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We have evaluated the efficiency of two popular end-point methods to calculate ligand-binding free energies, LIE (linear interaction energy) and MM/GBSA (molecular mechanics with generalized Born surface-area solvation), i.e. the computational effort needed to obtain estimates of a similar precision. As a test case, we use the binding of seven biotin analogues to avidin. The energy terms used by M
In a controlled prospective randomized study the regimen doxorubicin (A) 40 mg/m2 + melphalan (M) 0.4 mg/kg was compared with A + M + cisplatin (C) 50 mg/m2 given every four weeks in advanced ovarian cancer, FIGO stage III or IV and with serous or anaplastic histology. From 1981 to 1983, 300 patients entered the study and 295 patients were evaluable for response, toxicity and long-term survival. A
BACKGROUND: Performance status (PS) is known as one of the strongest prognostic factors for survival in metastatic colorectal cancer patients. The aim of the present study was to analyze factors associated with poor PS assessed after resection for colorectal liver metastases and the impact on survival.METHODS: All patients undergoing curative resection for colorectal liver metastases between 2010
In rodent models of Parkinson disease in which transplants of dissociated rodent and human embryonic mesencephalic tissue, rich in dopamine neurons, have been studied, only 5-20% of the dopamine neurons survive the implantation procedure. We have investigated the effects of inhibiting free radical generation with two lazaroids, U-74389G and U-83836E, on the survival of embryonic rat dopamine neuro
Cystatin C, a 13 kDa-protein, is produced by most nucleated cells and is catabolized by the renal tubular cells after passing the glomerular filter. It belongs to the family 2 of the cystatin superfamily of proteins. The function of cystatin C is to regulate the activity of cysteine proteinases and cystatin C seems to be the main cysteine proteinase inhibitor of most investigated human biological
Increasingly, buildings are becoming complex “systems of systems” with many materials and attributes combining to create a whole that aims to meet a variety of design objectives including but not limited to functionality, aesthetic appeal, sustainability, safety, and security. We are now seeing this complexity move from commercial buildings and iconic structures to encompass even the residential s
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Postadress: Humanekologiska avdelningen, Sölvegatan 12, 223 62 Lund
Besöksadress och undervisning: Geocentrum I, Sölvegatan 10, Lund
https://www.keg.lu.se/sites/keg.lu.se/files/heka22_1_schema_vt_2017.pdf - 2026-07-08
Microsoft Word - CB 261217 LUCC-C symposium program 2026 LUCC-Child mini-symposium 2026 “CHILDHOOD CANCER CARE AND RESEARCH – PAST, PRESENT AND FUTURE” Dear all, we are pleased to invite you to a physical LUCC-Child mini-symposium, on Wednesday 25th of February 2026, from 13.30 to 18:30, followed by guided tour and dinner. We will meet at Skissernas Museum in central Lund, where we will also have
Prediction of the development of islet autoantibodies through integration of environmental, genetic, and metabolic markers OR I G I N A L AR T I C L E Prediction of the development of islet autoantibodies through integration of environmental, genetic, and metabolic markers Bobbie-Jo M. Webb-Robertson1,2 | Lisa M. Bramer3 | Bryan A. Stanfill3 | Sarah M. Reehl3 | Ernesto S. Nakayasu1 | Thomas O. Met
https://www.teddy.lu.se/sites/teddy.lu.se/files/2021-06/121_MP193_Webb-Robertson_JDiabetes_2020%20(2).pdf - 2026-07-08
https://www.soc.lu.se/britt-marie-johansson - 2026-07-08
https://www.lub.lu.se/internt/christel-holmberg - 2026-07-08
Press Release: Raoul Wallenberg Institute Launches Somalia Programme Inception Phase to Strengthen National Human Rights System - The Raoul Wallenberg Institute of Human Rights and Humanitarian Law Skip to content Search for: Search Button Home About Us Who We Are Our History About Raoul Wallenberg Our Theory of Change Staff Opportunities Annual Reports Whistleblower Our work What we do Multi-Disc
24 to 27 April 2025 The collaboration between INTONAL and IAC is renewed this year, once again hosting IAC’s Acousmonium in the Red Room. First set up fifteen years ago, this unique sound system, now comprising more than 40 speakers, has been continuously refined and improved year after year thanks to the artists who have used it, experimented with it, and proposed innovations to expand its possib
https://www.iac.lu.se/intonal/intonal-2025-acousmatic-concerts-iac - 2026-07-07
https://www.cors.lu.se/learning-collaboration - 2026-07-07
Major problems are related to how we build our societies, how we allocate our resources, how we consume and how we travel. But what does an ecologically and socially sustainable world look like? These are questions that engage many social scientists. It is now well known that our way of life is not environmentally sustainable. We need to create sustainable consumption patterns and a circular econo
https://www.sam.lu.se/en/research/sustainable-societies - 2026-07-07
Resourcification THEME 2019-2020 In a world of nearly 10 billion people, competition for the conditions of life and wealth can only accelerate. Our contention is that with such increasing competition, people and organizations will turn an increasing amount of material as well as immaterial things into resources – a process that we label resourcification. This will have major consequences for socia
https://www.pi.lu.se/en/sites/pi.lu.se.en/files/2021-01/resourcification_en.pdf - 2026-07-08
