Sökresultat

Popular Abstract in Swedish I detta avhandlingsarbete studerades mekanismer underliggande utveckling av multipel organdysfunktion (MODS), med fokusering på intercellulär proinflammatorisk reglering och adhesionmolekylers roll vid den fortsatta utvecklingen av organskada samt att studera eventuella organspecifika skillnader. Målsättningen var att finna nya behandlingar och prevention mot utvecklingIntestinal I/R is considered to be an important initiating event in several pathophysiological conditions such as trauma, bleeding, sepsis and pancreatitis, frequently leading to concomitant both single and potentially multiple organ dysfunction. The purpose of this thesis was to study mechanims underlying the development of multiple organ dysfunction, with special focus on intercellular proinflam

Due to the recent advances in digital detector technology, there is an increasing trend in the use of digital mammography (DM) as a concurrent modality with screen-film mammography (SFM). In order to fully realize its potential, the components of a DM system should be optimized with respect to clinical image quality in order for clinicians to make accurate diagnoses. The studies in this work invol

OBJECTIVE: Increased inflammation and oxidative stress have been shown in Major Depressive Disorder (MDD), although there is significant heterogeneity across studies. Whether markers of inflammation and oxidative stress are associated with antidepressant treatment response in MDD is currently unclear. The goals of the present study are to investigate markers of inflammation and oxidative stress in

Background: Galectin 3 and ST2 are mediators and biomarkers of myocardial fibrosis and remodeling that have recently entered the clinical practice guidelines as prognostic factors in heart failure patients. Elevated galectin 3 and ST2 levels in acute myocardial infarction patients have also been associated with increased incidence of adverse events during follow-up. Purpose: We aimed to assess the

Uppsatsen fokuserar på privat skadeståndstalan vid konkurrensrättsliga överträdelser och på det nya direktivet 2014/104/EU, om vissa regler som styr skadeståndstalan enligt nationell rätt avseende överträdelser av medlemsstaternas och Europeiska unionens konkurrensrättsliga bestämmelser. Enligt unionsrätten har alla enskilda aktörer rätt till ersättning för skada som uppkommit till följd av en öveThe main focus of this thesis are private actions for damages due to infringements of the antitrust rules and the new directive 2014/104/EU, on certain rules governing actions for damages under national law for infringements of the competition law provisions of the Member States and of the European Union. According to European union law, all private actors are entitled to compensation for damages

I denna rapport redovisas populationstrender för 228 svenska fågelarter för olika långa tidsperioder. Vi visar också korttidstrender för 12 arter av större däggdjur. Fåglarna har räknats höst, vinter, vår och sommar enligt strikt standardiserade metoder. Sommar- respektive vinterpunktrutter har räknats sedan 1975, i huvudsak i södra Sverige. Standardrutterna räknas också på sommaren (sedan1996) meWe present the results of the Swedish Bird Survey, run by the Department of Biology, Lund University, as a part of the National Monitoring Programme of the Swedish Environmental Protection Agency. The results for 2020 include data from: 564 winter point counts in 2019/2020 (45th winter), of which 274 were carried out during the Christmas/New Year count, 210 summer point count routes (46th year) an

Background: Metabolic complications with obesity are frequent in childhood acute lymphoblastic leukemia (ALL) survivors treated with cranial radiotherapy (CRT). Childhood onset Craniopharyngioma (CP) survivors without hypothalamic (HT) involvement are spared gross obesity. Magnetic resonance diffusion tensor imaging (DTI) provides information of microstructure function of the brain and quantified

Objective: To determine whether repeated [18F]fluorodeoxyglucose-positron emission tomography/computed tomography (FDG-PET-CT) scans can predict increased cancer-specific survival (CSS) after induction chemotherapy followed by radical cystectomy (RC). Patients and Methods: Between 2007 and 2018, 86 patients with clinically lymph node (LN)-positive bladder cancer (T1–T4, N1–N3, M0–M1a) were include

