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Background: Periodontitis and oral pathogenic bacteria can contribute to the development of rheumatoid arthritis (RA). A connection between serum antibodies to Porphyromonas gingivalis (P. gingivalis) and RA has been established, but data on saliva antibodies to P. gingivalis in RA are lacking. We evaluated antibodies to P. gingivalis in serum and saliva in two Swedish RA studies as well as their
Using new high-resolution data of CO (2-1), H and H obtained with the Northern Extended Millimeter Array (NOEMA) and the Multi-Unit Spectroscopic Explorer (MUSE) at the Very Large Telescope, we have performed a Toomre Q disc stability analysis and studied star formation, gas depletion times and other environmental parameters on sub-kpc scales within the z ∼0 galaxy SDSS J125013.84+073444.5 (LARS 8
Popular Abstract in Swedish För att en multicellulär organism som männinskan ska kunna fungera måste celldelningen strikt kontrolleras. Protein som reglerar celldelning på cellulär nivå kallas för "tillväxtfaktorer". Vi har studerat ett sådant protein som kallas för transforming growth factor-beta (TGF-b). Namnet TGF-b kommer sig utav att detta protein kan transformera (omvandla) epiteliala njurceTransforming growth factor-beta (TGF-b) is a well-characterised growth regulatory factor, which acts on most cell types. This thesis has focused on the regulatory roles of TGF-b on normal lymphocytes. One interesting finding is that TGF-b acts both costimulatory and inhibitory on T-lymphocytes. The costimulatory effect depends on the presence of monocytes and is mediated by these cells. Furthermor
Design is an activity aimed at solving an unsolved problem or improving an existing solution. In the area of societal safety, there are many activities that could be classified as design activities. For example when different actors are implementing measures to mitigate certain risk scenarios or when they are considering actions that could improve their capability to respond to various crises. We
Introduction: Warfarin treatment with a high time in therapeutic range (TTR) is correlated to fewer complications. The TTR in Sweden is generally high but varies partly depending on local expertise and traditions. A dosing algorithm could minimize variations and increase treatment quality. Here we evaluate the performance of a computerized dosing algorithm. Materials and methods: 53.779 warfarin t
Conservation priority areas and programs are often established without consideration of future changes in species distributions. However, global change is expected to threaten the persistence of several species while offering opportunities for range expansion to others. In this study, building on previous work, we develop and implement an approach to classify bird species according to their degree
Quantitative assessment of regional myocardial function at rest and during stress with Doppler tissue imaging (DTI) plays an important role in daily routine echocardiography. However, reliable visual analysis is largely dependent on image quality and adequate border delineation, which still remains a challenge in a significant number of patients. In this respect, an ultrasound contrast agent (UCA)
Aim: This paper describes the quality assurance (QA) work performed in the Swedish multicenter ARTSCAN (Accelerated RadioTherapy of Squamous cell CArcinomas in the head and Neck) trial to guarantee high quality in a multicenter study which involved modern radiotherapy such as 3DCRT or IMRT. Materials and methods: The study was closed in June 2006 with 750 randomised patients. Radiation therapy-rel
Popular Abstract in Swedish Låg temperatur begränsar i stor utsträckning överlevnad och expansion av vegetation. Under senare år har samverkan mellan låg temperatur och hög instrålning, som leder till försämrad fotosynteseffektivitet, rönt stor uppmärksamhet. I denna avhandling tillämpas nya metoder för att relatera rumsliga variationer i temperatur och instrålning till fotosynteseffektivitet ochLow temperature has a large impact on the survival and distribution of plants. Interactive effects with high irradiance lead to cold-induced photoinhibition, which may impact on the establishment and growth of tree seedlings. In this thesis, novel approaches are applied for relating the spatial variability in low temperature and irradiance to photosynthetic performance and growth of tree seedlings
One feature of climate change is the increasing heat exposure in many workplaces where efficient cooling systems cannot be applied. Excessive heat exposure is a particular problem for working people because of the internal heat production when muscle work is carried out. The physiological basis for severe heat stroke, other clinical effects, and heat exhaustion is well known. One feature of this h
