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Activated porcine embryonic brain endothelial cells induce a proliferative human T-lymphocyte response

Transplantation of allogeneic embryonic neural tissue is a potential treatment for patients with Parkinson's and Huntington's diseases. The supply of human donor tissue is limited, and alternatives such as the use of animal (e.g., porcine) donor tissue are currently being evaluated. Before porcine grafts can be used clinically, strategies to prevent neural xenograft rejection must be developed. Kn

Antileukoproteinase - Modulation of neutrophil function and therapeutic effects on anti-type II collagen antibody-induced arthritis

Objective. Antileukoproteinase (ALP) is a physiologic inhibitor of granulocytic serine proteases. The present study was undertaken to investigate its therapeutic benefit in an antibody-transfer model of erosive polyarthritis and to elucidate its potential to interfere with immune complex-dependent inflammatory pathways. Methods. Arthritis development was induced in male (BALB/c x B10.Q)F-1 mice by

Immune responses following meningococcal serogroups A, C, Y and W polysaccharide vaccination in C2-deficient persons: Evidence for increased levels of serum bactericidal antibodies.

Complement C2 deficiency (C2D) is associated with immunological diseases and increased susceptibility to invasive infections caused by encapsulated bacteria such as Neisseria menigitidis. In this study we evaluate the immunogenicity of vaccination against N. menigitidis in C2D. C2D patients (n=22) and controls (n=52) were given a tetravalent meningococcal polysaccharide vaccine. Serum bactericidal

γ-globulins prepared from sera of multiparous women bind anti-HLA antibodies and inhibit an established in vivo human alloimmune response

It has previously been shown that sera from multiparous women have increased levels of anti-idiotypic antibodies specific for anti-HLA molecules. γ-Globulins prepared from these sera may be superior to commercial preparations of intravenous γ-globulin (IVIg) for inhibiting HLA alloimmunization. To test this, F(ab′)2 fragments prepared from either commercial IVIg or from the sera of men or multipar

TFPI-2 protects against gram-negative bacterial infection

Tissue factor pathway inhibitor-2 (TFPI-2) has previously been characterized as an endogenous anticoagulant. TFPI-2 is expressed in the vast majority of cells, mainly secreted into the extracellular matrix. Recently we reported that EDC34, a C-terminal peptide derived from TFPI-2, exerts a broad antimicrobial activity. In the present study, we describe a previously unknown antimicrobial mode of ac

Plasmodium falciparum transmission based on merozoite surface protein 1 (msp1) and 2 (msp2) gene diversity and antibody responses in Ibadan, Nigeria

Background: Nigeria is a major contributor to the global malaria burden. The genetic diversity of malaria parasite populations as well as antibody responses of individuals in affected areas against antigens of the parasite can reveal the transmission intensity, a key information required to control the disease. This work was carried out to determine the allelic frequency of highly polymorphic Plas

C-terminal TFPI-1-derived peptides: their evolutionary host defense functions

Antimicrobial peptides (AMPs) are evolutionarily ancient molecules. They are essential innate immune response molecules that protect organisms from invading pathogens. Tissue factor pathway inhibitors (TFPI-1 and TFPI-2) C-terminal derived peptides exert host defense mechanisms against microbes. Studies showed that in human plasma, C-terminal TFPI-1 and -2 derived peptides mediate bacterial killin

Novel peptide ligand with high binding capacity for antibody purification

Small synthetic ligands for protein purification have become increasingly interesting with the growing need for cheap chromatographic materials for protein purification and especially for the purification of monoclonal antibodies (mAbs). Today, Protein A-based chromatographic resins are the most commonly used capture step in mAb down stream processing; however, the use of Protein A chromatography

4. relativdosimetri

Dosimetry Relativdosimetri Crister Ceberg Medical Radiation Physics Lund University Sweden Reference geometry Treatment unit Ion chamber => monitor units, UR Measurement point => absorbed dose, DR Water tank 𝐷𝑅 = 𝐷𝑅 𝑈𝑅 Treatment geometry • Distance from source, f • Collimator setting, c • Treatment depth in patient, z Relative dosimetry Reference geometry Treatment geometry fR f DDR z zR ccR

https://www.msf.lu.se/sites/msf.lu.se/files/4._relativdosimetri.pdf - 2026-05-07

On the M*-BCJR and LISS Algorithms for Soft-Output Decoding of Convolutional Codes

To communicate reliably over noisy wireline or wireless channels, algorithms that add redundancy are used to help reconstruct the transmitted sequence at the receivers. Such error control coding algorithms are today used in all digital communication systems. Optimum decoding algorithms such as the Viterbi and BCJR have very good performances but often too high complexity. Therefore, less complex s

Mos halvtidskontroll - variabellista 2019-02-20

MOS Variabellista inkl frekvenser - Halvtidskontroll (2018-06-13) Sida 1 av 50 Nr Name Format Variable label File Checked #B #BB Deltagare 1 lopnrMOS Numeric Löpnummer vid MOS baslinjeundersökning (Numerisk) MOS_Deltagare_halvtid.savAD 1326 1321 2 lopnrMOS_str8 String Löpnummer vid MOS baslinjeundersökning (Sträng, utan mellanstreck)MOS_Deltagare_halvtid.savAD 1326 1321 3 lopnrMOS_str9 String Löpn

https://www.malmo-kohorter.lu.se/sites/malmo-kohorter.lu.se/files/2024-03/mos_halvtidskontroll_-_variabellista_2019-02-20.pdf - 2026-05-07

Cliticisation in the acquisition of French as L1 and L2

The intense debate on continuity in child grammars has largely focused on the existence of Functional Categories (FCs) in early grammars despite differences in language use with adults (e.g., omissions, word order errors, lack of case marking). Simplified, the major theoretical explanations for these properties range from Maturational accounts (Radford 1990 and later) claiming an initial absence o