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This thesis deals with the dynamical processes in atoms and small molecules initiated by the absorption of ultrashort, coherent light pulses. The studied phenomena takeplace on the femtosecond (1 fs = 10−15 s) and attosecond (1 as = 10−18 s) timescales and critically depend on the properties of the light fields that drive them. Wework with infrared (IR) femtosecond laser pulses, which we manipulat
The overall aim of this thesis is to examine how walking as a transport mode is constructed in the planning realm, affected by the built environment and perceived by the individual. This aim is related to the following research questions: (1) How are pedestrians and walking understood, constructed and perceived in the planning context? (2) How does individual traits and the built environment affec
Normal birth is a eustress reaction, a beneficial hedonic stress with extremely high catecholamines that protects us from intrauterine hypoxia and assists in the rapid shift to extrauterine life. Occasionally the cellular O2 requirement becomes critical and an O2 deficit in blood (hypoxemia) may evolve to a tissue deficit (hypoxia) and finally a risk of organ damage (asphyxia). An increase in H+ c
Background: Immunohistochemical (IHC) PD-L1 expression is commonly employed as predictive biomarker for checkpoint inhibitors in triple-negative breast cancer (TNBC). However, IHC evaluation methods are non-uniform and further studies are needed to optimize clinical utility. Methods: We compared the concordance, prognostic value and gene expression between PD-L1 IHC expression by SP142 immune cell
The thesis presented here delves into why dwell time delays for commuter trains occur, with a specific focus on the impact of boarding and alighting passengers. The overarching aim is to develop knowledge of how time delays arise to identify and describe potential ways in which dwell time delays can be reduced. In addition to this, a secondary aim is to identify how dwell times can be studied on a
BACKGROUND: Tuberculosis remains a leading infectious cause of death in resource-limited settings. Effective treatment is the cornerstone of tuberculosis control, reducing mortality, recurrence and transmission. Supporting treatment adherence through facility-based observations of medication taking can be costly to providers and patients. Digital adherence technologies (DATs) may facilitate treatm
the body of literature on institutional fragmentation and interlinkages has become quite extensive over the last 10-15 years, especially in global environmental governance research. This common ground and the merits of existing scholarly approaches notwithstanding, there are still major new conceptual, theoretical and empirical grounds to be explored. Conceptually, the literature could further go
Universities have become important components of the national innovation systems in innovation driven economies. To strengthen the university related flow of mainly technological knowledge into commercialized products many European countries have followed the American example and changed from an inventor-ownership system to a university-owned system (Genua & Rossi, 2011). Today most European c
Contemporary advancements in miniaturization of analytical systems have advantageously fostered development, automation, and hyphenation of a variety of sample preparation techniques. Among several downscaled extraction designs, porous synthetic polymeric membranes (such as flat sheet (FS) or hollow fiber (HF)) have been utilized for membrane-based extraction, separating two aqueous phases (as in
Climate change and atmospheric aerosols are a threat for human health and life. Reducing aerosol emissions would save human lives close to the aerosol source, but could lead to more death due to the implications of a warmer climate. Aerosol particles acting as cloud or ice nuclei can induce a change in cloud properties and thus indirectly induce a change in planetary albedo, which is considered th
Popular Abstract in Swedish ”Vi kommo överens om att möten innehålla alla livets möjligheter, och att en människa som levat mycket vet mycket om möten om hon alls vet någonting.” Så uttalar den kvinnliga huvudpersonen i Mannen vid min sida (1933) sin övertygelse efter mötet med älskaren. Denna avhandling fokuserar mötet i Elin Wägners trettiotalsromaner. Genom att analysera detta vill avhandlingsfThe aim of this present thesis is to present the Utopian scheme in Elin Wägner’s novels of the nineteen-thirties: Dialogen fortsätter (1932) (“The Dialogue Continues”), Mannen vid min sida (1933) (“The Man by my Side”), Genomskådad (1937) (“Unmasked”) and Hemlighetsfull (1938) (“Mysterious”). With her authorship Wägner was aiming for a new social order, a radical change, polväxling (a shift of pol
