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OBJECTIVE: To evaluate the outcomes after fenestrated endovascular aortic repair (f-EVAR) in a tertiary European referral center. METHODS: All patients treated with commercially available custom-made f-EVAR between September 2002 and June 2007 were prospectively enrolled in a computerized database including co-morbidities and aneurysm morphology. Patients were retrospectively analyzed. Follow-up c
Abstract Individuals within species often show a consistent differences in their risk-taking behavior. I investigated whether intra-specific variation in risk-taking behavior is adaptive, i.e. if it stems from the life history strategy differences between individuals. As a result of life history trade-offs, individuals vary in their investment into survival and reproduction, such that some indivi
I den första sektionen av denna uppsats behandlas hur alkohol- och drogmissbruk inverkar på bedömningen av grund för uppsägning eller avsked. De lagbestämmelser som är aktuella i denna del finns framförallt i lagen om anställningsskydd, arbetsmiljölagstiftningen samt socialförsäkringsbalken. Sjukdom utgör som huvudregel inte saklig grund för uppsägning utan arbetsgivaren har en skyldighet att försThe first section of this essay addresses how alcohol or drug addiction affects whether the employer has the right to terminate the employment or dismiss the employee. Relevant regulations are mainly found in the Employment Protection Act, the Work Environment Act and the Social Insurance Code. The main rule is that the employment cannot be terminated due to a person’s sickness if the employer has
Aim: Virtual clinical trials (VCT) in medical imaging can be used to predict the outcome of clinical trials, by simulating anatomy, imaging methods and image interpretation. VCTs could reduce the cost and duration of clinical trials and their dependence on available patients. This thesis is motivated by the limitations in the field of breast cancer screening. The aim of the project is to expand a
Förstainstansrättens dom i målet Microsoft mot Kommissionen har gett upphov till många konkurrensrättsliga frågor, bl.a. gällande Microsofts tying av Windows Media Player till sitt operativsystem Windows. Denna uppsats för framförallt ett resonemang kring frågan om huruvida de ”traditionella” EG-rättsliga metoder som idag används vid bedömningen av kopplingsförbehåll (tying) är förlegade när dessa
This essay is devoted to quite a special form of investment - venture capital. More precisely the purpose is to map out, describe and analyse the most fundamental parts of investment protection in connection with venture capital investments. Venture capital is part of the market of risk capital, which refers to investments occuring on the receipt of, or possibility to receive ownership in a compan
IntroductionAn important hallmark of cancer is escaping the immune system. Despite advances in immunotherapy, only a subset of patients experiences clinical benefits. It was shown that adoptive T cell or checkpoint inhibition therapy rely on the presence of conventional dendritic cells type 1 (cDC1). cDC1 excel in recruiting and priming protective CD8+ T cells through cross-presentation. However,
Omstridda sexuella representationer har länge varit en konfliktyta i en västerländsk kontext. Vissa av dessa representationer har snabbt avfärdats som obscena, pornografiska, smutsiga, värdelösa eller ointressanta, medan andra har utmanat etablerade kategoriseringar och blivit föremål för intensiv debatt. För att undersöka och förstå de skriftliga sexuella representationernas historia i en svensk Transgressive sexual representations have long been a point of contention in Western societies. While some representations are easily disregarded as obscene, pornographic, smut, worthless or uninteresting, others disrupt established categorizations and are subject to heated debates. To map and understand the history of written, sexual representations in a Swedish context, I use the literature/porn
Objective: There is a lack of real-life studies on interleukin-17 (IL-17) inhibition in psoriatic arthritis (PsA). We assessed real-life 6- and 12-month effectiveness (i.e., retention, remission, low disease activity [LDA], and response rates) of the IL-17 inhibitor secukinumab in PsA patients overall and across 1) number of prior biologic/targeted synthetic disease-modifying antirheumatic drugs (
BackgroundLoss to follow-up (LTFU) from tuberculosis (TB) treatment and care is a major public health problem as patients can be infectious and also may develop a multi-drug resistant TB (MDR-TB). The study aimed to assess whether LTFU differs by the distance TB patients travelled to receive care from the nearest health facility.MethodsA total of 402 patient cards of TB patients who received care
BackgroundIt remains unclear as to why some individuals at low risk of cardiovascular disease (CVD) develop severe coronary atherosclerosis, while those at high CVD risk may remain free from coronary atherosclerosis.PurposeUsing Coronary Computed Tomography Angiography (CCTA), we aimed to identify factors associated with absence and severe coronary atherosclerosis in subjects from the general popu
Background and Objectives Structural brain MRI and blood-based phosphorylated tau (p-tau) measures are among the least invasive and least expensive Alzheimer's disease (AD) biomarkers to date. The extent to which these biomarkersmay outperformone another in predicting future Alzheimer dementia diagnosis is poorly understood, however. This study investigated 2 specific AD biomarkers, i.e., a cortic
OBJECTIVES: To investigate if socioeconomic status impacts patient-reported outcomes after a surgically treated trigger finger (TF).DESIGN AND SETTING: Data on patients with TF treated with surgery were collected from the Swedish National Quality Registry of Hand Surgery (HAKIR) 2010-2019 with an evaluation of symptoms and disability before surgery and at 3 and 12 months after surgery, using the s
Background and aims: Alcohol use disorder (AUD) is one of the strongest predictors of suicidal behavior. Here, we measured risk of suicide attempt and death as a function of AUD typologies. Design: We used AUD typologies from previous latent class analysis: (i) externalizing subtype (characterized by externalizing symptomatology and early age of onset; individuals in this group have lower educatio
OBJECTIVES: To explore broadened entry criteria of the 2021 European Resuscitation Council/European Society of Intensive Care Medicine (ERC/ ESICM) algorithm for neuroprognostication including patients with ongoing sedation and Glasgow Coma Scale-Motor score (GCS-M) scores 4–5. DESIGN: Retrospective multicenter observational study. SETTING: Four ICUs, Skane, Sweden. PATIENTS: Postcardiac arrest pa
Background: Violence due to firearms is a major global public health issue and vascular injuries from firearms are particularly lethal. The aim of this study was to analyse population-based epidemiology of firearm-related vascular injuries. Methods: This was a retrospective nationwide epidemiological study including all patients with firearm injuries from the national Swedish Trauma Registry (SweT
Background: Prostate cancer (PC) survivors may potentially use substances to cope with psychological distress or poorly controlled physical symptoms. Little is known, however, about the long-term risks of alcohol use disorder (AUD) or drug use disorders in men with PC. Methods: A national cohort study was conducted in Sweden of 180-189 men diagnosed with PC between 1998 and 2017 and 1 801 890 age-
Background Patients with acute intracerebral hemorrhage who are receiving factor Xa inhibitors have a risk of hematoma expansion. The effect of andexanet alfa, an agent that reverses the effects of factor Xa inhibitors, on hematoma volume expansion has not been well studied. Methods We randomly assigned, in a 1:1 ratio, patients who had taken factor Xa inhibitors within 15 hours before having an a
Background: Risky sexual behavior (RSB) is one of the major youth sexual and reproductive health problems globally, including in Ethiopia. RSB among youth increases the risk of HIV infection, other sexually transmitted infections (STIs), unintended pregnancy, and unsafe abortion. Therefore, the aim of this study was to examine RSB and its associated factors among university students in Ethiopia. M
