Filtyp
Trade-offs between immune function and other physiological and behavioural processes are central in ecoimmunology, but one important problem is how to distinguish a reallocation of resources away from the immune system from a reallocation or redistribution within the immune system. While variation in baseline values of individual immune parameters is well established, studies in wild animals on mu
Rhesus Rhadinovirus (RRV) is currently the closest known, fully sequenced homolog of human Kaposi's sarcoma-associated herpesvirus (KSHV). Both these viruses encode complement inhibitors: KSHV-complement control protein (KCP) and RRV-complement control protein (RCP). Previously we characterized in detail the functional properties of KCP as complement inhibitor. Herein, we performed comparative ana
The extraction procedure for analysis of the raffinose family oligosaccharides (RFOs) in blanched leguminous vine peas was optimized. For this purpose, 25 pea samples from different cultivars and of different maturity were chosen at random. The effect of blanching was also studied in four cultivars. The yield of oligosaccharides was almost double on average when extracted with 50% ethanol as compa
Partial preferences may occur due to differences in profitability and encounter probability between food types within a patch. In the expanding specialist diet strategy, a forager goes from being partially selective on the preferred, most profitable food, to being opportunistic, after the preferred food has been depleted to a certain critical level. We studied the diet selection strategies of bird
Background and purpose The remodeling of morselized bone grafts in revision surgery can be enhanced by an anabolic substance such as a bone morphogenetic protein (BMP). On the other hand, BMPs boost catabolism and might cause a premature resorption, both of the graft and of the new-formed bone. Bisphosphonates inactivate osteoclasts and can be used to control the resorption. We studied a combinati
Popular Abstract in Swedish De svenska framtidsuttrycken (futuralt presens, futuralt skola och futuralt komma) är alla kontextuellt betingade användningar av uttryck som också har andra funktioner. Syftet med min avhandling är att beskriva vilka kontextvillkor som måste vara uppfyllda för att de tre uttrycken ska fungera som framtidsuttryck. I den modell över svenskans temporala system som presentThe main aim of this study is to specify the contextual conditions that apply to the use of the three central expressions for the future in Swedish: the present form and the auxiliaries skola and komma. A tense suffix indicates a temporal domain and states that a mediating element, here called FIX, is placed in the indicated domain. The present suffix points to a domain that overlaps temporally wi
Four kitchens, each with a different work load, were used to evaluate the microbiological risk of utilizing blasting granules in a new type of warewash machine. The granules, plastic pellets 3.5 - 3.5 mm, are recirculated together with the dishwater in the machine, and when the dishwater is expelled, the granules remain in the machine until the next day. Samples of soiled dishwater and tap water w
Background: It is not known whether the recently described break in the trend in hip fracture incidence in many settings applies in both women and men, depends on changes in bone mineral density (BMD) or changes in other risk factors, or whether it is apparent in both urban and rural settings. Methods: We evaluated changes in annual hip fracture incidence from 1987 to 2002 in Swedish men aged >= 6
The overall aims of this work were to investigate if Deep Brain Stimulation in the subthalamic nuclei (STN) affected balance, fear of falling and falls in people with Parkinson's disease. The effect of STN stimulation alone was investigated in Papers I, II and III. The participants were evaluated after an overnight withdrawal of anti-PD medication and with the STN stimulation turned off and on. F
Purpose: To develop a system for refined motor control of artificial hands based on multiple electromyographic (EMG) recordings, allowing multiple patterns of hand movements. Methods: Five subjects with traumatic below-elbow amputations and 1 subject with a congenital below-elbow failure of formation performed 10 imaginary movements with their phantom hand while surface electrodes recorded the EMG
