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In this study, we examined the onset and duration of local analgesic effects of bupivacaine incorporated into biodegradable microcapsules (extended-duration local anesthetic; EDLA) administered as subcutaneous infiltrations in different doses in humans. In 18 volunteers, the skin on the medial calf was infiltrated with 10 mL of EDLA, and the opposite calf was infiltrated with 10 mL of aqueous bupi
Among asthmatics, exercise-induced wheeze (EIW) is a frequent symptom, and 40-77% of asthmatics demonstrate exercise-induced bronchoconstriction (EIB). In the North-Trondelag population-based survey of 8,571 adolescents (YOUNG-HUNT), 26% reported wheeze during the previous 12 months (current wheeze). Of those subjects, 50% reported EIW. The aim of the present study was to investigate the associati
This non-randomized prospective controlled study evaluates a daily school-based exercise intervention program of 40 min/school day for I year in a population-based cohort of 81 boys aged 7-9 years. Controls were 57 age-matched boys assigned to the general school curriculum of 60min/ week. Bone mineral content BMC; g) and areal bone mineral density (aBMD; g/cm(2)) were measured with dual X-ray abso
PURPOSE: To describe complications and visual outcome of photocoagulation for clinically significant macular oedema. SUBJECTS AND METHODS: Evaluation of macular oedema and complications of photocoagulation in 194 eyes, defined as subretinal fibrosis, atrophic creep of the pigment epithelium and subretinal neovascularization was based on stereo fundus photo grading. The study included 25 patients w
Background: We have developed a rapid method, based on lamellar body counts (LBC) on gastric aspirate, for identifying newborns who will develop respiratory distress syndrome with a need for surfactant supplementation. Objective: We set out to test whether it was possible to improve the outcome when used in a clinical trial. Methods: We randomly assigned 380 infants born at 24-29 weeks' gestation
We examined how radiation dose levels in digital breast tomosynthesis (DBT) differ from those used in 2-view full-field digital mammography (FFDM). Acquisition parameter settings and information on the average absorbed dose to the glandular tissues within the breasts were reviewed based on clinical studies that evaluated DBT and FFDM. Dose ratios (DDBT/DFFDM) were derived from imaging protocols, w
Aims: To test if islet autoantibodies at diagnosis of type 1 diabetes (T1DM) and after 3-6 years with T1D predict residual beta-cell function (RBF) after 3-6 years with T1D. Methods: T1D children (n = 260, median age at diagnosis 9.4, range 0.9-14.7 years) were tested for GAD65, IA-2, ZnT8R, ZnT8W and ZnT8Q autoantibodies (A) at diagnosis, and 3-6 years after diagnosis when also fasting and stimul
Posterior laryngitis is a common cause of chronic cough, hoarseness, voice fatigue and throat pain. The aim of the present study was to examine how patients with posterior laryngitis have been examined, treated and followed up, and to assess their present health-related quality of life (HRQOL). Patients treated for posterior laryngitis at consultation at the ear-, nose- and throat clinic during 20
We have developed a new approach to create microsatellite primer sets that have high utility across a wide range of species. The success of this method was demonstrated using birds. We selected 35 avian EST microsatellite loci that had a high degree of sequence homology between the zebra finch Taeniopygia guttata and the chicken Gallus gallus and designed primer sets in which the primer bind sites
Background/Aim: Low-molecular-weight heparin (LMWH) has been shown to prolong survival among patients with solid tumors, but its role among myeloma patients is unknown. Patients: Data from the GIMEMA (Gruppo Italiano Malattie Ematologiche dell'Adulto), Nordic and Turkish myeloma study groups comparing melphalan and prednisolone with (MPT, n: 404) or without thalidomide (MP, n: 393) are analyzed fo
The aim of the study was to illuminate the families' lived experience after completing a child's cancer treatment. The study took place at a University Hospital in southern Sweden. Interviews were carried out with 10 mothers, eight fathers, four patients and two siblings from a total of 10 families. The interviews were analysed with a hermeneutical phenomenological approach. One essential theme em
