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Traveling Architects – A New Way of Herding Cats

Making software developers work towards a common goal may be likened to herding cats. If we further spread developers around the globe, we run increased risks of being unable to design and impose coherent software architectures on projects, potentially leading to lower quality of the resulting systems. Based on our experiences in a large, distributed research and development project, PalCom, we pr

Threat to fixation and vision-related quality of life in patients with open-angle glaucoma

Purpose: We aimed to investigate the association between overlapping threat to fixation (TTF) and vision-related quality of life (VRQoL) in patients with manifest open-angle glaucoma (OAG). Methods: Overall, 316 patients with manifest OAG were recruited from the glaucoma outpatient department of Skåne University Hospital, Malmö, Sweden, between April and December 2018. VRQoL was assessed using the

Long-term changes in eating-related problems and quality of life in children with overweight and obesity attending a 10-week lifestyle camp

Eating-related problems (e.g., binge eating (BE)) and impaired quality of life (QoL) is more prevalent in children with overweight and obesity. This study aimed to investigate changes in self-reported overeating (OE), BE, and QoL in children with overweight or obesity attending multicomponent 10-week lifestyle camps with a 52-weeks follow-up. Additionally, the study sought to investigate whether s

Quality of life in patients with chronic alveolar hypoventilation

Measurements of health-related quality of life (HRQL) have not been reported in patients with chronic alveolar hypoventilation (CAH) before starting home mechanical ventilation. The purpose of this study was to investigate quality of life in a population of such patients. Forty-four consecutive patients with CAH due to previous polio, scoliosis, healed pulmonary tuberculosis or neuromuscular disea

A combination of two or more unhealthy lifestyle factors is associated with impaired physical and mental health in patients with spondyloarthritis : a cross-sectional study

Background: There is increasing knowledge of how individual lifestyle factors affect patients with spondyloarthritis, while studies exploring the combination of unhealthy lifestyle factors are lacking. Thus, our aim was to study the frequency of two or more unhealthy lifestyle factors and their associations with physical and mental health in patients with spondyloarthritis (SpA). Methods: A popula

Femoral neck fractures. Aspects on treatment and outcome.

Popular Abstract in Swedish Höftfraktur är en vanlig skada, som huvudsakligen drabbar äldre kvinnor, och oftast orsakas av ett ringa våld. Det är vanlig orsak till funktionsnedsättning, sjuklighet och dödlighet hos de äldre. Både incidensen (antal nya fall per antal innevånare och år) av höftfrakturer och det totala antalet har ökat de senaste årtiondena. Höftfrakturer medför stora kostnader för sHip fractures are a common cause of morbidity and mortality in elderly patients, with a high risk of functional impairment and institutionalization. The incidence and number of hip fractures have increased during the recent decades and hip fractures consume considerable health-care resources. The incidence of hip fractures in Malmö, Sweden, 1992–95, is described in Paper I. The annual incidence pe

Health-Related Quality of Life of Patients Receiving Low-toxicity Immunosuppressive Regimens:. A Substudy of the Symphony Study

Objective. To evaluate health-related quality of life (HRQoL) in patients with different low-toxicity regimens post-transplantation. Methods. One hundred fifty-six patients were randomized to standard-dose cyclosporine A (CsA), mycophenolate mofetil, and corticosteroids or daclizumab induction, mycophenolate mofetil, and corticosteroids with a low dose of CsA, tacrolimus (Low-Tac), or sirolimus. S

A randomized controlled trial of haemoglobin normalization with epoetin alfa in pre-dialysis and dialysis patients

Background. Partial correction of renal anaemia with erythropoietin improves quality of life (QoL). We aimed to examine if normalization of haemoglobin with epoetin alfa in pre-dialysis and dialysis patients further improves QoL and is safe. Methods. 416 Scandinavian patients with renal anaemia [pre-dialysis, haemodialysis (HD) and peritoneal dialysis patients] were randomized to reach a normal ha

Long-term follow-up after otitis media in childhood

Popular Abstract in Swedish Bakgrund: Öroninflammation är vanligt förekommande i barnaåren. De flesta barn har haft minst en episod med akut varig öroninflammation (AOM) och/eller en period med vätska i mellanörat (SOM) före skolstart. De flesta får enstaka episoder, frekvensen av AOM avtar i 2-års åldern och frekvensen av SOM avtar före skolstart. Efter en AOM episod är det vanligt att man under Objective: Most preschool children have suffered from at least one episode of acute otitis media (AOM) and/or secretory otitis media (SOM). Some children have frequent AOM episodes and/or prolonged and recurrent episodes of secretory otitis media (SOM). The long-term out-come and sequelae are not fully clarified. Subjects and methods: Out of a birth cohort followed to the age of 3 years, 12 child

