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Normalization of haemoglobin concentration with recombinant erythropoietin has minimal effect on blood haemostasis

BACKGROUND: Elevation of haemoglobin (Hb) with recombinant erythropoietin (rHuEpo) in patients with chronic renal failure has raised concern of increased risk of thromboembolic diseases. In this study, a substudy of the Scandinavian multicentre trial, we examined the influence on haemostatic parameters of normalization of Hb levels from subnormal levels in patients with chronic renal failure.METHO

Platform For Strategic Work 2026–2027

Platform for Strategic Work | Lund University 2026–2027 Platform for Strategic Work LUND UNIVERSITY | 2026–2027 PLATFORM FOR STRATEGIC WORK | 2026–2027 2 Greater international impact, building upon strong local and regional engagement PLATFORM FOR STRATEGIC WORK 2026–2027 The world around us is significantly more unpredict­ able and changeable than before and the conditions are more complex. The f

https://www.staff.lu.se/sites/staff.lu.se/files/2026-04/Platform%20for%20Strategic%20Work%202026%E2%80%932027.pdf - 2026-05-06

Value of Intact Prostate Specific Antigen and Human Kallikrein 2 in the 4 Kallikrein Predictive Model : An Individual Patient Data Meta-Analysis

Purpose: The 4 kallikrein panel, commercially available as the 4Kscore®, is a statistical model that has been shown to accurately predict Gleason Grade Group 2 or greater (high grade) cancer on biopsy and the long-term risk of distant prostate cancer metastases. The panel includes 2 novel markers, namely intact prostate specific antigen and hK2. It has been questioned whether these 2 additional ma

The evolution of epilepsy surgery in tuberous sclerosis in Sweden: A national registry study

PurposeThis study aimed to characterize the Swedish cohort of surgically treated patients with TSC and explore differences in preoperative investigation and outcome over time.MethodsData on patient and seizure characteristics were retrieved from the Swedish National Epilepsy Surgery Register. Two-year follow-up results were compared between the years 1997–2010 and 2011–2018. Preoperative investiga

Ministry of imagination

Memories of the transition Memories of the transition is fictive. However, it is knowledge-based speculation. Much of the story is inspired by existing proposals, emerging innovations, or research on the transformations needed to meet our climate targets. We have collected some of these imaginative seeds below so that you can understand and construct your own vision of a post-fossil society. Conte

https://www.climatefutures.lu.se/ministryofimagination - 2026-05-05

A matrix-free algorithm for multiple wavelength fluorescence tomography

In the recent years, there has been an increase in applications of non-contact diffusion optical tomography. Especially when the objective is the recovery of fluorescence targets. The non-contact acquisition systems with the use of a CCD-camera produce much denser sampled boundary data sets than fibre-based systems. When model-based reconstruction methods are used, that rely on the inversion of a

High Precision Mean Field Results for Lattice Gauge Theories : with special attention paid to the gauge dependence of mean-field perturbation theory to finite order

We do mean-field perturbation theory for U(1) lattice gauge theory in the axial gauge, and evaluate corrections from fluctuations up to fourth order for the free energy and plaquette energy. Comparing with similar results previously obtained in the Feynman gauge we find, to those orders studied, a gauge dependence of the size of the first correction term neglected with one exception. This gauge de

Label-free enrichment of avian Leucocytozoon using flow cytometric sorting

The group of haemosporidian parasites is of general interest to basic and applied science, since several species infect mammals, leading to malaria and associated disease symptoms. Although the great majority of haemosporidian parasites appear in bird hosts, as in the case of Leucocytozoon buteonis, there is little genomic information about genetic aspects of their co-evolution with hosts. Consequ

Preservation of potassium balance is strongly associated with insect cold tolerance in the field: a seasonal study of Drosophila subobscura

There is interest in pinpointing genes and physiological mechanisms explaining intra- and interspecific variations in cold tolerance, because thermal tolerance phenotypes strongly impact the distribution and abundance of wild animals. Laboratory studies have highlighted that the capacity to preserve water and ion homeostasis is linked to low temperature survival in insects. It remains unknown, how

Precise transit and radial-velocity characterization of a resonant pair : The warm Jupiter TOI-216c and eccentric warm Neptune TOI-216b

TOI-216 hosts a pair of warm, large exoplanets discovered by the TESS mission. These planets were found to be in or near the 2:1 resonance, and both of them exhibit transit timing variations (TTVs). Precise characterization of the planets’ masses and radii, orbital properties, and resonant behavior can test theories for the origins of planets orbiting close to their stars. Previous characterizatio

Hopes and fears : the case of Georgian asylum seekers in the EU

Since March 2017, when the EC allowed visa-free travel to the Schengen area for Georgian citizens, the member states warned about the sharp and continuous rise in the number of unfounded asylum seekers from Georgia. It became the subject of active discussion at the political level, as the visa-waiver deal with the EU is an important aspect of EU-Georgia relations. Even though the rising number of

Holding onto Electrons in Alkali Metal Halide Clusters: Decreasing Polarizability with Increasing Coordination

The connection between the electronic polarizability and the decrease of the system size from macroscopic solid to nanoscale clusters has been addressed in a combined experimental and model-calculation study. A beam of free neutral potassium chloride clusters has been probed using synchrotron-radiation-based photoelectron spectroscopy. The introduction of "effective" polarizability for chlorine, l

Monte Carlo simulation of defect-free cross-linked polyelectrolyte gels

Model systems of cross-linked polyelectrolyte gels were investigated by means of Monte Carlo simulations. The model contained a charged defect-free th ee-dimensional network of a diamond-like topology and explicit counterions. Pressure vs volume relations and chain extensions were determined and compared to those of the corresponding polyelectrolyte solution. The structure of the gel was character

Paradoxical decrease in cytosolic calcium with increasing depolarization by potassium in guinea-pig mesotubarium smooth muscle

The free intracellular Ca2+ concentration ([Ca2+]i) was measured simultaneously with isometric force in strips of guinea-pig mesotubarium using the Fura-2 technique. [Ca2+]i and force were maximal at a relatively low (30 mM) concentration of extracellular K+ ([K+]o), and declined at 90 and 140 mM K+. Plateau values of both [Ca2+]i and force were higher in the presence of 5.10(-6) M ryanodine, indi

Size of environmental grain and resource matching

For most animals their foraging environment consists of a patch network. In random environments there are no spatial autocorrelation at all, while in fine-grained systems positive autocorrelations flip to negative ones and back again against distance. With increasing grain size the turnover rate of spatial autocorrelation slows down. Using a cellular automaton with foragers having limited informat

Leukocytosis at the onset of diabetes in crosses of inbred BB rats

Inbred lymphopenic, diabetes-prone (DP) and non-lymphopenic, diabetes-resistant (DR) BB rats in a specific pathogen-free (SPF) colony were subjected to a cross-intercross breeding experiment which showed diabetes to segregate as a recessive trait. All DP rats, but none of the DR and F1 rats, developed diabetes. In contrast, about 25% of the F2 rats developed diabetes which made it possible to stud