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Background: Rectal washout (RW) is routinely performed during anterior resection (AR) for rectal cancer to reduce local recurrence (LR), although is sometimes not performed during minimally invasive surgery (MIS) procedures due to technical challenges and time consumption. The aim was to investigate the impact of RW on the oncological outcome after AR for rectal cancer in a registry cohort. Method
The severity of urinary tract infection (UTI) reflects the quality and magnitude of the host response. While strong local and systemic innate immune activation occurs in patients with acute pyelonephritis, the response to asymptomatic bacteriuria (ABU) is low. The immune response repertoire in ABU has not been characterized, due to the inherent problem to distinguish bacterial differences from hos
Nations around the world are feverishly developing new standards relating to Building Information Modelling (BIM) in the construction industry which may enable teams to leverage greater value from BIM implementation and model authorship efforts. This study reflects on ongoing standardisation initiatives in Sweden and considers where current research efforts fit in. There is limited research presen
BACKGROUND: Treatment of diabetic foot ulcers includes a number of different regimes such as glycaemic control, re-vascularization, surgical, local wound treatment, offloading and other non-surgical treatments. Although considered the standard of care, the scientific evidence behind the various debridements used is scarce. This presentation will focus on debridement and V.A.C. Therapy, two treatme
Contaminated drinking water (DW) is a major source of exposure to per- and polyfluoroalkyl substances (PFAS) at locations around PFAS production/use facilities and military airports. This study aimed to investigate quantitative relationships between concentrations in DW and serum of nine perfluoroalkyl acids (PFAAs) in Swedish adult populations living near contamination hotspots. Short-chained (PF
Radionuclides released and discharged into the environment from nuclear and other radiation-related facilities, such as the European Spallation Source (ESS), may accumulate in aquatic bottom sediments. Sediments should therefore, as recommended by the IAEA, be monitored regularly. This report describes the setting up of a methodology for zero-point assessments of the radiation levels in sediments
Four-wave mixing techniques, such as coherent anti-Stokes Raman spectroscopy (CARS), laser-induced grating spectroscopy (LIGS), and degenerate four-wave mixing (DFWM), have been widely used in combustion diagnostics due to their advantages of high signal-to-noise ratio (S/N), coherent signal, and spatial resolution. In this work, a nano-second pulsed laser is utilized to generate mid-infrared (nea
Context. Transmission spectroscopy is one of the most powerful techniques used to characterize transiting exoplanets, since it allows for the abundance of the atomic and molecular species in the planetary atmosphere to be measured. However, stellar lines may bias the determination of such abundances if their center-To-limb variations (CLVs) are not properly accounted for. Aims. This paper aims to
Accepted manuscripts are peer-reviewed but have not been through the copyediting, formatting, or proofreading process. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly at
https://www.regenerative-neurobiology.lu.se/sites/regenerative-neurobiology.lu.se/files/eneuro.0106-15.2015.pdf - 2026-07-09
Species distribution models (SDM) have been used to estimate potential geographic distributions of hundreds of species and plant communities. Nonetheless, very few studies have been conducted which attempted to model the distributions of mangrove species in future under climate change scenarios and under different sea surface salinity at a local level. The present study used a machine learning bas
China is now undergoing a fast process of industrialization, with the industry sector playing an important role in the overall economy. Among the many economic areas in China, Yangtze River Delta (YRD) takes the lead. The macro economy development and energy use status quo of both China and YRD are depicted, the past and current situation of air pollution and GHGs emissions is presented, and detai
Rationale, Aims and Objectives: Colonoscopy, though common, can be uncomfortable, necessitating routine assessment of patient experience per European guidelines. Positive patient experiences are crucial as they influence willingness for repeat procedures. Patient-reported experience measures (PREMs) effectively capture patient perspectives through surveys, empowering patients to influence healthca
BACKGROUND: As the global population ages, the demand for palliative care is expected to increase. However, studies show that older patients often receive inadequate palliative care, partly due to healthcare professionals lacking sufficient training and tools to identify and address palliative care needs effectively. This study aims to explore healthcare professionals' experiences regarding facili
Background: We set out to profile the immune mechanisms active in treatment-naïve oligoarticular JIA (oJIA) to improve the knowledge of its immunopathogenesis, to identify potential biomarkers that can aid diagnosis, predictions and that correlate with clinical disease parameters. Methods: Using Olink proteomics (inflammation panel measuring 92 markers), we defined and compared the inflammation pr
The aim of this study is to assess the content of heavy metals and their potential health risk in consumed food crops. To this end, the samples from vegetables, rice, potato, onion, and black tea were derived from high sales and commonly consumed types. The noncarcinogenic health risk of heavy metals to the adults, teens, and children was estimated by target hazard quotients (THQs) and hazard inde
Aims: Reirradiation is becoming more frequently used in paediatric tumours of the central nervous system (CNS). To fill the void of clinical guidelines, the Swedish Working Group of Paediatric Radiotherapy compiled consensus guidelines on reirradiation in 2019. The aim of this study was to evaluate the outcome of children reirradiated for CNS tumours since implementing the guidelines. Material and
Background: Behavioural variant Frontotemporal Dementia (bvFTD) is an early-onset dementia characterised by early anterior cingulate (AC) neuropathological insult. The AC exhibits high morphological heterogeneity, which may be classified according to the presence of a paracingulate sulcus (PCS), a tertiary sulcus that, when present, develops during the third gestational trimester and thereafter re
BACKGROUND: Leukocytes have been reported to have tumor stimulating effects in colorectal cancer, among other malignancies. In line with this, earlier research has shown improved disease-free survival in patients with postoperative neutropenia compared to non-neutropenic patients following cytoreductive surgery (CRS) and hypertherm intraperitoneal chemotherapy (HIPEC).AIM: To evaluate the impact o
This dissertation discusses various issues relating to Iron Age settlements in the area around the central place of Uppåkra. Most of the sites have been excavated by contract archaeology. The discussion begins with a presentation of the material from the houses in the settlements, detailing the different construction types and discussing the functions and chronological aspects of the houses. The d
PURPOSE: The local immune infiltrate's influence on tumor progression may be closely linked to tumor-intrinsic factors. The study aimed to investigate whether integrating immunologic and tumor-intrinsic factors can identify patients from a low-risk cohort who may be candidates for radiotherapy (RT) de-escalation.EXPERIMENTAL DESIGN: The SweBCG91RT trial included 1,178 patients with stage I to IIA
