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Design of Foundations for Wind Turbines

The Swedish government has specified a goal for the Swedish wind power that in 2020 it will generate 30 TWh of energy per year. This should be compared with the present energy produced from wind power of 2.5 TWh / year. To meet these goals, several thousand new wind turbines have to be built. Today, we build the most land-based wind turbines on strong and stiff soils, but probably in the future

Framtiden för alternativa bränslen. Marknadspotentialen för flytande metan inom lastbilsmarknaden

Problem definition Since 1995, the vehicle-gas market has been growing at a rapid pace. One segment that has not kept up with this development is the heavy gas-powered trucks. One explanation is that the existing gas-powered trucks cannot compete against the traditional diesel trucks. Some examples of attributes that makes the gas alternative less attractive are engine power, efficiency, driving d

Surgical Care in Liberia and Implications for Capacity Building

BACKGROUND: Situational needs of health care facilities inform the optimal allocation of resources and quality improvement efforts. This study examines surgical care delivery metrics at a tertiary care institution in Liberia. METHODS: We retrospectively reviewed operative and ward logbooks from January 1 to December 31, 2012. Data parameters included patients' age, diagnosis, procedure, mortality,

Geriatric rehabilitation as an integral part of geriatric medicine in the Nordic countries

Objectives: First, to outline the theoretical and practical framework for geriatric rehabilitation in the Nordic countries and second, to survey the scientific medical publications for evidence-based geriatric rehabilitation. Methods: Brainstorming on geriatric rehabilitation in a working group of Nordic teachers in geriatric medicine. Papers on scientific programmes for geriatric rehabilitation f

Lateral stabilisation in multi-storey timber volume element buildings

Det ökade användandet av träbaserade volymelement i flerfamiljshus kräver effektiva och detaljerade beräkningsmetoder. Numeriska modeller av volymelementen ger stora fördelar med avseende på analys av stabilitet mot vindlaster genom möjligheten att beakta hela den tredimensionella konstruktionens styvhet.The use of timber volume elements (TVEs) in residential multi-storey buildings is increasing in popularity. Manufacturing methods and building processes have been streamlined to improve product quality. However, further streamlining still remains concerning the efficiency of current calculation methods, as many developers still use simple hand calculations. The objective with this dissertation was

Dynamic glucose enhanced imaging using direct water saturation

PURPOSE: Dynamic glucose enhanced (DGE) MRI studies employ CEST or spin lock (CESL) to study glucose uptake. Currently, these methods are hampered by low effect size and sensitivity to motion. To overcome this, we propose to utilize exchange-based linewidth (LW) broadening of the direct water saturation (DS) curve of the water saturation spectrum (Z-spectrum) during and after glucose infusion (DS-

How are socioeconomic status, social support, and health history associated with unhealthy lifestyle behaviours in middle-aged adults? Results of the Swedish CArdioPulmonary bioImage Study (SCAPIS) COHORT

Background: Unhealthy lifestyle behaviours, including unhealthy alcohol consumption, physical inactivity, smoking, and nonadherence to dietary recommendations, are major contributors to non-communicable diseases and mortality. While adopting healthy behaviours can reduce these risks in middle-aged adults, research is limited. Therefore, the aim of this study was to assess the distribution of unhea

Analytical validation of a standardized scoring protocol for Ki67 immunohistochemistry on breast cancer excision whole sections: an international multicenter collaboration

Aims: The nuclear proliferation marker Ki67 assayed by immunohistochemistry has multiple potential uses in breast cancer, but an unacceptable level of interlaboratory variability has hampered its clinical utility. The International Ki67 in Breast Cancer Working Group has undertaken a systematic programme to determine whether Ki67 measurement can be analytically validated and standardised among lab

Focal neocortical lesions impair distant neuronal information processing

Key points: Parts of the fields of neuroscience and neurology consider the neocortex to be a functionally parcelled structure. Viewed through such a conceptual filter, there are multiple clinical observations after localized stroke lesions that seem paradoxical. We tested the effect that localized stroke-like lesions have on neuronal information processing in a part of the neocortex that is distan

Four decades of satellite observations reveal climate-driven shifts and spatial heterogeneity in shallow lake Chlorophyll-a dynamics

Shallow lakes worldwide face escalating pressures from eutrophication and climate change, yet comprehensive monitoring of Chlorophyll-a (Chl-a) spatiotemporal dynamics remains challenging due to the high costs and logistical constraints of traditional sampling approaches across large, heterogeneous water bodies. Lake Balaton, a large shallow lake system (80 km long, 7 km wide, 3.7 m mean depth) in

Devices for Neonatal Peripheral Catheterization and Tip Confirmation : A Systematic Review and Meta-Analysis

Abstract – Introduction: Peripheral intravenous catheterization is commonly required in sick neonates but remains challenging due to small vessels, leading to multiple attempts and complications. This review evaluated the benefits and harms of device-assisted techniques versus standard technique. Methods: We searched MEDLINE, Embase, CENTRAL, Cochrane Reviews, WHO ICTRP, and ClinicalTrials.gov (Oc