In clinical practice, blood volume flow (BVF) is typically calculated assuming a perfect parabolic and axisymmetric velocity distribution. This simple approach cannot account for the complex flow configurations that are produced by vessel curvatures, pulsatility and diameter changes and, therefore, results in a poor estimation. Application of the Womersley model allows compensation for the flow di
The splice variant INS-IGF2 entails the preproinsulin signal peptide, the insulin B-chain, eight amino acids of the C-peptide and 138 unique amino acids from an ORF in the IGF2 gene. The aim was to determine whether levels of specific INS-IGF2 autoantibodies (INS-IGF2A) were related to age at diagnosis, islet autoantibodies, HLA-DQ, or both, in newly diagnosed type 1 diabetes patients and controls
Popular Abstract in Swedish Förmågan att kunna hitta mat är väldigt viktigt för alla djur eftersom detta påverkar flera saker, t ex hur snabbt man växer. Det i sin tur påverkar vilken roll man har i en grupp, hur mycket energi man har råd att lägga på fortplantning och hur många ungar man får. Att söka mat är oftast för-knippat med att äta, men inkluderar även andra aspekter som att söka efter matThe foraging ability of an organism is essential since it affects various traits, e.g. growth, reproduction effort, social status and, ultimately, fitness. Foraging is often associated with food intake but includes more aspects such as searching for and assessing food patches and evaluating the patch as good or bad compared to the rest of the environment. On top of that, a forager also has to surv
Biomechanical models which require information on, e.g., joint torque and muscle force are useful in the estimation of when and how mechanical overload of the musculoskeletal system may lead to disorders. The aim was to study the reliability and validity of magnetic resonance imaging (MRI) to quantify muscle sizes and moment arms by MRI and to test selected anthropometric measures as predictors of
Popular Abstract in Swedish BAKGRUND Bukspottkörteln, pankreas, är ett organ med två huvudfunktioner. Dels bildar körteln ett flertal hormoner som framförallt styr sockeromsättningen och dels bildar pankreas ett bikarbonatrikt sekret som neutraliserar den sura magsaften i tolvfingertarmen och som innehåller förstadier (proenzym) till ett flertal enzym verksamma vid nedbrytning av födans beståndsdePancreatic enzymes, neutrophils, free radicals and cytokines are involved in the pathophysiology of AP. Clarification of their interaction and time-course will improve our understanding of AP and provide a better basis for treatment. 20% will develop severe AP and benefit from improved treatment why an accurate test for prediction of severity is needed. Aims: To investigate the interactions betwee
This thesis presents spin transport studies of ferromagnetic nano-scaled tunneling devices fabricated by atomic force microscopy (AFM) and electron beam lithography (EBL). The thesis covers three main topics: The first topic is a study of spin accumulation (relaxation) in Au nano-structures using Ni/Au/Ni ferromagnetic single electron transistors (F-SETs). A Ni/Au/Ni F-SET with a single central Au
Popular Abstract in Swedish Avhandlingen ger en överblick över dagens status inom nanoimprintlitografi. Teknologin ger möjlighet att framställa nm-strukturer med en upplösning bättre än 10 nm och kan användas för massproduktion av hela wafers. Avhandlingen beskriver utvecklingen av reproducerbara imprintprocesser som t.ex. kan användas för framställning av nm-strukturerade fingerelektroder. DessaThis thesis gives an overview about the current status of nanoimprint lithography, a relatively new nanofabrication tool. The technology is capable for parallel mass production of nm-structured features having a resolution below 10 nm and is usable with high throughput on full wafer scale. The thesis is mainly divided into two parts dealing with nanoimprint lithography and electrochemistry. The w
The prognostic impact of t(12;21)(p13;q22) [ETV6/RUNX1 fusion] in paediatric acute lymphoblastic leukaemia (ALL) has been extensively debated, particularly with regard to the frequency of late relapses and appropriate treatment regimens. We have retrospectively collected 679 ALLs with known ETV6/RUNX1 status, as ascertained by fluorescence in situ hybridization or reverse-transcription polymerase
The human DUSP15 gene encodes an uncharacterized 235-amino acid member of the subfamily of small dual specificity protein phosphatases related to the Vaccinia virus VH1 phosphatase. Similar to VHR-related MKPX (VHX) (DUSP22), the predicted protein has an N-terminal myristoylation recognition sequence, and we show here that both are indeed modified by the attachment of a myristate to Gly-2. In reco
