Filtyp
Objective: To conduct a cost-effectiveness study of nasal budesonide versus surgical treatment in the management of nasal polyps. Design and methods: A decision-tree model reflecting two different treatment strategies for nasal polyps in Sweden was developed. The first strategy was initial polypectomy, performed under three different sets of circumstances: inpatient functional endoscopic surgery,
Aim To identify clinical, immunological and biochemical factors that predict remission, and its duration in a large cohort of young adults with Type 1 diabetes mellitus (DM). Methods In Sweden 362 patients (15-34 years) classified as Type 1 DM were,, included in a prospective, nation-wide population-based study. All patients were followed at local hospitals for examination of HbA(1c) and insulin d
Background: Official guidelines that promote evidence-based and cost-effective prescribing are of main relevance for obvious reasons. However, to what extent these guidelines are followed and their conditioning factors at different levels of the health care system are still insufficiently known. In January 2004, a decentralized drug budget was implemented in the county of Scania, Sweden. Focusing
Background The study was designed to evaluate the analgesic effect and possible adverse effects of acupuncture for pelvic and low-back pain during the last trimester of pregnancy. Methods Following individual informed consent, 72 pregnant women reporting pelvic or low-back pain were randomized during pregnancy weeks 24-37 to an acupuncture group (n = 37) or to a control group (n = 35) at three mat
Syftet med detta arbete är att utreda om brandmännens praktiska färdigheter har förändrats sedan utbildningen Skydd Mot Olyckor (SMO) trädde i kraft. I detta arbete förklaras praktiska färdigheter som ”hur väl man hanterar och är insatt i hur verktyg och redskap fungerar som ingår i brandmannayrket – t.ex. kedjesåg, klippverktyg, pumpar, motorkap med mera”. Vid Helsingborgs Brandförsvar där studieThe purpose of this study is to investigate if the practical skills of firemen have changed since the education Skydd Mot Olyckor, SMO (eng. Protection Against Accidents, SMO) was introduced. In this study, the term ”practical skills” is defined as ”how competently one handles and understands the use and function of tools used in the fireman profession, e.g. chainsaw, cutting tools, pumps and cros
New Public Management in practice. A study of employers´strategies in wage policy settings in a minicipality. The purpose of this study was to contribute to a better understanding of the implementation of wage policies and pay criteria's in a municipality from the perspective of the employers. The study is thus an attempt to analyse how employers in a municipality, in southern Sweden, impleme
Populärvetenskaplig sammanfattning Fenologi innebär studier av naturligt återkommande händelser som till exempel bladsprickning, knoppbristning och vissningen av blad. Det är viktigt att förstå hur klimatförändringen påverkar tidpunkten då dessa händelser sker eftersom det i sin tur påverkar kol-, närings- och den hydrologiska cykeln. Fältobservationer har varit den mest använda metoden för att saPhenology is the study of the timing of natural events such as leaf-out, bud burst and senescence relative to climate change. It is important to understand how the climate change will affect the timing of these events as it in turn affects the carbon-, nutrient- and the hydrological cycles. Field observations is the most common way to gather phenology data but the result is dependent on the skill
Växters fenologiska händelser påverkas av klimatet och tid för knoppsprickning hos träd kan därför användas som indikator på klimatförändringen. Enligt forskning kommer temperaturen med största sannolikhet att öka i framtiden och med det följer att växters knoppsprickning förväntas ske tidigare. I denna studie har tidpunkten för knoppsprickningen för hägg, björk och asp i Skåne simulerats med hjälPlants phenological events are influenced by the climate and the timing of budburst of trees is therefore an excellent indicator for climate change. According to research, temperature will most likely increase in future and with that follows an earlier budburst. In this study, budburst were simulated for bird cherry, birch and aspen in Skåne, in the southern part of Sweden, with two phonological m
