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Molecular development of a thermostable β-glucosidase for modification of natural products

Popular Abstract in English The gene encoding a β-glucosidase originating from the extreme thermophile Thermotoga neopolitana has been cloned and expressed in Escherichia coli. The aim was to produce a thermostable enzyme that could be used to remove sugar residues from glucosylated natural products classified as flavonoids by applying a method combining extraction in hot pressurized water with enThe gene encoding a β-glucosidase originating from the extreme thermophile Thermotoga neopolitana has been cloned and expressed in Escherichia coli. The aim was to produce a thermostable enzyme that could be used to remove sugar residues from glucosylated natural products classified as flavonoids by applying a method combining extraction in hot pressurized water with enzymatic hydrolysis. The β-g

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Raoul Wallenberg Institute of Human Rights and Humanitarian Law Stora Gråbrödersgatan 17B, 222 22 Lund, Sweden | www.rwi.lu.se Call for Proposals (CFP) for Website Redesign Raoul Wallenberg Institute of Human Rights and Humanitarian Law Current website: www.rwi.lu.se Issue date: 16 February 2026 Proposal submission deadline: 5 March 2026 1. Background The Raoul Wallenberg Institute of Human Rights

https://rwi.lu.se/wp-content/uploads/2026/02/Call-for-Proposal-RWI-website-2026-published-16-Feb.pdf - 2026-05-07

Phenotypic plasticity in floral scent in response to nutrient, but not water, availability in the perennial plant Arabis alpina

Floral scent is an important mediator of plant–pollinator interactions. Multiple recent studies report ample intraspecific scent variation among populations and individuals. Yet, few studies have eastimated effects of phenotypic plasticity on floral scent in response to differing environmental factors. In this study, we investigated the effects of nutrient and water availability on floral scent in

Sevoflurane provides better haemodynamic stability than propofol during right ventricular ischaemia-reperfusion

OBJECTIVES: To assess whether sevoflurane provides better haemodynamic stability than propofol in acute right ventricular (RV) ischaemia-reperfusion. METHODS: Open-chest pigs (mean ± standard deviation, 68.8 ± 4.2 kg) anaesthetized with sevoflurane (n = 6) or propofol (n = 6) underwent 60 min of RV free wall ischaemia and 150 min of reperfusion. Haemodynamic parameters and blood flow in the 3 majo

Pulmonary Injury Following Intestinal Ischemia and Reperfusion in Rats

Popular Abstract in Swedish Intestinal ischemi/reperfusion (I/R) är ett potentiellt mycket allvarligt tillstånd som kan bero dels på direkt ocklusion av mesenteriella kärl, men även vara sekundärt till andra tillstånd med nedsatt visceral cirkulation, som exempelvis chock eller akut pankreatit. Trots korrekt och även initialt framgångsrik behandling av den bakomliggande orsaken till I/R-tillståndeIntestinal ischemia and reperfusion (I/R) is a potentially life-threatening condition, sometimes leading to a systemic inflammatory response and the potential development of the multiple organ dysfunction syndrome. The overall aim of the thesis was to study the effects of intestinal I/R on pulmonary function with special emphasis on removal of excess alveolar fluid, pulmonary endothelial barrier p

CO2 and O-3 effects on host plant preferences of the forest tent caterpillar (Malacosoma disstria)

Elevated levels of CO2 and O-3 affect plant growth and phytochemistry, which in turn can alter physiological performance of associated herbivores. Little is known, however, about how generalist insect herbivores respond behaviorally to CO2- and O-3-mediated changes in their host plants. This research examined the effects of elevated CO2 and O-3 levels on host plant preferences and consumption of f

Homeobox transcription factor muscle segment homeobox 2 (Msx2) correlates with good prognosis in breast cancer patients and induces apoptosis in vitro

Introduction: The homeobox-containing transcription factor muscle segment homeobox 2 (Msx2) plays an important role in mammary gland development. However, the clinical implications of Msx2 expression in breast cancer are unclear. The aims of this study were to investigate the potential clinical value of Msx2 as a breast cancer biomarker and to clarify its functional role in vitro. Methods: Msx2 ge

Metabolic Effects of Growth Hormone Replacement Therapy in Adults - with Special Reference to Insulin Sensitivity

Popular Abstract in Swedish Tillväxthormon (GH) är ett hormon som produceras och insöndras stötvis från hypofysen. GH-insöndringen styrs av stimulerande och hämmande signaler från hypothalamus, men hämmas även av sin egen insöndring. GH produceras under hela livet men mängden insöndrat hormon sjunker med stigande ålder. Under barn- och ungdomsåren har GH en viktig funktion att stimulera längdtillvA risk for premature atherosclerosis and increased cardiovascular mortality has been reported in adult patients suffering from growth hormone deficiency (GHD) and receiving conventional hormone substitution without growth hormone (GH) replacement. GHD patients are resistant to insulin, which is a potential risk factor for cardiovascular mortality. Insulin resistance can develop from an unfavourabl

Sources of Arachidonic Acid in Platelets, Bone, Marrow and Gastrointestinal Tract

This study investigates pathways by which the eicosanoid precursor pools in the platelets, bone marrow and the gastrointestinal (GI) mucosa are acquired and regulated, and in this context some aspects on the interaction between triglyceride (TG)-rich lipoproteins and platelets. 1. Platelets take up chylomicrons (CM) in vitro, the main part being sequestered in open canalicular system and not degr