Integrating Tumor-Intrinsic and Immunologic Factors to Identify Immunogenic Breast Cancers from a Low-Risk Cohort : Results from the Randomized SweBCG91RT Trial

PURPOSE: The local immune infiltrate's influence on tumor progression may be closely linked to tumor-intrinsic factors. The study aimed to investigate whether integrating immunologic and tumor-intrinsic factors can identify patients from a low-risk cohort who may be candidates for radiotherapy (RT) de-escalation.EXPERIMENTAL DESIGN: The SweBCG91RT trial included 1,178 patients with stage I to IIA

Mortality from gastrointestinal congenital anomalies at 264 hospitals in 74 low-income, middle-income, and high-income countries : a multicentre, international, prospective cohort study

Background: Congenital anomalies are the fifth leading cause of mortality in children younger than 5 years globally. Many gastrointestinal congenital anomalies are fatal without timely access to neonatal surgical care, but few studies have been done on these conditions in low-income and middle-income countries (LMICs). We compared outcomes of the seven most common gastrointestinal congenital anoma

Expiratory and inspiratory resistance and reactance from respiratory oscillometry defining expiratory flow limitation in obstructive lung diseases

Background: Expiratory flow limitation (EFL) during tidal breathing and lung hyperinflation have been identified as major decisive factors for disease status, prognosis and response to therapy in obstructive lung diseases. Aim: To investigate the delta values between expiratory and inspiratory resistance and reactance, measured using respiratory oscillometry and its correlation with air trapping a

Roadside PM2.5 concentrations measured with low-cost sensors and student science in Arba Minch, Ethiopia

Exposure to PM2.5 poses one of the biggest health threats, with traffic and biomass burning as dominant sources in urban areas of low-income countries. In Ethiopia, the combination of these two sources suggests a high roadside exposure. Because of a lack of resources for data collection, only few studies were conducted on roadside exposure in Ethiopia. Using low-cost sensors and student science co

Effects of N-3 Polyunsaturated Fatty Acids on Left Ventricular Function and Coronary Flow in Children with Type 1 Diabetes Mellitus

rposes: Dietary supplementation with N-3 Polyunsaturated Fatty Acids (n-3 PUFAs) could have beneficial effects on cardiovascular system in patients with type 1 diabetes mellitus (DM1). Methods: In a double-blind placebo controlled crossover study, 33 children with DM1 duration of more than one year were randomly and equally assigned to either n-3 PUFAs (2 gm/day, Nycoplus® Omega-3, 1000 mg) or plaPurposes: Dietary supplementation with N-3 Polyunsaturated Fatty Acids (n-3 PUFAs) could have beneficial effects on cardiovascular system in patients with type 1 diabetes mellitus (DM1). Methods: In a double-blind placebo controlled crossover study, 33 children with DM1 duration of more than one year were randomly and equally assigned to either n-3 PUFAs (2 gm/day, Nycoplus® Omega-3, 1000 mg) or

Multicentre, national, investigator-initiated, randomised, parallel-group, register-based superiority trial to compare extended ECG monitoring versus standard ECG monitoring in elderly patients with ischaemic stroke or transient ischaemic attack and the effect on stroke, death and intracerebral bleeding : the AF SPICE protocol

Introduction Atrial fibrillation (AF) is a major risk factor for ischaemic stroke and transient ischaemic attack (TIA), and AF detection can be challenged by asymptomatic and paroxysmal presentation. Long-term ECG monitoring after ischaemic stroke or TIA is recommended by all major societies in cardiology and cerebrovascular medicine as a secondary prophylactic measure. However, data on stroke red

Compliance with National and International Guidelines in the Treatment of Nonmotor Symptoms in Late-Stage Parkinson's Disease

Background. National as well as international Parkinson's disease (PD) treatment guidelines are available to guide clinicians. Previous research has shown that nonmotor symptoms (NMS) are pronounced in late-stage PD and has suggested that current treatment is insufficient and could be improved. Objectives. The aim of this study was to investigate to which degree the national and international trea

Short, medium, and long deferral of umbilical cord clamping compared with umbilical cord milking and immediate clamping at preterm birth : a systematic review and network meta-analysis with individual participant data

Background: Deferred (also known as delayed) cord clamping can improve survival of infants born preterm (before 37 weeks of gestation), but the optimal duration of deferral remains unclear. We conducted a systematic review and individual participant data network meta-analysis with the aim of comparing the effectiveness of umbilical cord clamping strategies with different timings of clamping or wit

Expected features of the course leader in the rehabilitation healthcare professionals’ higher education : A qualitative study on students’ perspectives

Course leaders in rehabilitation healthcare professionals’ higher education face challenges stemming from multi-disciplinarity and the co-existence of different stakeholders. So far, the literature mainly attributed to course leaders’ managerial tasks, neglecting other fundamental transversal skills. Students represent an essential source of information for understanding the expected characteristi