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In free flap surgery, restored blood flow following a lengthy ischaemic period may lead to necrosis as a result of ischaemia/reperfusion (IR) injury. This injury comprises both proinflammatory and prothrombotic events, where the tissue factor/factor VIIa complex probably has a key role. Active site-inactivated factor VIIa (FFR-rFVIIa) exerts an antithrombotic effect by binding to tissue factor wit

The effects of 2,3-butanedione monoxime (BDM) on intracellular Ca2+ transient and cross-bridge function were studied in frog single fibres from the anterior tibialis muscle of Rana temporaria (sarcomere length, 2.2 m; temperature, 24 C). The fluorescent dye fluo-3 was used to monitor the intracellular free calcium concentration ([Ca2+i) during isometric contractions. BDM (15 m M) reduced the ampli

Water-soluble aggregates based on two polyion-surfactant ion "complex salts", consisting of hexadecyltrimethylammonium (C16TA(+)) and polyacrylate (PA(-)) with either 25 or 6000 repeating units, with added nonionic surfactant octaethylene glycol monododecyl ether (C12E8) have been investigated. A previous phase study has shown that added C12E5 or C12E8 can solubilize complex salts in aqueous syste

Bacillus macerans cyclodextrin glycosyltransferase (CGTase) was used to convert dodecyl-β-maltoside (DDM) to dodecyl-β-maltooctaoside (DDMO) using α-cyclodextrin (α-CD) or starch as glycosyl donors. At 300mM α-CD, varied DDM concentration and 60°C, the reaction obeyed Michaelis-Menten kinetics with a K(m) value of 18mM and a V(max) value of 100U/mg enzyme. However, at 25mM α-CD the reaction

The former storage ring CRYRING has been shipped from the Manne Siegbahn Laboratory in Stockholm to Darmstadt as a Swedish in-kind contribution to FAIR. At its new location downstream of ESR all ion species presently accessible in ESR can be transferred to CRYRING, in which ions with rigidities between 1.44 and 0.054 Tm can be stored. The original Swedish layout has been modified by reconfiguring

In order to study the limitations and possibilities of age estimation based on tooth wear of skeletal remains from wild boar, 315 mandibles from five different populations of wild boar from Poland, Germany and Sweden were analysed. Asymmetric tooth wear between the right and left mandibles was found to be rare and no systematic difference in tooth wear between males and females (less than 36 month

Smart polymers (SP) have become one important class of polymers and their applications have been increasing significantly. Last two to three decades have witnessed explosive growth in the subject. SP which are also known as stimuli-responsive soluble insoluble polymers or environmentally sensitive polymers have been used in the area of biotechnology, medicine and engineering. The present review is

Different conceptions exist regarding the epidemiology and prognosis of liposarcoma, and several classification systems are in use. We analyzed a population-based, 25-year series of 43 patients with liposarcoma of the extremity or trunk wall. Follow-up was complete. The annual incidence was 0.12/10(5). The thigh was the most common location. One of 6 tumors was subcutaneous. Deep-seated tumors wer

Barnase folds cooperatively via an intermediate, followed by a rate-limiting transition state. We have probed possible movements of the intermediate and transition state on the energy landscape with changing temperature, from the temperature dependence of -values. These measure interaction energies at the level of individual residues. The results suggest that single destabilizing mutations can red

Statins are known to exert a number of biological effects apart from reducing cholesterol synthesis. The results of recent studies indicate that patients treated with pravastatin have a lower prevalence of diagnosed Alzheimer’s disease (AD). These observations prompted us to examine the effects of pravastatin on Alzheimer’s peptide (Aβ1–42)-induced pro-inflammatory activation in the human glioma c

The alkaline sphingomyelinase (SMase) was first found in rat intestinal brush border. The important roles of this enzyme in digestion of sphingomyelin and in mucosal cell proliferation have been suggested. In the present work, the distribution of the alkaline SMase in the tissues of human beings and animals have been studied. By assaying the enzyme activity in human biopsy samples, we found that t

The influence of external nitrogen (N) on carbon (C) allocation and processes related to phosphorus (P) metabolism were studied in monoxenic arbuscular mycorrhiza (AM) cultures of Daucus carota. Fungal hyphae of Glomus intraradices proliferated from colonized roots growing on solid medium into C-free liquid minimal medium with two different N and P levels. Furthermore, we exposed the colonized roo

Page 1 of 2 Department of Biology Education- Bachelor's and Master's level COURSE ANALYSIS Date 2025-01-27 Main Teacher: Johannes Rousk Number of students: 20 Number of answers: 16 Grades: 14 VG, 6G Course Analysis: Soil and Plant Ecology, BIOR78, autumn semester 2024 Summary of the course evaluation The grade for the entire course was 3.5, which is significantly lower than normal and was due to t

https://www.lunduniversity.lu.se/sites/www.lunduniversity.lu.se/files/d6d0298eb2c37cb5dc59a46326c806776d49dc19_BIOR78_2024_kursanalys.pdf - 2026-05-10

BACKGROUND: Gout is the most common inflammatory arthritis with a rising prevalence around the globe. While educational inequalities in incidence and prevalence of gout have been reported, no previous study investigated educational inequality in mortality among people with gout. The aim of this study was to assess absolute and relative educational inequalities in all-cause and cause-specific morta

The new Swedish Library Act, which took effect in 2014, states in paragraph 2 that libraries in the public library system shall promote the development of a democratic society by contributing to the transfer of knowledge and the free formation of opinions. In recent years several debates have surfaced in the media concerning the democratic mission by public librarians and public libraries, in rega

Microsoft Word - Bladh - APB 4415 - revised.doc Department of Physics LUP Lund University Publications Institutional Repository of Lund University Found at: http://www.lu.se This is an author produced version of a paper published in Applied Physics B: Lasers and Optics This paper has been peer-reviewed but does not include the final publisher proof-corrections or journal pagination. Citation for t

https://www.lub.lu.se/en/sites/lub.lu.se.en/files/2008_appl_phys_b_90_109.pdf - 2026-05-10

BACKGROUND: Community-acquired pneumonia (CAP) is a leading cause of hospitalization worldwide. Bed rest with low levels of physical activity is common during periods of hospitalization and leads to functional decline as well as increased risk of complications. The aim of this study is to assess the effect of supervised physical training during hospitalization with CAP compared with standard usual

Precapillary pulmonary hypertension (PHprecap) is a condition with elevated pulmonary vascular pressure and resistance. Patients have a poor prognosis and understanding the underlying pathophysiological mechanisms is crucial to guide and improve treatment. Ventricular hemodynamic forces (HDF) are a potential early marker of cardiac dysfunction, which may improve evaluation of treatment effect. The

Inflammatory responses play a vital role at different stages of colorectal carcinogenesis. C-type lectins mediate inflammatory/immune responses and participate in immune escape of pathogens and tumors. Our study aimed to evaluate the correlation between polymorphisms in three C-type lectin genes, CD209, MBL2 and REG4, and colorectal cancer (CRC) risk and clinical outcome. We genotyped 15 potential

Recent advances in nanotechnology and the accompanying development oftechniques that operate and manipulate systems on the micro- and nanometer scale have driven the development of stochastic thermodynamics. This isa theory that can describe small systems far from equilibrium, where the fluctuations are of the same order of magnitude as the mean values. Stochasticthermodynamics can be used to prov