Tillgång och Effektfrågan – Biogasens Roll i det Gröna Norrbotten Allt fler nyfikna ögon riktas mot Norrland i takt med att den nordligaste landsänden ångar på framåt i utvecklingen mot fossilfria industrier; kommande år planeras miljardinvesteringar i fossilfria tekniker i region Norrbotten, en satsning som kallas den gröna omställningen. Men för att kunna förse etableringarna och samhället medGreat investments are planned in the north of Sweden the coming years, not the least in the county of Norrbotten where the projects collectively are referred to as the green transition due to the focus on fossil-free techniques. But to be able to secure a sustainable energy supply and reach the goal set by the member states of the European Union of a carbon dioxide neutral union in 2050 the produc

In forensics, identifying and comparing DNA is common practice. One way to analyse DNA is through high-resolution DNA melting. When melting DNA experimentally, the rate of a given sequence of DNA denaturing from its double-helix form into two separate strands is measured as a function of temperature. In this thesis, the application of high-resolution DNA melting analysis to distinguish individual

We present a method to produce small pitch gratings for X-ray interferometric imaging applications, allowing the phase sensitivity to be increased and/or the length of the laboratory setup to be minimized. The method is based on fabrication of high aspect ratio silicon microstructures using deep reactive ion etching (Bosch technique) of dense grating arrays and followed by conformal electroplating

Under certain conditions, secondary organic aerosol (SOA) particles can exist in the atmosphere in an amorphous solid or semi-solid state. To determine their relevance to processes such as ice nucleation or chemistry occurring within particles requires knowledge of the temperature and relative humidity (RH) range for SOA to exist in these states. In the Cosmics Leaving Outdoor Droplets (CLOUD) exp

Immunosensors made with nanostructured films are promising for detecting cancer biomarkers, even at early stages of the disease, but this requires control of film architecture to preserve the biological activity of immobilized antibodies. In this study, we used electrochemical impedance spectroscopy (EIS) to detect Prostate Specific Antigen (PSA) with immunosensors produced with layer-by-layer (L

Lactic acid bacteria with antifungal properties can be used to control spoilage of food and feed. Previously, most of the identified metabolites have been isolated from cell-free fermentate of lactic acid bacteria with methods suboptimal for detecting possible contribution from volatiles to the antifungal activity. The role of volatile compounds in the antifungal activity of Lactobacillus paracase

Building on insights from ecological economics and philosophy of technology, this book offers a novel, interdisciplinary approach to understand the contradictory nature of Solar photovoltaic (PV) technology.Solar photovoltaic (PV) technology is rapidly emerging as a cost-effective option in the world economy. However, reports about miserable working conditions, environmentally deleterious mineral

Real-time applications introduce new requirements on wireless networks and impose quality thresholds on parameters like delay, jitter, throughput, and packet loss in order to run smoothly. This paper addresses this issue by presenting a MAC scheme that offers real-time applications the opportunity to reserve transmission time based on their QoS requirements for contention-free medium access. Our s

Variants in the TCF7L2 gene (transcription factor 7-like 2) have shown strong association with type 2 diabetes with two defined risk haplotypes, HapA and HapB(T2D). TCF7L2 may play a role in both glucose homeostasis and adipogenesis. Our aim was to characterize the TCF7L2 mRNA expression and regulation in human adipose tissue. We quantified TCF7L2 mRNA levels in cultured human adipocytes and in bi

Purpose. To assess rehabilitation, type of follow-up visits and outcome after bipolar hemiarthroplasty for femoral neck fracture. Method. Two hundred thirty-six consecutive patients with femoral neck fractures treated with hemiarthroplasty were followed for 30 months. Results. One hundred sixty-eight (71%) were women, 175 (74%) over 80 years old and 53 (22%) were demented. Of 150 patients with ava

The electronic structure of as-grown and high temperature (1625 C) annealed chemical vapour deposition boron-doped (1-4 ppm) diamond films has been studied using a scanning photoelectron microscope with lateral resolution in the 1 mum range. The fresh surfaces have been obtained by cleaving free-standing films in situ at a pressure of 7 X 10(-11) Torr. The major part of the contrast in photoelectr