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How do orphan CdiA toxin modules affect the growth of bacteria and population heterogeneity?

Am I selfish? - Toxin edition Many bacteria encode for toxin-antitoxin (TA) pairs. The toxin is a stable protein that targets essential bacterial components. The antitoxin is an easily-degraded antidote that protects cells from poisoning themselves. If cells lose the TA genes, they cannot produce more of either toxin or antitoxin. The unstable antitoxin is degraded fast, and the stable toxin is n

Din kunskap, Min hemlighet - en uppsats om problematiken kring företagshemligheter och konkurrensklausuler

Utvecklingen som skett i Sverige de senaste decennierna, där vi har gått från industrisamhälle till kunskapssamhälle, från hierarki till platta organisationer och från maskin till hjärna har medfört ett ökat behov av skydd för arbetsgivare. Större ansvar, närmre relation med kunder samt indirekt kontroll från ledning och styrelse har vidgat arbetstagares utrymme i arbetslivet till att bl a fatta vSweden’s business-market has change a lot during the recent decades, where the society have gone from being industrialbased to knowledgebased, where organizations has gone from hierarchy to “flat” and now we use brains instead of machines. This has led to an increasing need of protection for employers. Greater responsibility, closer customer relationships and indirect control from management has e

2008 appl phys b 90 109

Microsoft Word - Bladh - APB 4415 - revised.doc Department of Physics LUP Lund University Publications Institutional Repository of Lund University Found at: http://www.lu.se This is an author produced version of a paper published in Applied Physics B: Lasers and Optics This paper has been peer-reviewed but does not include the final publisher proof-corrections or journal pagination. Citation for t

https://www.lub.lu.se/en/sites/lub.lu.se.en/files/2008_appl_phys_b_90_109.pdf - 2026-05-10

Predictors of Lymph Node Metastasis in Primary Breast Cancer - Risk Models for Tailored Axillary Management

Populärvetenskaplig sammanfattning1,7 miljoner nya fall av bröstcancer diagnosticeras årligen i världen. Bröstcancer är kvinnans vanligaste tumörsjukdom och i västvärlden samt Sverige kommer var åttonde till var nionde kvinna att insjukna under sin livstid. Överlevnaden efter bröstcancer är bland de högsta i världen i Sverige, med femårsöverlevnad på cirka 90%. För de kvinnor som diagnosticeras i Most patients with breast cancer present with low-risk tumors, node-negative disease, and excellent prognosis. For these patients, routine axillary nodal staging by sentinel lymph node biopsy (SLNB) has no therapeutic benefit. For patients with limited sentinel lymph node metastasis, completion axillary nodal dissection is controversial. Furthermore, those with heavy-burden metastasis could benefi

LU-gemensamt Mejlutskick Nr 38-2020-v48

NYTT FRÅN LUNDS UNIVERSITET Mejlutskick på svenska och engelska som vänder sig till fakultetskommunikatörer vid Lunds universitet för vidarespridning i fakultets- och institutionskanaler – Nr 38 v 48 - 2020. CORONARELATERAT Undervisning och examination ska övergå ännu mer till digitalt Smittspridningen ökar i hela samhället och från den 24 november gäller i Sverige att allmänna sammankomster och o

https://www.cec.lu.se/sites/cec.lu.se/files/2021-01/LU-gemensamt%20Mejlutskick%20Nr%2038-2020-v48.pdf - 2026-05-10

Bradykinin receptors and signal transduction pathways in human fibroblasts : Integral role for extracellular calcium

Bradykinin receptors have been identified in human gingival fibroblasts; the primary signal transduction pathways and their dependence on calcium have been characterized. Binding data revealed a calcium-independent binding of bradykinin to the cell membrane with a receptor density of 25,000 receptors per cell and a K d of 1.6 nM. The bradykinin receptor-mediated activation of phospholipase C (PLC

CPAP may promote an endothelial inflammatory milieu in sleep apnoea after coronary revascularization

Background: Continuous positive airway pressure (CPAP) has failed to reduce cardiovascular risk in obstructive sleep apnoea (OSA) in randomized trials. CPAP increases angiopoietin-2, a lung distension-responsive endothelial proinflammatory marker associated with increased cardiovascular risk. We investigated whether CPAP has unanticipated proinflammatory effects in patients with OSA and cardiovasc

Trust in researchers and researchers' statements in large carnivore conservation

Human–wildlife interactions occur when humans and wildlife overlap in the same landscapes. Due to the growing human population, the number of interactions will continue to increase, and in some cases, develop further into social conflicts. Conflicts may occur between people disagreeing about wildlife conservation or arguing over which wildlife management measures should be taken. Social conflicts

Plasma Alkylresorcinols is an objective biomarker for gluten intake in young children

BackgroundAlkylresorcinols are a well-established biomarker for whole grain intake. There is evidence suggesting that total plasma alkylresorcinol concentration may also be used as a biomarker for gluten intake in adults.ObjectiveThe aim of the study was to evaluate if total alkylresorcinol concentration is a valid biomarker for gluten intake in young children.MethodsNon-fasting plasma alkylresorc

Plasma copeptin as a predictor of kidney disease

Background: Plasma copeptin, a marker of vasopressin, is associated with renal function decline in the general population. Our aim was to study the links between elevated copeptin and future risk of kidney disease.Methods: Copeptin was measured in a sample of the Malmö Preventive Project (MPP) Reinvestigation (n = 5158) and in the Malmö Diet and Cancer Cardiovascular Cohort (MDC-CC) (n = 5162). Ac

