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Context: The age-related decline in dehydroepiandrosterone (DHEA) levels is thought to be of importance for general and vascular aging. However, data on the association between DHEA and mortality are conflicting. Objectives: We tested the hypothesis that low serum DHEA and DHEA sulfate (DHEA-S) levels predict all-cause and cardiovascular disease (CVD) death in elderly men. Design, Setting, and Par

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Background: There are at least three broad conceptual models for the impact of the social environment on adult disease: the critical period, social mobility, and cumulative life course models. Several studies have shown an association between each of these models and mortality. However, few studies have investigated the importance of the different models within the same setting and none has been p

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In order to simplify and/or improve determination of glomerular filtration rate (GFR) the clearances of iohexol, 51Cr-EDTA and endogenous creatinine were simultaneously determined with different techniques in 21 anesthetized landrace pigs. Their GFR had been reduced to about 1/3 or less of normal GFR. After an intravenous bolus of the GFR markers, their plasma concentration curves were followed fo

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Objectives: First, to outline the theoretical and practical framework for geriatric rehabilitation in the Nordic countries and second, to survey the scientific medical publications for evidence-based geriatric rehabilitation. Methods: Brainstorming on geriatric rehabilitation in a working group of Nordic teachers in geriatric medicine. Papers on scientific programmes for geriatric rehabilitation f

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Aim. To study nurses' compliance to national guidelines (Sweden) for peripheral venous catheters and to establish the complication frequency connected to time in situ and bore size. Background. Worldwide, there are no standard peripheral venous catheters guidelines, and the need for elective replacement has been challenged. Furthermore, the time interval and need for elective change of peripheral

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BACKGROUND: There is conflicting evidence that traffic-related air pollution is a risk factor for allergic conditions. Few studies have investigated this in adults. In adults, a high proportion of asthma, rhinitis and eczema is triggered by non-allergic factors. We investigated traffic as a risk factor for allergic versus non-allergic asthma and rhinitis, and eczema, in adults. A questionnaire fro

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Background and Purpose-Genetic variation influences risk of intracerebral hemorrhage (ICH). Hypertension (HTN) is a potent risk factor for ICH and several common genetic variants (single nucleotide polymorphisms [SNPs]) associated with blood pressure levels have been identified. We sought to determine whether the cumulative burden of blood pressure-related SNPs is associated with risk of ICH and p

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Popular Abstract in Danish Genterapi er en attraktiv terapiform mod neurologiske lidelser som Parkinsons sygdom og epilepsi af flere grunde. Gener med en terapeutisk effekt kan introduceres lokalt ved præcise injektioner i det syge væv, hvor genproduktet kan frigives fra nerveceller i respons til aktivitet i det omgivende væv. Ved genterapi omgås den forhindring som blod-hjernebarrieren udgør, ligGene therapy is an attractive strategy for neurological disorders, such as Parkinson’s disease and epilepsy, for several reasons. Introduction of genes with a therapeutic potential can be achieved locally, by accurate injections in the compromised tissue, and release of a transgene therapeutic substance can be regulated by the surrounding host neural circuitry. The gene therapy approach circumvent

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Populärvetenskaplig sammanfattning: Kolcykeln är enkelt uttryckt den globala balansräkningen av kolets (C) förflyttning genom olika sfärer såsom mellan atmosfären och biosfären, således är kolcykeln av stor betydelse för mänsklighetens existens. Exempelvis har atmosfäriska koncentrationer av koldioxid (CO2) och metan (CH4) ökat de senaste 200 hundra åren på grund av mänskliga aktiviteter (till stoCarbon is central to our existence. It plays a fundamental role in the carbon cycle. Atmospheric concentrations of carbon dioxide (CO2) and methane (CH4) have been increasing for about two centuries as a result of human activities. The need to understand how carbon cycles through the Earth-system is important for a variety of reasons, but mainly in order to assess the effects of these rising green

