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This paper presents a joint experimental and large eddy simulation (LES) study of lean premixed low swirl stabilized methane/air flames at different Reynolds numbers (Re similar to 20,000-100,000). The aims are to investigate the sensitivity of the structures and dynamics of low swirl flames to the inflow boundary conditions and to evaluate the capability of an LES flamelet model in predicting the
Cholestasis is a frequent clinical syndrome, which is caused by a dysfunction in bile formation of the hepatocyte or from obstruction of the biliary tract. This is associated with inflammation of the liver tissue, resulting in severe liver injury. In this inflammatory process, leukocyte recruitment has emerged as a key feature. Therefore, the aim of this thesis was to analyze the detailed mechanis
We present a catalog of high-energy gamma-ray sources detected by the Large Area Telescope (LAT), the primary science instrument on the Fermi Gamma-ray Space Telescope (Fermi), during the first 11 months of the science phase of the mission, which began on 2008 August 4. The First Fermi-LAT catalog (1FGL) contains 1451 sources detected and characterized in the 100 MeV to 100 GeV range. Source detec
In high-energy heavy-ion collisions, the correlations between the emitted particles can be used as a probe to gain insight into the charge creation mechanisms. In this Letter, we report the first results of such studies using the electric charge balance function in the relative pseudorapidity (Delta eta) and azimuthal angle (Delta phi) in Pb-Pb collisions at root s(NN) = 2.76 TeV with the ALICE de
Purpose To explore the effect of high-dose ifosfamide in first-line treatment for patients <= 40 years of age with nonmetastatic osteosarcoma of the extremity. Patients and Methods From March 1997 to September 2000, 182 patients were evaluated. Primary treatment consisted of two blocks of high-dose ifosfamide (15 g/m(2)), methotrexate (12 g/m(2)), cisplatin (120 mg/m(2)), and doxorubicin (75 mg/m(
China uses half the world’s annual coal consumption, since coal is the primary energy source for heating in urban areas, particularly in northern China. This entails significant challenges for urban air quality in China and for the global climate. Unlike the electricity and transportation sectors, the heating sector has received little attention from policy and research actors in China, despite ve
NMR-spectroscopy enables unique experimental studies on protein dynamics at atomic resolution. In order to obtain a full atom view on protein dynamics, and to study specific local processes like ring-flips, proton-transfer, or tautomerization, one has to perform studies on amino-acid side chains. A key requirement for these studies is site-selective labeling with 13C and/or 1H, which is achieved i
OBJECTIVE:: This study investigates the hypoperfusion effects of epinephrine in local anesthesia in eyelid surgery. A novel form of extended-wavelength diffuse reflectance spectroscopy was evaluated. METHODS:: Blood perfusion in porcine eyelid flaps was measured using laser Doppler velocimetry and laser speckle contrast imaging, whereas the tissue response was measured using diffuse reflectance sp
Polyelectrolyte adsorption and polymer mediated interactions in different colloidal polymer systems have been studied in this work. Theoretical methods and experimental techniques are combined, in order to obtain more general reliable results, as well as a deep understanding of the molecular mechanisms that are responsible for the observed behaviors. Two different types of highly charged cationic
Directed differentiation of human induced pluripotent stem cells (iPSCs) into retinal pigmented epithelium (RPE) holds great promise in cell replacement therapy for patients suffering from degenerative eye diseases, including age-related macular degeneration (AMD). In this study, we generated iPSCs from human dermal fibroblasts (HDFs) by electroporation with episomal plasmid vectors encoding OCT4,
Aims This study examines the association between the incidence of drug abuse (DA) and linking (communal) social capital, a theoretical concept describing the amount of trust between individuals and societal institutions. Methods We present results from an 8-year population-based cohort study that followed all residents in Sweden, aged 15–44, from 2003 through 2010, for a total of 1,700,896 men and
