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Gene and Protein Profiling of the Preeclamptic Placenta

Aims State-of-the-art methodology was used to screen and profile the placenta, gene and protein expression, for changes related to preeclampsia (PE) and cases with increased resistance in the uterine arteries. Women with increased resistance in the uterine arteries have increased risk of developing PE. Since not all of them develop PE, this group, identified by Doppler ultrasound, was included to

White Matter Brain Development after Exposure to Circulating Cell-Free Hemoglobin and Hyperoxia in a Rat Pup Model

Neonates born with critical congenital heart defects are at risk of diffuse white matter injuries and neurodevelopmental impairments. This study aimed to determine the impact of circulating cell-free hemoglobin and hyperoxia, both present during cardiopulmonary bypass circulation, on white matter brain development. Postnatal day 6 rat pups were injected intraperitoneally with cell-free Hb or vehic

Are growth forms consistent predictors of leaf litter quality and decomposability across peatlands along a latitudinal gradient?

Plant growth forms are widely used to predict the effects of environmental changes, such as climate warming and increased nitrogen deposition, on plant communities, and the consequences of species shifts for carbon and nutrient cycling. We investigated whether the relationship between growth forms and patterns in litter quality and decomposition are independent of environmental conditions and whet

Metabolic and Lifestyle related risk factors for pancreatic cancer

Background and aims: In spite of the fact that pancreatic cancer is a relatively infrequent disease, it ranks 8th in the worldwide ranking of cancer death due to the poor prognosis. The mortality rate is almost as high as the incidence with a M/I ratio of 98%, indicating an extremely dismal clinical course. This makes it imperative to try to develop new therapeutic strategies and to try to identif

Inverse method using boosted regression tree and k-nearest neighbor to quantify effects of point and non-point source nitrate pollution in groundwater

Nitrate pollution of groundwater has increased dramatically worldwide due to increase of population and agricultural productivity. The resulting nitrate concentration in groundwater is usually a combination of various types of point and non-point pollutant sources. It is often difficult to distinguish between these sources since groundwater is formed in large and complex catchments with various na

Does the Swedish specialized health care respond to competition inducing reforms? -Effects of the Freedom of Choice Act on quality, volume, efficiency and upcoding for elective patients.

This study aims to analyze the effects of competition on quality, efficiency, produced volume and gaming the system of specialized health care in Sweden, after implementation of the Freedom of Choice Act (LOV, Lagen om Vårdval). This is done by using data for specialized ophthalmology, which is a patient-elective diagnostic category. The motive behind the law, which established free entry for priv

Torkningens inverkan på pappers krypegenskaper

A low creep rate and a long lifetime are important mechanical properties for corrugated board and its constituent’s linerboard and fluting. These properties ensure that the package protects the goods during the entire duration of transport and storage. This study involves several creep and tensile tests of linerboard in the machine direction (MD). The objective is to investigate how free or rest

Electric multipole moment fluctuations in polar liquids.

A general expression for the distribution of the fluctuating 2(l)-pole moment M(l) of a spherical sample of dielectric material is derived on the basis of dielectric theory combined with statistical mechanics. The formulas are compared with results from computer simulations of a weakly coupled Stockmayer fluid and the agreement is shown to be excellent. Furthermore, we calculate the size of the co

Microcalorimetry

The isothermal titration calorimetry (ITC) provides the most direct method to measure the internal energy of the confined viral genome. In order to experimentally dissect the thermodynamic determinants of viral DNA packaging and ejection energetics, we were first to use ITC to directly measure the heat released by DNA ejection from a virus capsid. This approach allows one to address experimentally

https://www.virus-biophysics.lu.se/methods-and-techniques/microcalorimetry - 2026-04-29

Heme-induced contractile dysfunction in Human cardiomyocytes caused by oxidant damage to thick filament proteins.