The separation of abiotic and biotic factors affecting populations and communities is an important step in understanding how climate change can influence ecological processes, but quantifying their relative contribution to community changes is a challenge. We assessed the effect of temperature and species interactions on the population dynamics of a forest bird community with a hierarchical dynami
Purpose To explore the effect of high-dose ifosfamide in first-line treatment for patients <= 40 years of age with nonmetastatic osteosarcoma of the extremity. Patients and Methods From March 1997 to September 2000, 182 patients were evaluated. Primary treatment consisted of two blocks of high-dose ifosfamide (15 g/m(2)), methotrexate (12 g/m(2)), cisplatin (120 mg/m(2)), and doxorubicin (75 mg/m(
Popular Abstract in Swedish Denna studie är inriktad på förhållandet mellan människa och hav på Tongaöarna i Polynesien. Särskild tonvikt läggs på det samlande av alger och ryggradslösa djur som utförs av kvinnorna i lagunerna och på korallreven. Beskrivningar ges av hur dessa organismer anskaffas och hur de används för olika ändamål, den plats de haft i religiösa föreställningar samt hur folkökniThis monograph analyses marine gathering in the Polynesian Kingdom of Tonga from ecological, social and cognitive perspectives. The overarching issues explored are (1) the significance of marine gathering in the past and present, (2) how seaweeds and marine invertebrates have been perceived, classified, named and used, (3) how they have been implicated in social relations, and (4) how the integrat
This conference volume is structured by the five research areas of the Lund syna-gogue project “The Ancient Synagogue: Birthplace of Two World Religions,” funded by The Bank of Sweden Tercentenary Foundations, and by its time limit up to ca 200 C.E. The aim of the conference was to give an opportunity for young, emerging scholars to interact with some of the most prominent and established scholars
Climate change is affecting all regions of the globe, causing a shift of temperature distributions. As species try to track their optimal thermal conditions, they are also potentially met with new photic environments. Photoperiod is the main cue for synchronizing migratory birds' circannual rhythms, affecting both their physiology and migration. Thus, their ability to incorporate and adjust to
Dagens textilindustri är starkt präglad av fast fashion, en global industri som bygger på stora inköp och små marginaler vilket leder till en överproduktion där 40 procent av de textilier som tillverkas globalt aldrig kommer ut på marknaden. Detta resulterar i bristande arbets- och levnadsförhållanden i produktionsländer samt enorma utsläpp. Med hjälp av politiska incitament och teknologiska framsToday's textile industry is strongly characterized by fast fashion, a global industry based on large purchases and small margins, leading to overproduction where 4 percent of the textiles produced globally never reach the market. This results in poor working and living conditions in producing countries and huge emissions. With policy incentives and technological advances, we can move towards l
Corporate Social Responsibility (CSR) has emerged to cover the company’s responsibility in their participation in solving social problems. Research has shown that CSR planning and implementation vary significantly between developed and developing countries. Previous literature on CSR were mainly dominated by Western nuances, and they overlooked the implication of socio-cultural aspects in the deve
The aim of this paper was to analyse how stakeholders such as municipalities and tourism operators at small-scale destinations strategically work to handle issues regarding carrying capacity in order to protect the social sustainability. The paper examines the world heritage site Cinque Terre in Italy, which has experienced a major change in tourist flows during the last decade. The comprising fiv
Mussels, like other intertidal organisms, depend on the motion of water throughout their entire life cycle. Hydrodynamic forces are essential for the transportation and settlement of mussel larvae, as well as feeding and growth for adult mussels. In this study physical factors, such as local water velocities and wave characteristics, were measured over an eight-week period in Port Alfred Marina, o
Intresset för historia har funnits med mig redan i tidig ålder vilket under åren resulterat i många utflykter till museer och historiskt viktiga platser. Eftersom jag växte upp i Simrishamn, där rika lämningar från såväl brons- som järnålder finns, hade jag under min uppväxt aldrig långt till närmsta utflyktsmål. De kanske mest intressanta, och för bygden speciella, är de hällristningar som finns Ever since I was a child I have had a historical interest, which has resulted in many excursions to museums and sites of historical significance. Since I grew up in the town of Simrishamn, where important historical traces from both the bronze and Iron Age are visible, I never had far to the closest excursion site. The most interesting and of greatest importance to the region being the rock carvin