BACKGROUND: Ulcerative colitis and Crohn's disease are the major chronic inflammatory bowel diseases affecting the gastrointestinal tract in humans. Imaging techniques such as endoscopy and computed tomography are used to monitor disease activity. Magnetic resonance imaging (MRI) is emerging as a diagnostic modality, and studies have shown that MRI can be used in the diagnostic procedure of patien
Syftet med den här uppsatsen är att undersöka hur aprilskämt i SVT har förändrats mellan 1997 och 2019 och identifiera anledningar till varför förändringar har skett. Analysen är således uppdelad i två avdelningar. I den första avdelningen görs en innehållsanalys med hjälp av Entmans gestaltningsmetod, på fem utvalda aprilskämt som har sänts av lokalredaktioner på SVT. Analysen utgår ifrån Harcup The purpose of this thesis is to investigate how April Fools' Day pranks on SVT (Swedish public service television) have evolved between 1997 and 2019 and to identify the reasons behind these changes, with a central focus on the concept of national identity. The analysis is thus divided into two sections. In the first section, a content analysis is conducted using Entman's framing method o
Climate change is affecting all regions of the globe, causing a shift of temperature distributions. As species try to track their optimal thermal conditions, they are also potentially met with new photic environments. Photoperiod is the main cue for synchronizing migratory birds' circannual rhythms, affecting both their physiology and migration. Thus, their ability to incorporate and adjust to
Dagens textilindustri är starkt präglad av fast fashion, en global industri som bygger på stora inköp och små marginaler vilket leder till en överproduktion där 40 procent av de textilier som tillverkas globalt aldrig kommer ut på marknaden. Detta resulterar i bristande arbets- och levnadsförhållanden i produktionsländer samt enorma utsläpp. Med hjälp av politiska incitament och teknologiska framsToday's textile industry is strongly characterized by fast fashion, a global industry based on large purchases and small margins, leading to overproduction where 4 percent of the textiles produced globally never reach the market. This results in poor working and living conditions in producing countries and huge emissions. With policy incentives and technological advances, we can move towards l
Accelerator programs that support enterprises in their early stages are growing in numbers, acknowledged by many as an important organizational form for achieving economic growth. However, focusing solely on economic growth has proven to be detrimental for the environment and not enough to solve the challenges of our current social systems. As a response, accelerators and social enterprises that f
The understanding of the link between the water, sanitation and hygiene (WASH) sector and gender has been extensively researched and is widely accepted as foundational for achieving safe and equal provision of WASH-facilities. Interventions aimed at improvements in the sector are common in low- and middle-income countries, however, there is a limited number of approaches for measuring their outcom
Introduction: Warfarin treatment with a high time in therapeutic range (TTR) is correlated to fewer complications. The TTR in Sweden is generally high but varies partly depending on local expertise and traditions. A dosing algorithm could minimize variations and increase treatment quality. Here we evaluate the performance of a computerized dosing algorithm. Materials and methods: 53.779 warfarin t
Kollektivtrafiken spelar en central roll i ett hållbart transportsystem, särskilt när det gäller att uppnå globala hållbarhetsmål och nationella transportpolitiska mål. I täta stadsmiljöer leder begränsat gatutrymme till konkurrens mellan olika transportmedel, såsom mellan cykelbanor, gatuparkering och dedikerad bussinfrastruktur. En viktig faktor som påverkar bussars framkomlighet är körfältsbredPublic transport plays a key role in creating sustainable urban transport systems, particularly in meeting global sustainability targets and national transport policy goals. In dense urban environments limited street space leads to competition between different modes of transport such as between cycle lanes, on-street parking, and dedicated bus infrastructure. One important factor affecting bus ma
PURPOSE: To determine whether Comprehensive Geriatric Assessment (CGA)-based healthcare, delivered by a mobile team over 24 months in patients' homes reduces hospital care or improves quality of life, physical performance, frailty, activities of daily living (ADL), or cognition and whether it reduces mortality or number of hospital admissions.METHODS: Patients ≥ 75 years of age, with ≥ 3 visits to