The PDGF pathway in breast cancer is linked to tumour aggressiveness, triple-negative subtype and early recurrence

Purpose: The platelet-derived growth factor (PDGF) signalling pathway is often dysregulated in cancer and PDGF-receptor expression has been linked to unfavourable prognostic factors in breast cancer (e.g. ER negativity, high Ki67 and high grade). This study aimed to evaluate the expression of PDGFRα, PDGFRβ and ligand PDGF-CC in breast cancer in relation to molecular subtypes and prognosis. Method

Effective treatment of gut barrier dysfunction using an antioxidant, a PAF inhibitor, and monoclonal antibodies against the adhesion molecule PECAM-1.

BACKGROUND: Oxygen free radicals (OFRs), platelet activating factor (PAF), cell adhesion molecules, and transmigration of polymorphonuclear leukocytes through the gut barrier are probably all essential in the development of gut barrier dysfunction following intestinal ischemia and reperfusion (I/R). Pretreatment and early treatment of I/R with the OFRs-scavenger (NAC), the PAF inhibitor lexipafant

Combined effect of low-penetrant SNPs on breast cancer risk.

Background:Although many low-penetrant genetic risk factors for breast cancer have been discovered, knowledge about the effect of multiple risk alleles is limited, especially in women <50 years. We therefore investigated the association between multiple risk alleles and breast cancer risk as well as individual effects according to age-approximated pre- and post-menopausal status.Methods:Ten previo

Optimization, evaluation, and characterization of a hollow fiber supported liquid membrane for sampling and speciation of lead(II) from aqueous solutions

Hollow fiber supported liquid membrane sampling and speciation of lead(II) from aqueous solution using a selective carrier (Kelex 100) is studied. An optimization of different variables affecting permeation performance (chemical conditions of the sampling module - pH, concentration and nature of the acceptor phase, extractant concentration; membrane impregnation form; sampling time; and hollow fib

Experimental and Theoretical Study of Rack Storage Fires

Popular Abstract in Swedish En experimentell och teoretisk studie kring bränder i varulager i både modell och verklig skala har genomförts. Teoretiska modeller för att beräkna flamhöjder, gas temperaturer, gas hastigheter och värmeflöde inuti spalterna mellan de lagrade varorna presenteras. Modellerna kan t ex användas för att beräkna tid till utlösning av olika sprinklers som används för att skydA theoretical and experimental study of rack storage fires and responsiveness of sprinklers is presented. Free-burn tests with non-combustible and combustible material were carried out in reduced scale with verification in large scale. Formulas for in-rack flame height, excess gas temperature, gas velocity and heat flux to storage walls are provided. The formulas include overall heat release rate,

Polymer Gels and their Interactions with Ionic Surfactants

Popular Abstract in Swedish Polymergeler och deras interaktioner med joniska surfaktanter. Olika typer av hydrofoba polymerer och hydrophobmodifierade polymerer tvärbinds kemisk till geler. Dessa geler tillhör gruppen responsiva geler, vilket betyder att gelerna ändrar sin volym under yttre påverkan. Gelernas volymändring studeras vid tillsats av olika joniska surfaktanter, vid tillsats av saltThe response on chemically crosslinked gels and polymer solutions on the addition of ionic surfactants and/or addition of salt at different temperatures have been studied. All polymers studied are water soluble and slightly hydrophobic or hydrophobically modified. Because of their hydrophobicity the polymers have a strong tendency to associate, both with themselves and with surfactants. Another i

Charged Polymers at Spherical Surfaces

Two separate topics in the area of colloidal chemistry have been investigated by the use of molecular modeling: the structural properties of polyion?macroion complexes and of diblock polyampholyte brushes. The main results were obtained by the use of Monte Carlo simulation in the framework of the primitive model, and in the case of polyampholyte brushes the simulation results were also complemente

Master in Digital Architecture and Emergent Futures

25-29 May 2026 School of Architecture at Lund University invites you to presentation for degree project in Digital Architecture and Emergent Futures (ASEM01) on the 25-29 May 2026.The presentations are public and take place in Black Box, A-building, Klas Anshelms väg 16, 223 62 Lund.  Cesar Andres Velando GarciaDue to the climate crisis we are facing, we can no longer consider current construction

https://www.architecture.lth.se/education/degree-projects/master-digital-architecture-and-emergent-futures-26-28-may-3-june-2025 - 2026-05-09

Cocky prey swim away: predator-induced exposure and migratory tendency in a common cyprinid, roach (Rutilus rutilus)

Hellre fly än illa fäkta ”Hemma är där man sist satte sig” som vårtsvinet Pumbaa i filmen Lejonkungen så vackert myntade. Men många är nog de, vilka associerar ordet flytta med ett lägenhetsbyte från en stadsdel till en annan, från större till mindre, från mindre till större. Att flytta är dock inte något som är unikt för människan, långt ifrån. Inom biologin används termen migration, ett fenomeAbstract In nature, a majority of migratory populations are composed of a mixture of both seasonal migrants and year-round residents, a phenomenon known as partial migration. It is of great importance to identify the factors causing the variation in individual decisions of whether or not to migrate. Partly for a more profound understanding of the evolution behind animal migration, and moreover th