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DNA compaction at hydrophobic surfaces induced by a cationic amphiphile

Cetyltrimethylammonium bromide (CTAB) induces partially irreversible compaction of DNA-adsorbed layers on hydrophobic silica. Additionally, there is a synergistic increase in the adsorbed amount when both CTAB and DNA are present as compared to the surface excess concentration of either of the individual components. In this study of the DNA adsorption and DNA-CTAB coadsorption by ellipsometry, emp

Essays on Social Capital, Health and Socioeconomic Inequalities in Health A Health Economic Study

The thesis comprises four independent research papers and a summary that focus on two related dimensions. The first dimension focuses on the understanding of the production of health. Particularly, the question is asked whether community's stock of social capital influence individual's health. The second dimension focuses on an attempt to understand the causes of socioeconomic health inequality (S

Present status and recent results from the APS SASE FEL

The Low-Energy Undulator Test Line (LEUTL) at the Advanced Photon Source, Argonne National Laboratory, is intended to demonstrate the basic operation of a SASE-based free-electron laser. Goals include comparison of experimental results With theoretical predictions and scaling laws, identification of problems relevant to fourth-generation light source construction and operation and the means of add

Intraoperative collection of shed blood with citrated compresses for autotransfusion. An experimental study in pigs

Six pigs were used to study whether the collection of shed blood by means of surgical compresses instead of suction traumatizes such blood. In an in vivo part of the study, the whole blood volume of the pigs was retransfused after treatment with citrated compresses, and in an in vitro part the blood was treated extensively with compresses and analyzed. All animals survived, with a minor fall in he

How to Apply

The National ATMP Research School offers an ongoing application process, providing multiple opportunities throughout the year for talented individuals to join our program. With different application pathways, applicants can pursue opportunities aligned with their research interests and career goals. We offer three different types of students the opportunity to join our program: co-funded PhD stude

https://www.stemcellcenter.lu.se/atmp-research-school/apply - 2026-05-07

Reglerna om ansvarsfrihet vid rättelse av oriktig uppgift på eget initiativ

Då oriktig uppgift lämnats till ledning för beskattning kan den uppgiftsskyldige riskera skattetillägg eller, i de svårare fallen, bli ansvarig för skattebrott. Ett skattetillägg utgår som huvudregel med ett pålägg om 40 % på den skatt som skulle ha erlagts och de vanliga straffrättsliga påföljderna, böter och fängelse, tillämpas vid skattebrott. Fängelsestraffet kan som högst bli sex år då oriktiIn cases where inaccurate information has been sent to tax authorities, the responsible person is risking surcharge or in worse cases making herself guilty of tax offence. A basic rule implies that a surcharge means an additional 40 % to the normal taxes and when it comes to cases of tax offence, the ordinary penalties of criminal law, fines and prison, are practiced. The highest prison sentence f

Mandating transparency on deforestation and ecosystem conversion

The production of eggs, meat, and dairy products in the EU indirectly contributes to deforestation and ecosystem conversion (DEC) in Latin America due to extensive imports of soy for animal feed. This thesis explores under which preconditions the mandatory European Sustainability Reporting Standards for the agriculture and farming sector can increase transparency in the opaque soy supply chains an

Labour Productivity in the Building Industry – Studies of Uganda

Research has been pointing out that productivity in the building industry is stagnant and in some cases declining. Poor productivity of craftsmen is one of the causes of cost and time overruns on building projects. Productivity of labour is particularly important especially in developing countries where most of the building work is still carried out on manual basis. The objective of this research

Dense downtown living more carbon intense due to higher consumption : A case study of Helsinki

Hindering urban sprawl is one of the main goals for contemporary urban planning. Urban density is considered crucial in climate change mitigation since it reduces automobile dependence and decreases unit sizes, for example. This letter analyzes the effect of density in a city context. In the study the Finnish capital Helsinki is divided into two areas of different urban densities: the high density

Heart rate and premature atrial contractions at 24hECG independently predict atrial fibrillation in a population-based study

BACKGROUND: Low resting heart rate and premature atrial contractions (PACs) predict incident atrial fibrillation (AF) and could be interdependent, since PACs occur in the gaps between normal beats.OBJECTIVE: To study the association between low heart rate at 24hECG, PACs and incident AF in a prospective population-based cohort.METHODS: In the Malmö Diet and Cancer study, 24hECGs were performed in

Dihydromyricetin and Salvianolic acid B inhibit alpha-synuclein aggregation and enhance chaperone-mediated autophagy

Background: Progressive accumulation of α-synuclein is a key step in the pathological development of Parkinson's disease. Impaired protein degradation and increased levels of α-synuclein may trigger a pathological aggregation in vitro and in vivo. The chaperone-mediated autophagy (CMA) pathway is involved in the intracellular degradation processes of α-synuclein. Dysfunction of the CMA pathway imp