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Föreliggande uppsats behandlar två omdiskuterade lagar, lagen med särskilda bestämmelser om vård av unga (LVU) respektive lagen om psykiatrisk tvångsvård (LPT). Det primära syftet är att utröna gränsdragningen i rättens kriterier för tvångsvård av den unge, dels enligt LVU, dels enligt LPT. I vilka fall tillämpas LVU respektive LPT för den unge? Jag försöker även belysa om det råder förenlighet meThis thesis deals with two very highly debated regulation concerning the Care of Young Persons Act (1990:52) and the Involuntary Psychiatric Care Act (1992:1128), hereafter referred to as the LVU and the LPT. The primary purpose of this thesis is to explore the factual boundaries put in place by the courts’ criteria for the involuntary care of young people in accordance with the LVU and the LPT. W

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Ovako Ajax me, in York, South Carolina, USA manufactures seamless steel rings. The rings are made from blocks, which are heated, pressed, punched and then rolled to desired size and shape. Due to tougher competition on the seamless steel ring market, it is necessary to know the total production time for an order of specific rings, in order to be able to price the rings correctly and plan the prod

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The purpose of this master thesis is to investigate the influencing factors of the busi-ness potential of products with health claims, using PrimaLiv as an example, and give recommendations on how a dairy producer, which is present in the Swedish market, could improve the sales rates of products with health claims. We have chosen to put a main focus on the consumers, since they determine the busin

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IntroductionAnal squamous cell carcinoma (ASCC) is an HPV-related tumor primarily treated with concurrent chemoradiotherapy (CRT). Salvage surgery is reserved for patients with residual or recurrent disease following CRT, representing a highly selected, high-risk subgroup. Population-based data on outcomes and prognostic factors after salvage surgery are limited. This study aimed to assess overall

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Ränteavdragsreglerna har alltsedan de infördes år 2009 varit föremål för kritik, exempelvis vad gäller deras förenlighet med de i FEUF fastslagna fria rörligheterna. Trots att HFD har konstaterat att ränteavdragsreglerna är förenliga med de fria rörligheterna kvarstår kritiken. Reglernas syfte är att skydda den svenska bolagsskattebasen genom att begränsa den generella avdragsrätten för ränteutgifEver since the rules limiting the deductibility of interest expenses for intra-group loans (the interest deduction rules) were first adopted in 2009, they have been subject to criticism, for example concerning their consistency with the four freedoms of the Treaty on the Functioning of the European Union. Even though the matter has been settled by the Supreme Administrative Court the criticism sti

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This research aims to fill the knowledge gap with regards to food waste prevention with a specific focus on quick service restaurants (QSRs) – also known as fast food restaurants. Restaurants are in a prime position to reduce food waste produced in the consumptive stages of the food supply chain, and more focus should be placed on how restaurants can help achieve food waste reduction targets. The

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This Master’s thesis is performed on behalf of Alfa Laval, a multinational company providing technological products and services.
Alfa Laval has in the past had a lot of successful mergers, but there were also those cases that led to sell off and those that had potential to add more value than was actually realized. In the common case, it has been shown that 60-70 per cent of M&As fall sho

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Begreppet barnets bästa är en av de fyra grundläggande principerna i Förenta Nationernas konvention den 20 november 1989 om barnets rättigheter, Barnkonventionen. Principen om barnets bästa återspeglas även inom utlänningsrätten och enligt 1 kap. 10 § utlänningslagen (2005:716) skall i fall som rör ett barn särskilt beaktas vad hänsynen till barnets hälsa och utveckling samt barnets bästa i övrigtOne of the four fundamental principles of the United Nations Convention of the Rights of a Child is that of devotion to the best interests of the child. This is written in the UNCRC Article 3 as “In all actions concerning children, whether undertaken by public or private social welfare institutions, courts of law, administrative authorities or legislative bodies, the best interests of the child sh

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Background: Accurate prehospital trauma triage is crucial for identifying critically injured patients and determining the level of care. In the prehospital setting, time and data are often scarce, limiting the complexity of triage models. The aim of this study was to assess whether, compared with logistic regression, the advanced machine learner XGBoost (eXtreme Gradient Boosting) is associated wi

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Purpose: The quantitative accuracy of Nuclear Medicine images, acquired for both planar and SPECT studies, is influenced by the isotope-collimator combination as well as image corrections incorporated in the iterative reconstruction process. These factors can be investigated and optimised using Monte Carlo simulations. This study aimed to evaluate SPECT quantification accuracy for 123I with both t