars obtained during photosynthesis. In forested ecosystems mycorrhizal fungi are crucial for tree nutrition and trees rely heavily on these associations to take up key elements like nitrogen and phosphorus. As rHigh levels of nitrogen (N) deposition might result in a transition from N to phosphorus (P) limitation in high latitude forests. Thiscould have fundamental consequences for forest production, nutrient acquisition and nutrient leaching.I studied a Norway spruce forest in a region of high N deposition in southwest Sweden and added N, P or N+P to force thesystem to N or P limitation. I studied tree
Innovation in retailing is under-investigated in academia and yet a highly relevant concern given the current changes in the retail landscape. Although retailing is often characterized by a dynamic and highly competitive environment, retail organi- zations are not often considered as ‘innovative,’ at least when compared with manufacturing industries, or when using exist- ing innovation frameworks
Intracerebral haemorrhage and small vessel ischaemic stroke (SVS) are the most acute manifestations of cerebral small vessel disease, with no established preventive approaches beyond hypertension management. Combined genome-wide association study (GWAS) of these two correlated diseases may improve statistical power to detect novel genetic factors for cerebral small vessel disease, elucidating unde
We have investigated strained GaAs-GaInP core-shell nanowires using transmission electron microscopy and nanofocused scanning X-ray diffraction. Nominally identical growth conditions for each sample were achieved by using nanoimprint lithography to create wafer-scale arrays of Au seed particles. However, we observe large individual differences, with neighboring nanowires showing either straight, b
Lead-based perovskite nanocrystals (NCs) have outstanding optical properties and cheap synthesis conferring them a tremendous potential in the field of optoelectronic devices. However, two critical problems are still unresolved and hindering their commercial applications: one is the fact of being lead-based and the other is the poor stability. Lead-free all-inorganic perovskite Cs3Bi2X9 (X=Cl, Br,
Public health care systems face major challenges. The burden of resource constraints and continuous demands of rationings urge decision makers in countries like Sweden, Norway and the UK to find new financial solutions. One proposal that has been put forward is co-payments. In this presentation we explore ethical problems associated with co-payments in publicly funded health care systems. The issuPublic healthcare systems face major challenges. The burden of resource con-straints and continuous demands of rationings urge decision makers in countries like Sweden, Norway and the UK to find new financial solutions. One proposal that has been put forward is co-payment, where patients are given the option to pay the public healthcare provider for additional care, or more e
Disasters and climate change impacts, as well as increased water demand, pose serious risks to the provision of sustainable urban water services, e.g., drinking water, sanitation, and safe drainage, especially in cities. These challenges call for a transition toward improved water management, including considerations of “resilience.” However, because the resilience concept has multidisciplinary or
Roma and Travellers (”resande”) have been present in Sweden for centuries. In the 19th and early 20th centuries, rural municipalities (kommuner) often adopted policies aimed to expel them from or to prevent them from entering the municipality. This is well established by previous research. What is less known is that another kind of territorial exclusion existed as well: that of collective violence
The family of galectin proteins involved in adhesion, growth regulation, immunity, and inflammatory events are important targets for development of small molecule antagonists. Here, N-sulfonyl amidine galactopyranoside derivatives obtained via a multicomponent reaction between galactose alkyne derivatives, sulfonyl azides, and amines were evaluated as antagonists of galectin-1,-2,-3,-4N (N-termina
