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Evaluation of wild-type MIC distributions as a tool for determination of clinical breakpoints for Mycobacterium tuberculosis

Objectives: The aim of this study was to establish wild-type MIC distributions of first-line drugs for Mycobacterium tuberculosis, as well as to explore the usefulness of such distributions when setting clinical breakpoints. Methods: We determined the MICs of rifampicin, isonlazid and ethambutol for M. tuberculosis using a Middlebrook 7H10 dilution method for 90 consecutive clinical isolates, 8 re

Obesity and Surgical Treatment - A Cost-Effectiveness Assessment for Sweden

The rising trend in the prevalence of obesity has become a major public health concern in many countries during the past decades, partly because being obese is associated with comorbidities and death. The cost of treatment for obesity related diseases has become a heavy burden on the national health care budget in many countries. The treatment options for obesity are mainly weight management thera

Quality of life, physical function and MRI T2*in elderly low-risk MDS patients treated to a haemoglobin level of >= 120 g/L with darbepoetin alfa +/- filgrastim or erythrocyte transfusions

Objective: Anaemia in low-risk MDS is associated with reduced quality of life (QoL). Response to treatment with erythropoietin (EPO) + G-CSF is associated with improved QoL, but whether transfusion therapy with higher haemoglobin (Hb) target levels has similar effects is unknown. The objective for this prospective phase II Nordic multicentre trial was to assess QoL, response rate and physical func

Anskaffning av skriftliga bevis i skiljeförfarande - en effektivitetsanalys

Parternas tillgång till bevis i skiljeförfarande är ofta avgörande för tvistens utgång. I synnerhet är anskaffningen av skriftlig bevisning essentiell då den av skiljenämnden generellt tillmäts ett högre bevisvärde än övriga bevismedel. Det huvudsakliga syftet med uppsatsen är att undersöka om parter i ett skiljeförfarande som äger rum i Sverige kan anskaffa erforderlig bevisning utan att tidsåtgåThe parties’ access to evidence in arbitration is of major importance to the outcome of almost every dispute. The taking of documentary evidence is of particularly importance because of the high evidential value it is given by the arbitrators. The main purpose of the essay is to determine if the parties to arbitration in Sweden can gather adequate evidence without having to spend too much time and

Homework assignment and student achievement - Evidence from TIMSS 2019

Homework is widely used in most schools across the world to complement classroom teaching, increase knowledge retention, and foster good study habits. The research on the effect of homework assignment on student achievement is, however, inconclusive with earlier research indicating a positive relationship and newer studies giving a more nuanced picture. This thesis uses data from the 2019 wave of

Charlotte ling publications march 2018

1 1 List of publications - Charlotte Ling Total of 94 original publications, 16 invited review papers and 8 book chapters since 1999 H-index: 34; Number of citations ~6300 Original publications 1. Milana Kokosar, Anna Benrick, Alexander Perfilyev, Emma Nilsson, Thomas Källman, Claes Ohlsson, Charlotte Ling and Elisabet Stener-Victorin A Single Bout of Electroacupuncture Remodels Epigenetic and Tra

https://www.ludc.lu.se/sites/ludc.lu.se/files/charlotte_ling_publications_march_2018.pdf - 2026-05-16

A ground-validated NDVI dataset for monitoring vegetation dynamics and mapping phenology in Fennoscandia and the Kola peninsula

An NDVI dataset covering Fennoscandia and the Kola peninsula was created for vegetation and climate studies, using Moderate Resolution Imaging Spectroradiometer 16-day maximum value composite data from 2000 to 2005. To create the dataset, ( 1) the influence of the polar night and snow on the NDVI values was removed by replacing NDVI values in winter with a pixel- specific NDVI value representing t

An empirical ignition delay correlation allowing cetane number rating in a production compression ignition engine

This work presents an alternative cetane rating method using a production compression ignition (CI) engine, offering an accessible approach for preliminary fuel evaluation without the need for specialized equipment. As part of this work, an empirical correlation was developed linking ignition delay (ID) to both the cetane number (CN) and intake oxygen concentration. The test method follows the pri

Avdragsrätt i blandad verksamhet som inkluderar stadigvarande bostad- En analys av omsättningsmetoden och den svenska avdragsbegränsningen för stadigvarande bostad i ljuset av EU-rätten

Mervärdesskatten är ett av de mest harmoniserade områdena inom EU-rätten. En central del av mervärdesskattesystemet är rätten till avdrag för ingående mervärdesskatt. Många företag bedriver blandad verksamhet som innebär att en del verksamheten är mervärdesskattepliktig, medan en annan del inte är det. Fastighetsägare och bostadsrättsföreningar kan bedriva frivilligt beskattad uthyrning av lokalerValue Added Tax (VAT) is one of the most harmonized areas of EU law. A central element of the VAT system is the right to deduct input VAT. Mixed economic businesses include both VAT liable and VAT exempt activities. Landlords can have voluntary taxation of rental properties alongside permanent residences which are exempt from VAT. In such businesses, costs are often shared between the different ac

Ggm poster2013

Organizes a workshop on: Civil SoCiety, PolitiCS, and oPPoSition 09:45-10:00 Welcome by the Organizers Professor Diana Mulinari and Professor Helle Rydström Dept. of Gender Studies, Lund University 10:00-10:30 Lory Dance Visiting Professor, Center for Middle Eastern Studies, Lund University, and Senior Researcher, University of Nebraska, USA: “I See (Socially) Dead People”: Our Sixth Sense that Ha

https://www.genus.lu.se/sites/genus.lu.se/files/ggm_poster2013.pdf - 2026-05-16

Spatial trends of nitrate pollution and groundwater chemistry in Shimabara, Nagasaki, Japan

Groundwater contamination by nitrate is a common problem in many parts of the world. The agriculturally important Shimabara district in Nagasaki, Japan, is experiencing this problem. The general source of drinking water of the study area is groundwater and consequently the nitrate contamination is a significant problem. For this reason, a groundwater investigation was performed and water samples w

Immunohistochemical investigation of prognostic biomarkers in resected colorectal liver metastases : A systematic review and meta-analysis

Background: Many studies have investigated the prognostic role of biomarkers in colorectal liver metastases (CRLM). However, no biomarker has been established in routine clinical practice. The aim of this study was to scrutinize the current literature for biomarkers evaluated by immunohistochemistry as prognostic markers in patients with resected CRLM. Methods: A systematic review was performed ac

Automatic spin-entangled decays of heavy resonances in Monte Carlo simulations

We present a general method that allows one to decay narrow resonances in Les Houches Monte Carlo events in an efficient and accurate way. The procedure preserves both spin correlation and finite width effects to a very good accuracy, and is therefore particularly suited for the decay of resonances in production events generated at next-to-leading-order accuracy. The method is implemented as a gen

Improving the Developability of an Antigen Binding Fragment by Aspartate Substitutions

Aggregation can be a major challenge in the development of antibody-based pharmaceuticals as it can compromise the quality of the product during bioprocessing, formulation, and drug administration. To avoid aggregation, developability assessment is often run in parallel with functional optimization in the early screening phases to flag and deselect problematic molecules. As developability assessme

Differential inhibitory effect on human nociceptive skin senses induced by local stimulation of thin cutaneous fibers

It is known that stimulation of thin cutaneous nerve fibers can induce long lasting analgesia through both supraspinal and segmental mechanisms, the latter often exhibiting restricted receptive fields. On this basis, we recently developed a new method, termed cutaneous field stimulation (CFS), for localized stimulation of A delta and C fibers in the superficial part of the skin. In the present stu