En hållbar trädgårdsjord

Intresset för växter och att odla tycks öka i takt med intresset att leva mer hållbart. Att plantera i antingen en rabatt eller en kruka tillsammans med den mest anpassade jorden köpt i den närmaste trädgårdsbutiken är troligtvis en självklar del av processen. Studeras baksidan på jordsäcken närmare går det utläsa att jorden till största del består av torv. Torv är en fossil resurs med en bildningDrained peatlands in Sweden emit approximately 11 tons of carbon dioxide equivalents annually. Attempts to rewet to eliminate emissions have shown that the irreversible processes of peat oxidation in the form of peatland deposition makes it hard, since it instead greatly increases methane gas emissions. This study presents a literature review of the environmental consequences of peat and peatland

Neutrophil:lymphocyte ratio and cell-free DNA dynamics during excessive heat stress in occupational and experimental settings

Introduction Systemic inflammation is postulated to mediate heat stroke and heat-related organ injury, yet acute inflammatory responses among heat-stressed workers remains poorly understood. We aimed to describe neutrophil mobilisation and potential release of DNA during heat stress in multiple hot occupational settings and a controlled experimental setting. Methods Neutrophil:lymphocyte ratio (NL

SH2020

SH2020 1 STUDENT HANDBOOK 2020-21 Version 1.0 – August 2020 1 Welcome 1 Letter from the Director of Studies 3 About 4 Lund University 5 The Faculty of Social Sciences 6 Graduate School 7 Contact information 8 Studying at Graduate School 9 Graduate School – a brief history 10 Communication channels 12 Our Master’s programmes 13 Term 1 13 Term 2 14 Term 3 15 Term 4 16 Thesis preparation track 18 Lan

https://www.graduateschool.sam.lu.se/sites/graduateschool.sam.lu.se/files/2020-08/SH2020.pdf - 2026-05-09

Nätstationer - Potential för grönytor i Helsingborgs stad?

I Helsingborgs stad, likt i många andra större städer i Sverige, råder det platsbrist samtidigt som grönytor försvinner i takt med att nybyggnationer ökar. Helsingborgs stad har som vision att vara en skapande, pulserande, gemensam, global och balanserad stad för både människor och företag år 2035. Den nya urbaniseringstrenden ställer därmed krav på stadens uppbyggnad och planering. Vidare har gröIn Helsingborg, as in many other major cities in Sweden, there is a shortage of space as green space disappears while new construction increases. The municipality of Helsingborg has a vision to be a creative, vibrant, common, global and balanced city for both people and companies by 2035. The new urbanization trend places a demand on the city's construction and planning. Furthermore, greenery

Zircon growth during progressive recrystallization of Gabbro to Garnet Amphibolite, Eastern Segment, Sveconorwegian orogen

The interpretation of whether a dated metamorphic zircon generation grew during the prograde, peak or retrograde stage of a metamorphic cycle is critical to geological interpretation. This study documents a case at Herrestad, in the eastern part of the 1±0 Ga Sveconorwegian Province, involving progressive metamorphic recrystallization of gabbro to garnet amphibolite and associated behaviour of Zr-

Ion channels and electrical activity in vascular smooth muscle: Effects of calcium store depletion, cholesterol and cholesterol-lowering drugs.

Popular Abstract in Swedish Ateroskleros är en sjukdomsprocess vars grundläggande utveckling i blodkärlens väggar sannolikt börjar flera decennier innan insjuknandet i infarkt eller slaganfall inträffar. Som svar på endotelskada, inflammatoriska mediatorer eller tillväxtfaktorer i kärlet kommer glatta muskelceller att dela sig, migrera in mot blodbanan och börja syntetisera en helt ny uppsättning Smooth muscle cells (SMCs) in the vessel wall contract to regulate blood flow and pressure, a function essential for normal circulation through tissues. On the other hand, migration and proliferation of SMCs are important factors in vascular disease, such as atherosclerosis and restenosis following surgical dilatation. The conversion of the SMC to this role is marked by a modulation from contracti

Factors associated with meniscal body extrusion on knee MRI in overweight and obese women

Objective: To determine factors associated with higher degree of meniscal body extrusion in overweight and obese women at high risk of knee osteoarthritis (OA). Design: We used baseline data of the PRevention of knee Osteoarthritis in Overweight Females (PROOF) study, Netherlands, comprising overweight or obese women aged 50-60 years, free of clinical knee OA. All subjects completed a questionnair

Cell-Free DNA as a Biomarker in a Rodent Model of Chlorpyrifos Poisoning Causing Mitochondrial Dysfunction

Introduction: Organophosphates (OPs) are a major public health problem worldwide due to ease of access and high toxicity lacking effective biomarkers and treatment. Cholinergic agents such as OPs and carbamates are responsible for many pesticide-related deaths. While the inhibition of AChE is thought to be the main mechanism of injury, there are other important pathways that contribute to the over

Regional atmospheric cooling and wetting effect of permafrost thaw-induced boreal forest loss

In the sporadic permafrost zone of North America, thaw‐induced boreal forest loss is leading to permafrost‐free wetland expansion. These land cover changes alter landscape‐scale surface properties with potentially large, however, still unknown impacts on regional climates. In this study, we combine nested eddy covariance flux tower measurements with satellite remote sensing to characterize the imp