Intracellular free heme predisposes to oxidant-mediated tissue damage. We hypothesized that free heme causes alterations in myocardial contractility via disturbed structure and/or regulation of the contractile proteins. Isometric force production and its Ca(2+)-sensitivity (pCa50) were monitored in permeabilized human ventricular cardiomyocytes. Heme exposure altered cardiomyocyte morphology and e

Ultraweak light emission, free radicals, chilling and light sensitivity

Ultraweak light emission (UWLE) was measured from leaves of various chillingsensitive (Lycopersicon esculentum, Cucumis sativus and Phaseolus vulgaris) and tolerant (Pisum sativum and Vicia faba) plants after exposure to low (47C) temperature in the light. UWLE increased upon chilling treatment combined with illumination with 200 mol m2 s1 PAR in all plants, by about 30 in tolerant and by more tha

Urbel evelin

Microsoft Word - freight transport and the environment-final.doc Lund University International Master’s Programme in Environmental Science Freight Transport and the Environment. Environmental Impact of Increased Transportation due to Product Price Differences Master’s Thesis Prepared by Evelin Urbel Address: Kuldnoka 15-113, 10619 Tallinn Estonia Telephone: +372 656 44 23 Mobile: +372 56 478 858 E

https://www.lumes.lu.se/sites/lumes.lu.se/files/urbel_evelin.pdf - 2026-04-30

Kontraherad autonomi? - En komparativ studie mellan Marshallöarnas fria association och Grönlands självstyrereglering samt analys av en grönländsk fri association

Folkens och nationernas självbestämmande är en internationell rättslig princip som sträcker sig långt tillbaka i historien. Under perioden efter andra världskriget blev principen central i hanteringen av tidigare koloniala territorier. Ett sätt för ett område att uppnå självständighet, men under de förutsättningar som området själv kräver, blev den fria associationen. Ett sådant associationsförhålThe right of all peoples’ and nations’ self-determination is an international legal principle that dates far back in history. During the period following the Second World War, it became central to the treatment of former colonial territories. One way for a territory to become independent, but under the prerequisites itself requires, became the free association. A free association relationship is c

A framework for business continuity management in a multiactor context

Business continuity management (BCM) is an analytic process capable of fostering the resilience of critical societal functions. While previous research on BCM primarily has focused on its applications within individual organizations, today's modern society involves networks of interdependent actors collectively delivering these essential functions to end users. This necessitates an expansion of BC

Combining information from range use and habitat selection: sex-specific spatial responses to habitat fragmentation in tawny owls Strix aluco

How individuals respond to habitat heterogeneity is usually measured as variation in range size and by ranking the relative importance of habitat types (habitat selection). The combined effect of how individuals incorporate different habitat types in their home ranges and allocate their time budget between them is rarely derived. Additionally, when home range size varies between individuals, habit

Phage display and kinetic selection of antibodies that specifically inhibit amyloid self-replication

The aggregation of the amyloid β peptide (Aβ) into amyloid fibrils is a defining characteristic of Alzheimer's disease. Because of the complexity of this aggregation process, effective therapeutic inhibitors will need to target the specific microscopic steps that lead to the production of neurotoxic species. We introduce a strategy for generating fibril-specific antibodies that selectively suppres

A Screening Tool to Quickly Identify Movement Disorders in Patients with Inborn Errors of Metabolism

BACKGROUND: Movement disorders are frequent in patients with inborn errors of metabolism (IEMs) but poorly recognized, particularly by nonmovement disorder specialists. We propose an easy-to-use clinical screening tool to help recognize movement disorders.OBJECTIVE: The aim is to develop a user-friendly rapid screening tool for nonmovement disorder specialists to detect moderate and severe movemen

Dynamics of socioeconomic-related health inequalities in Australia

Socioeconomic-related inequalities in health despite gains in extended life spans remain a key equity issue that calls into question society’s burden of illness and the role of a universal healthcare system. The extent to which socioeconomic conditions systematically vary with population health has been a matter of empirical analysis aimed at measuring social equity. This paper attempts to measure

Analysing Self-Preferencing in EU Competition Law - Understanding the Similarities and Differences Between Article 102 TFEU and the Digital Markets Act

Article 102 TFEU has long been the legal framework for addressing dominant undertakings abusing their position. In the new digital era, these undertakings have been found to favour themselves through self-preferencing. Therefore, the European Commission proposed the Digital Markets Act to address the structural problems that Article 102 TFEU could not. The DMA targets gatekeepers, who often hold d