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A Single Nucleotide Polymorphism Associates With the Response of Muscle ATP Synthesis to Long-Term Exercise Training in Relatives of Type 2 Diabetic Humans
OBJECTIVE-Myocellular ATP synthesis (fATP) associates with insulin sensitivity in first-degree relatives of subjects with type 2 diabetes. Short-term endurance training can modify their fATP and insulin sensitivity. This study examines the effects of moderate long-term exercise using endurance or resistance training in this cohort. RESEARCH DESIGN AND METHODS-A randomized, parallel-group trial tes
Transition Quadrupole Moments in the Superdeformed Band of 40Ca
The transition quadrupole moments Q(t) for the superdeformed band in Ca-40 have been determined through thin-target Doppler-shift attenuation analyses. A best-fit value of Q(t)=1.30+/-0.05 e b is obtained when a single value is assumed for the entire band. Fitting separate quadrupole moments for in-band transitions decaying from the high-spin states and the presumably admixed low-spin states resul
Long-term efficacy and safety comparison of liraglutide, glimepiride and placebo, all in combination with metformin in type 2 diabetes: 2-year results from the LEAD-2 study
Lung function, insulin resistance and incidence of cardiovascular disease: a longitudinal cohort study.
Objectives. To explore whether a reduced lung function is a risk factor for developing diabetes and insulin resistance (IR), and whether such relationship contributes to the largely unexplained association between lung function and incidence of cardiovascular disease (CVD). Design. Forced vital capacity (FVC) was assessed at baseline. Incidence of diabetes and IR [according to the homeostasis mod
Altered endothelial/pericyte ratio in Goto-Kakizaki rat retina
The Goto-Kakizaki (GK) rat represents a model of hereditary non-insulin-dependent diabetes mellitus (NIDDM), characterized by nonobesity, mild hyperglycemia from early life, impaired glucose tolerance test results, and a markedly defective insulin response to glucose. The rats develop signs of both nephropathy and neuropathy, but, to our knowledge, retinal changes have not been reported so far in
Does Imaging Modality Used for Percutaneous Renal Access Make a Difference? A Matched Case Analysis
Objective: To assess perioperative outcomes of percutaneous nephrolithotomy (PCNL) using ultrasound or fluoroscopic guidance for percutaneous access. Methods: A prospectively collected international Clinical Research Office of the Endourological Society (CROES) database containing 5806 patients treated with PCNL was used for the study. Patients were divided into two groups based on the methods of
Jesper Falkheimer
Professor Kontaktinformation E-post: jesper [dot] falkheimer [at] iko [dot] lu [dot] se Telefon: +46 42 35 66 50 Mobil: +46 72 728 22 14Organisation Institutionen för kommunikation WebbplatsJesper Falkheimers profil i Lunds universitets forskningsportal Publikationer Visar av publikationer. Sorterade efter år och sen titel. Filtrera efter typ AllaArtikel i tidskriftArtikel i uppslagsverkBokBokrece
https://www.cencip.lu.se/jesper-falkheimer - 2026-04-18
Therese Nilsson
Professor Kontaktinformation E-post: therese [dot] nilsson [at] nek [dot] lu [dot] se Telefon: +46 46 222 46 43Organisation Nationalekonomiska institutionen Rumsnummer: Alfa1:4101 Hämtställe: 10 WebbplatsTherese Nilssons profil i Lunds universitets forskningsportalPersonlig webbplats:https://sites.google.com/site/nilssonltherese/homeAndra roller Profilområdesmedlem LU profilområde: Proaktivt åldra
https://www.ehl.lu.se/therese-nilsson - 2026-04-18
Whole body heat balance and local insulation required to prevent extremity cooling in extremely cold environments
IntroductionLocal cooling in winter conditions is a sensitive and early warning of whole body cooling. Previous studies showed that the equilibrium temperature for the 5th finger is strongly affected by both temperature and insulation. The international standard ISO 11079 is used to calculate clothing insulation required for the whole body based on heat balance equations. However, it does not prov
Changing management of gallstone-related disease in pregnancy–a retrospective cohort analysis
Objectives: Gallstone-related disease is the second most common non-obstetric cause, following appendicitis, for acute abdomen in pregnancy. This study aimed to investigate treatment strategies, changes over time and outcome. Materials and methods: All consecutive patients with symptomatic gallstone-related disease during pregnancy admitted to Skane University hospital in Lund and Malmö 2001–2015