Popular Abstract in Swedish Med magnetkamera (magnetresonans, MR) kan utmärkt morfologisk information erhållas men tekniken är även användbar för funktionella studier. En funktionell tillämpning är att mäta perfusion (kapillära blodflöden). Perfusionsrelaterad information kan åskådliggöras på flera sätt med MR, ofta via signalförändringar orsakade av spårämnen eller kontrastmedel i blodet. Den teThe studies presented in this thesis concern the optimisation and evaluation of the dynamic susceptibility contrast magnetic resonance imaging (DSC-MRI) technique for the assessment of perfusion-related parameters of the brain, such as cerebral blood flow (CBF), cerebral blood volume (CBV) and mean transit time (MTT). Several methodological factors influence these measurements, for example, contra
Popular Abstract in Swedish Under de senaste årtiondena har vattenfärgen i många svenska sjöar och vattendrag ökat. Detta innebär att vattnet blir brunare, och detta fenomen benämns därför brunifiering. Brunifiering är inget unikt för Sverige, utan förekommer på åtskilliga ställen på norra halvklotet. Brunifieringen påverkar det akvatiska ekosystemet och vattnets potentiella samhällsnytta. Ur en eThe term brownification refers to the trend of increasing water color, i.e. the water becoming browner, which has been observed throughout the northern hemisphere over the last decades. Brownification has both ecological and societal implications. From an ecological point of view the impaired light climate may e.g. reduce aquatic primary production and affect predator-prey interactions within the
Popular Abstract in Swedish See attachment in related materialThe combustion engine is today the dominant technology for transportation of goods and people world-wide. Concerns for global warming, toxic exhaust emissions, as well as cost and availability of fuel have in recent years created incentives for technological evolution of combustion engines. More sophisticated engine instrumentation with additional degrees of freedom has been added to the engine de
Abstract in Uncoded languages Praegune kaitsejalatsite testimise standard (EN 344) kontrollib soojapidavuslikke omadusi vaid jalatsi ühes punktis, mõõtes temperatuuri muutust. Meetod, mis kasutab termilist jala mudelit, võimaldab mõõta jalatsi soojaisolatsiooni üheaegselt erinevates piirkondades ning ühtlasi ka jalatsi kui terviku soojaisolatsiooni. Selle uurimuse käigus arendati termilise jala mePresent standard on safety footwear (EN 344) checks the insulation only at one point in the shoes by means of measuring the temperature change. A method that uses thermal foot model allows to measure footwear insulation simultaneously at various locations and for whole footwear as well. In the present work the method of heated foot model was developed further. It is possible to simulate sweating a
When on September 15, 2008 the financial conglomerate Lehman Brothers files for bankruptcy – and with that ‘officially’ sparks off the international financial crisis – few would have anticipated the invasive effect this crisis would come to have on the professional and personal lives of many across the world. Today, this implosion remains a mere ‘blip’ in the universe of events that ensued. On c
Alla ryggradsdjur har ett immunförsvar vars funktion är att skydda oss mot mikroorganismer som kan orsaka sjukdom, såsom bakterier och virus. Dessa sjukdomsframkallande ämnen kallas patogener. Immunförsvaret behöver kunna skilja mellan proteiner som kommer från den egna kroppen och från patogener. Molekylerna som kodas av gener i major histocompatibility complex (MHC) har en viktig del i denna igeThe function of the vertebrate immune system is to enable recognition and elimination of microorganisms that can cause harm (pathogens). A key component in adaptive immunity is the major histocompatibility complex (MHC) that codes for molecules with antigen presentation function. There are two main types of MHC molecules, class-I (MHC-I) and class-II (MHC-II) and the focus of my thesis has been MH
Risk management is increasingly used in dam safety and includes risk analysis, risk evaluation and risk reduction. Structural Reliability Analysis (SRA) is a probabilistic methodology that may be used in the risk assessment process. SRA has been frequently used for calibration of partial factors in limit state design codes for structures (not dams). In a reliability analysis a mathematical descrip
Cerebral accumulation of amyloid-β is thought to be the starting mechanism in Alzheimer's disease. Amyloid-β can be detected by analysis of cerebrospinal fluid amyloid-β42 or amyloid positron emission tomography, but it is unknown if any of the methods can identify an abnormal amyloid accumulation prior to the other. Our aim was to determine whether cerebrospinal fluid amyloid-β42 change before am
This thesis is based on three different projects: 1) the epitaxial growth of nanowires using chemical beam epitaxy, 2) the study of electron transport through quantum dots and multiple quantum dots in nanowires at low temperature, and 3) the development of wrap gated nanowire field effect transistors. In the first part, a method of studying the diffusion of the source material on the substrate su