This paper uses data from an observational study, conducted at access points in straight sections of primary roads in Malaysia in 2012, to investigate the effects of motorcyclists' behavior and road environment attributes on the occurrence of serious traffic conflicts involving motorcyclists entering primary roads via access points. In order to handle the unobserved heterogeneity in the small samp
Ljus består av elektromagnetiska vågor som pulserar genom universum med olika frekvenser. Vanligt ljus, som det som kommer från solen och från våra lampor, innehåller ett spektrum av många olika frekvenser. De olika vågornas toppar och dalar svänger inte heller i takt, utan är förskjutna i förhållande till varandra. I laserljus däremot, svänger alla vågor samtidigt upp och ner och med samma frekveThis thesis adresses modeling of quantum cascade lasers using non-equilibrium Green’s functions. Focus lies on the quantitative modeling of the gain when the systems are exposed to strong laser fields, as under realistic opertional conditions. In the first part, an introduction to the general concepts is provided, together with a discussion on approximate analytic expressions. The second part cons
Synopsis In methanol solutions of Zeise's salt, the parent complex [PtCl3(C2H4)]- as well as its solvolysis product, trans-[PtCl2(C2H4)(MeOH)], exchange rapidly with free ethene. The olefin exchange process, which is largely entropy controlled, involves the substitution labile site trans to the coordinated ethene. Abstract Complex equilibria in methanol/chloroform/dichloromethane solutions c
BACKGROUND: Albuminuria in maintenance heart transplantation (HTx) is associated with poor renal response when switching to a calcineurin inhibitor (CNI)-lowered or free immunosuppressive regimen using everolimus (EVR), but the significance of albuminuria associated with EVR treatment after early CNI withdrawal in de novo HTx is unknown. METHODS: We tested if glomerular filtration rate (mGFR, meas
Previous research suggests that there is an inverted U-shape curve for energy intensity in the long-run for Western Europewith a peak in the early 20th century. This paper tests the hypothesis that the increase of German and British energy intensity was an effect from the concentration of heavy industrial production to these countries, although the consumption of a significant share of these goods
I denna rapport har balkonginfästningar för en fastighet på Bo01-området i Malmö studerats. Fastigheten som heter Vitruvius innehåller fyra byggnader där två av dem har utkragande balkonger med intermittent infästning. Intermittent infästning innebär att den 50 mm köldbryggebrytande isoleringen som balkongerna är utrustade med, bryts regelbundet av en 300 mm betongklack. Armeringsjärnet som spänneIn this report the balconies’ abutments for a property in Bo01-area in Malmö has been studied. The property which is called Vitruvius contains four build-ings where two of them have corbelling balconies with intermittent abutments. With intermittent abutment means that the 50 mm thermal bridge insulation that the balconies is equipped with, is broken regularly by a 300 mm concrete heel. The reinfo
In the following report, a fire safety evaluation of Hotel Nissastigen in central Gislaved is presented. The building itself consists of five floors, whereof two are cellar and attic. Beyond the usual hotel business, Nissastigen both offers a place to eat at their restaurant and room for conferences, as well as acting as a gathering point for tourists, thus making it vital for the local economy.
Due to the rise of support for Populist Radical Right parties in nations around Europe during the past two decades, the circumstances which allow these new parties to emerge have been recurrently highlighted in academic research, and the ensuing debate has long been dominated by competing theories on when, how and why these changes occur. By shifting focus from the nations in which these new parti
Background: The thorough assessment of familial prostate cancer (PCa) risk is as important as ever to provide a basis for clinical counselling and screening recommendations. Objective: Our aim was to determine the age-specific risks of PCa and the risk of death from PCa according to the number and the age of affected first-degree relatives. Design, setting, and participants: The nationwide Swedish