Neuropeptide Y, peptide YY and C-terminal fragments release histamine from rat peritoneal mast cells
1. Neuropeptide Y (NPY) and peptide YY (PYY) seem to act on at least two receptor subtypes, Y1 and Y2. The Y1-receptor requires the whole C-terminally amidated NPY/PYY molecule whereas the Y2-receptor in addition recognizes C-terminal fragments of the two peptides. The present study was designed to elucidate whether NPY and related peptides were able to release histamine from isolated peritoneal m
Propylthiouracil-induced hypothyroidism in coho salmon, Oncorhynchus kisutch : Effects on plasma total thyroxine, total triiodothyronine, free thyroxine, and growth hormone
Thyroid hormones transiently increase during parr-smolt transformation in coho salmon, Oncorhynchus kisutch, and are believed to trigger morphological, physiological, behavioural, and neural changes. The effectiveness of propylthiouracil (PTU) to induce hypothyroidism in smolting coho salmon was determined by immersing coho salmon, Oncorhynchus kisutch, in 30 mg 1-1 PTU from May 1, two weeks prior
Acceptability of HIV counselling and testing among tuberculosis patients in south Ethiopia
BACKGROUND: To benefit from available care and treatment options, patients should first be counselled and tested for HIV. Our aim was to assess the acceptability of HIV testing among tuberculosis patients under routine care conditions in south Ethiopia.METHODS: We interviewed all adult tuberculosis patients who were treated at Arba Minch Hospital in Ethiopia between January and August 2005. After
Prevalence of diabetic retinopathy in relation to age at onset of the diabetes, treatment, duration and glycemic control
To study the frequency of diabetic retinopathy in relation to age at diagnosis, treatment, duration of diabetes and glycemic control as measured by means of HbA(1c) levels, we performed a cross-sectional, register-based study in the Helsingborg area of southern Sweden, comprising 2232 diabetic patients. Of the known diabetic population < 75 years old, approximately 70% were estimated to be include
Reduced capillary hydraulic conductivity in skeletal muscle and skin in Type I diabetes : a possible cause for reduced transcapillary fluid absorption during hypovolaemia
AIMS/HYPOTHESIS: Patients with Type I (insulin-dependent) diabetes mellitus have a reduced transcapillary fluid absorption from skeletal muscle and skin and thus defective plasma volume regulation during hypovolaemia. Our aim was to find whether a defective capillary filtration coefficient or impaired transcapillary driving force are aetiologic factors for this reduction.METHODS: We investigated 1
Investigation of effects of intake temperature on low load limitations of methanol partially premixed combustion
Methanol has unique properties as a fuel, and partially premixed combustion has promising results with high engine efficiency and low emissions. Low load studies with methanol partially premixed combustion are scarce, and the effect of intake temperature on low load methanol partially premixed combustion still remains an intriguing question. This study aims to investigate the effect of intake temp
What is the prospect of a perennial grain revolution of agriculture?
Non-technical summary:Agriculture has been dominated by annual plants, such as all cereals and oilseeds, since the very beginning of civilization over 10,000 years ago. Annual plants are planted and uprooted every year which results in severe disturbance of the soil and disrupts ecosystem services. Science has shown that it is possible to domesticate completely new perennial grain crops, i.e. plan
Superficial CD34-Positive Fibroblastic Tumor : A Clinicopathologic, Immunohistochemical, and Molecular Study of 59 Cases
Superficial CD34-positive fibroblastic tumor (SCD34FT) is a rare soft tissue neoplasm that shows overlapping features with PRDM10-rearranged soft tissue tumor (PRDM10-STT). This study characterizes the clinicopathologic, immunohistochemical, and molecular features of SCD34FT in a series of 59 cases. Fluorescence in situ hybridization to assess for PRDM10 rearrangement was performed in 12 tumors. I
Polypharmacy and adverse outcomes after hip fracture surgery
Background: We aimed to explore the effects of polypharmacy and specific drug classes on readmissions and mortality after hip surgery. Methods: We analyzed data on 272 consecutive hip fracture patients (72.1% females; age 82±9 years) who underwent acute hip replacement. We collected detailed data on the pharmacological treatment upon admission and discharge. Patients were followed up over a period