Populärvetenskaplig sammanfattning Vad har berget i Romeleåsen varit med om? Jordskorpan är uppbyggd av ett antal plattor. Vid plattgränser under oceanerna bildas ny skorpa av magma som tränger upp. Oceanplattan kan inte öka i storlek. Där oceanplattan möter en platta med kontinental jordskorpa tränger oceanplattan under kontinentalplattan (subduktion, t. ex. Anderna). Vid kollisionen dras sedimeRomeleåsen is the south-westernmost exposure of the Fennoscandian Shield in Sweden. Fennoscandia forms a part of the East European Craton and was extended to the south-west during prolonged episodes of accretion during the period 1.95-1.55 Ga. Metamorphic reworking took at least place during the Hallandian/Danopolonian orogeny at 1.47-1.38 Ga and during the Sveconorwegian orogeny 1.10-0.92 Ga. Hig
This research proposes that an interdisciplinary approach to understanding the concept of culture and culture change could be beneficial for Sustainable Development. It explores the transferability of the DIKT Learning Model and theory of Creative Populations, originally found in management literature, and applies them to a social change corporation in Medellin, Colombia. The corporation analyzed
A multitude of biogeochemical feedback mechanisms govern the climate sensitivity of Earth in response to radiation balance perturbations. One feedback mechanism, which remained missing from most current Earth System Models applied to predict future climate change in IPCC AR6, is the impact of higher temperatures on the emissions of biogenic volatile organic compounds (BVOCs), and their subsequent
Many environmental risk factors for hepatobiliary cancers are known but whether they are associated with specific cancer types is unclear. We present here a novel approach of assessing standardized incidence ratios (SIRs) of previously diagnosed comorbidities for hepatocellular carcinoma (HCC), gallbladder cancer (GBC), cholangiocarcinoma (CCA) and ampullary cancer. The 13 comorbidities included a
Complementary and alternative medicine (CAM) is used as a complementary intervention in psychiatric healthcare. The reasons for using or not using CAM in psychiatric care in Sweden, and how such decisions are taken, are largely unknown. The aim was to investigate arguments for and against the use of CAM in Swedish psychiatric care, and how decisions are made. Interviews with 10 persons in decision
Background: Chronic or recurrent rhinosinusitis without polyps (CRSsNP) is characterized by a persistent inflammation of the sinonasal mucosa. The underlying cause is unclear but increasing interest has been directed toward changes in the sinonasal microbiome as a potential driver. Methods: Twenty-two patients diagnosed with CRSsNP were treated with antibiotics for 13 days, followed by 5 consecuti
Cholangiocarcinoma (CCA) is a type of liver cancer with an aggressive phenotype and dismal outcome in patients. The metastasis of CCA cancer cells to distant organs, commonly lung and lymph nodes, drastically reduces overall survival. However, mechanistic insight how CCA invades these metastatic sites is still lacking. This is partly because currently available models fail to mimic the complexity
Background/aims: Congestion is prognostically relevant in cardiac transthyretin amyloidosis (ATTR-CA), but whether congestion has an incremental prognostic value beyond the well-established, congestion-sensitive NT-proBNP is unknown. Therefore, we aimed to comparatively evaluate the prognostic utility of several congestion surrogates over NT-proBNP. Methods: We estimated hazard ratios by Cox propo
In a time marked by growing environmental and societal challenges, where multiple planetary boundaries are being crossed, the way we conduct business practices needs to be rethought. Regenerative business models offer a path towards a more responsible future by incorporating strategies that go beyond net zero and focus on actively restoring the natural and social systems they operate in, creating
Streptococcus pneumoniae is a bacterium of great global importance, responsible for more than one million deaths per year. This bacterium is commonly acquired in the first years of life and colonizes the upper respiratory tract asymptomatically by forming biofilms that persist for extended times in the nasopharynx. However, under conditions that alter the bacterial environment, such as viral infec
Background: Lifestyle choices, metformin, and dietary supplements may prevent GDM, but the effect of intervention characteristics has not been identified. This review evaluated intervention characteristics to inform the implementation of GDM prevention interventions. Methods: Ovid, MEDLINE/PubMed, and EMBASE databases were searched. The Template for Intervention Description and Replication (TIDieR
Background: The tumoricidal complex alpha1-oleate targets bladder cancer cells, triggering rapid, apoptosis-like tumor cell death. Clinical effects of alpha1-oleate were recently observed in patients with non-muscle invasive bladder cancer (NMIBC), using a randomized, placebo-controlled study protocol. Aims: To investigate if there are dose-dependent effects of alpha1-oleate. Materials and Methods