Aspects of autoantibody epitopes in type 1 diabetes

Popular Abstract in Swedish I Sverige insjuknar två barn i autoimmun diabetes (typ 1 diabetes) varje dag. Typ 1 diabetes (T1D) är en kronisk autoimmun sjukdom som kan få livshotande konsekvenser vid utebliven behandling. Sverige har den högsta incidensen av T1D i hela världen efter Finland. Förutom att den delvis är ärftlig vet man inte vilken eller vilka faktorer som triggar sjukdomen. Sedan mittType 1 diabetes (T1D) is strongly associated with autoantibodies against insulin (IAA), glutamic acid decarboxylase 65 (GADA), insulinoma-associated protein 2 (IA-2A) and the most recently identified zinc T8 transporter (ZnT8A). Together or alone, they are important both to predict T1D and to classify diabetes at the time of clinical onset. The single nucleotide polymorphism (SNP) rs13266634 in th

Chinese women living with cervical cancer- Health-related Quality of Life, Sense of Coherence, lived experience

Due to the unavailability of culture-appropriate measurements of health-related quality of life (HRQOL) in China, knowledge about the HRQOL of women with cervical cancer, particularly in Mainland China, is poor. Such knowledge is greatly needed to inform nursing practice. Thus the main aim of this thesis was to investigate longitudinally the HRQOL trajectory in Chinese women from when cervical can

Hospital-based home care for children with cancer: Feasibility and psychosocial impact on children and their families

Background To assess the feasibility and psychosocial impact of a hospital-based home care (HBHC) program for children with cancer. Procedure A HBHC program was carried out with 51 children (018 years) with cancer to assess its feasibility in terms of satisfaction, care preferences, safety, and cost. A controlled trial was conducted to assess children's health-related quality of life (HRQOL) using

Is intermittent androgen-deprivation therapy beneficial for patients with advanced prostate cancer?

Use of intermittent androgen-deprivation therapy (IADT) in patients with prostate cancer has been evaluated in several studies, in an attempt to delay the development of castration resistance and reduce side-effects associated with ADT. However it is still not clear whether survival is adversely affected in patients treated with IADT. In this review, we explore the available data in an attempt to

The UP-TECH project, an intervention to support caregivers of Alzheimer's disease patients in Italy : Preliminary findings on recruitment and caregiving burden in the baseline population

Objectives: The paper describes recruitment results and characteristics of the UP-TECH clinical trial sample, including level of care services use, informal caregiver burden and its determinants.Methods: UP-TECH is designed to test innovative care solutions for community-dwelling patients with moderate stage Alzheimer's disease and their caregivers in Italy. Four hundred and fifty patient-caregive

Palliative oxygen for chronic breathlessness : What new evidence?

Purpose of review Supplemental oxygen improves survival in patients with chronic obstructive pulmonary disease (COPD) and severe hypoxaemia, but the effect of oxygen therapy in mild or moderate hypoxaemia to reduce symptomatic chronic breathlessness remains unclear. This review provides an overview of recent evidence about the role of oxygen therapy for the relief of chronic breathlessness in adva

Tjänstefelsbestämmelsen - ur ett kriminalpolitiskt perspektiv

Inledning Tjänstefelsbestämmelsen återfinns i 20:1 BrB och har diskuterats kriminalpolitiskt under lång tid, vilket medfört att tjänstefelsansvarets stränghet varierat. Frågeställningen blir då vilka argument som framförts för och mot kriminalisering av tjänstefelsgärningar och vilka kriminaliseringsbegränsande principer som kan anföras för och mot kriminalisering av tjänstefelsgärningar. Syftet mIntroduction The misconduct provision is found in 20:1 in the Penal Code and has been discussed in criminal policy for a long time, resulting in that the severity of the misconduct responsibility has varied. The question that follows is what arguments that are presented for and against the criminalization of misconduct offences and which criminalization limiting principles that can be set in contr

Method Development for Fractionation of Milk Fat Globules -For improvement of cream functionality

In recent years, different methods for fractionation of native milk fat globules with respect to particle size have been developed. This has been done in order to investigate if the size of the fat globules have any impact on the product functionality. The purpose of this master thesis was to develop a method for fractionation of native milk fat globules with respect to particle size and with focu

Soil Water Modelling In Arid/Semiarid Regions of Northern China Using Land Information System (LIS) - A Minor Field Study in Shiyang River Basin

At present China suffers from severe desertification or land degradation. About 27% of the total territory was exposed in 2004, mainly the northern provinces. Consequences of desertification, such as floods or sandstorms, require huge effort and financial assets. Soil moisture understanding plays a key role in combating desertification and is necessary in order to implement a sustainable water man

Vi gör det mesta materialet själva - En studie om behovet av pedagogiska läromedel i Musikproduktion

Denna studies syfte är att identifiera om det finns ett behov av att utforma läromedel för lärare i Musikproduktion, och hur lärare arbetar med denna kurs idag. Detta har undersökts dels med en enkätstudie samt kvalitativa intervjuer med två pedagoger som undervisar i Musikproduktion på två gymnasieskolor. Litteraturgenomgången belyser vilka behov som finns i skolan idag där perspektiv på elever, The aim of this study is to identify if there is a need to produce educational materials for teachers in “Musikproduktion”, and how teachers work with this course today. This has been done partly through a survey study and qualitative interviews with two teachers in music production in two Swedish upper secondary schools. The literature review explores the need that exists in schools today where p