Imatinib treatment of paediatric Philadelphia chromosome-positive acute lymphoblastic leukaemia (EsPhALL2010) : a prospective, intergroup, open-label, single-arm clinical trial

Background: The EsPhALL2004 randomised trial showed a 10% advantage in disease-free survival for short, discontinuous use of imatinib after induction compared with no use of imatinib in patients with Philadelphia chromosome-positive acute lymphoblastic leukaemia receiving Berlin-Frankfurt-Münster chemotherapy and haemopoietic stem-cell transplantation (HSCT). Other contemporary studies showed an a

A2030 monthly Update 250811

Agenda 2030 Graduate School monthly newsletter #7 2025-08-11 Ylva van Meeningen Hi! It is once again August and the Agenda 2030 Graduate School’s office is back in business. Time to brush of all you have put to the side for a later day and to try and figure out what it was you were working on before you went away. My big summer vacation project for one was a success! Going interrailing through Eur

https://www.agenda2030graduateschool.lu.se/sites/agenda2030graduateschool.lu.se/files/2025-08/A2030_monthly%20update_250811.pdf - 2026-05-08

Marknadseffektivitet och förtroende – Om transaktionskostnader vid publika förvärv och att upprätthålla allmänhetens förtroende för aktiemarknaden

En av mekanismerna som ökar välståndet i ett samhälle är att avtal kommer till stånd mellan rationella nyttomaximerande aktörer. När avtal sluts ökar parternas välstånd och välståndet i samhället då avtalsobjektet efter avtalet ägs av den part som värdesätter den högst. En sådan transaktion frigör kvasiränta vilket kvantifierar ökningen av välståndet i samhället. Transaktioner kan dock förhindras

Generation and Characterization of SARS-CoV-2 Neutralizing Nanobodies

Single-domain antibody fragments, also called nanobodies, that target the spike glycoprotein of SARS-CoV-2 can potently neutralize the virus and prevent infection. In our first aim, we investigated whether their neutralization potency can be further increased by multimerization and generated multivalent constructs of a recently identified SARS-CoV-2 neutralizing nanobody, Ty1. We applied a novel m

Influence of age and sex steroids on bone density and geometry in middle-aged and elderly European men

The influence of age and sex steroids on bone density and geometry of the radius was examined in two European Caucasian populations. Age-related change in bone density and geometry was observed. In older men, bioavailable oestradiol may play a role in the maintenance of cortical and trabecular bone mineral density (BMD). To examine the effect of age and sex steroids on bone density and geometry of

Coarse-Grained Models of Ionic Solutions

Popular Abstract in English Typically, when we speak of ionic solutions we mean a salt (as solute) dissolved in some liquid (the solvent). In this thesis, we predominantly consider ionic solutions for which there is no solvent---room-temperature ionic liquids (RTILs). It follows that these liquids have a large concentration of charged particles, a property that causes them to be effective electrRoom-temperature ionic liquids (RTILs) are compounds composed entirely of ions, which are liquid at temperatures below 100 degrees Celsius. Their high ionic strength and strong coupling make them useful for a number of applications, e.g. as electrolytes in supercapacitors. These properties also make them interesting subjects for theoretical research, as the canonical theories of the electrical dou

Upregulation of contractile endothelin type B receptors by lipid-soluble cigarette smoking particles in rat cerebral arteries via activation of MAPK

Cigarette smoke exposure increases the risk of stroke. However, the underlying molecular mechanisms are poorly understood. Endothelin system plays key roles in the pathogenesis of stroke. The present study was designed to examine if lipid-soluble (dimethyl sulfoxide-soluble) cigarette smoke particles (DSP) induces upregulation of contractile endothelin type B (ETB) receptors in rat cerebral arteri

Lipid deposition in Kupffer cells after parenteral fat nutrition in rats: a biochemical and ultrastructural study

OBJECTIVE: To study fat metabolism and evaluate lipid deposition in hepatocytes and Kupffer cells during parenteral nutrition (PN) with or without fat. DESIGN: 20 male Sprague-Dawley rats, divided into four groups, were investigated. Rats fed orally were used as a reference group and compared to three groups of rats receiving PN either without fat or with 33% of non-protein energy as fat or with 6

GPR40 protein levels are crucial to the regulation of stimulated hormone secretion in pancreatic islets. Lessons from spontaneous obesity-prone and non-obese type 2 diabetes in rats.

The role of islet GPR40 protein in the pathogenesis of diabetes is unclear. We explored the influence of GPR40 protein levels on hormone secretion in islets from two rat models of spontaneous type 2 diabetes displaying either hyperlipidaemia or hyperglycaemia. GPR40 expression was analysed by confocal microscopy, Western blot and qPCR in islets from preobese Zucker (fa/fa) rats, diabetic Goto-Kaki