Filtyp
Forest plantations play a crucial role in the livelihoods of Rwandan people. They provide valuable wood resources, such as timber and biomass energy. The first plantations created in the colonial period from 1920 to 1948 contained only exotic Eucalyptus species, which is thought to out-perform native species in terms of more rapid wood production. Over time, this resulted in the domination of non-
In the face of growing criticism of traditional climate adaptation financing mechanisms that often reproduce technocratic approaches and risk entrenching inequalities, this research explores how climate justice, gender equity, and locally-led adaptation can be integrated into adaptation finance in subnational contexts. Analysing case studies from the coastal cities of Cartagena and Buenaventura, i
Global exploration and production of minerals is increasingly located in areas populated by indigenous people. Conflicts that arise between multinational corporations and local activists and/or indigenous people are widespread while the understanding of such issues are still lacking. The Swedish government encouraging an expanding mining industry have caused great resistance, particularly due to t
Photodynamic therapy (PDT) is an established treatment for actinic keratosis and selected non-melanoma skin cancers. Still, its broader use is limited by pain, skin irritation, and formulation constraints associated with high photosensitiser concentrations. This study aimed to develop and evaluate a Crystalip®-based topical PDT formulation that enables two-step manufacturing, delivers methyl-amino
This thesis focuses on the issue of abortion rights in the Philippines, a country which maintains one of the strictest abortion laws globally, prohibiting abortion under all circumstances without exceptions. Despite severe penalties, unsafe abortions remain widespread, resulting in approximately 1.1 million induced abortions and around 1,000 maternal deaths annually. The interaction between the Ph
This thesis looks at climate change adaptation strategies in the Inner Forth region in Scotland. The region is expected to suffer from climate change induced stresses such as flooding, sea level rise and storm surges. To cope with these changes, a new coastal adaptation strategy has been suggested, based on soft solutions such as wetland creation and managed realignment. This has caused a dispute,
Background: Prostate-specific membrane antigen (PSMA) radiotracers such as [18F]PSMA-1007 used with positron emission tomography-computed tomography (PET-CT) is promising for initial staging and detection of recurrent disease in prostate cancer patients. The block-sequential regularization expectation maximization algorithm (BSREM) is a new PET reconstruction algorithm, which provides higher image
The present-day ocean-climate system configuration took shape during the Miocene Epoch. Toward the end of the epoch, in the late Tortonian at ca. 8.5 Ma, there was an exceptional event: collisional disruption of an >150-km-diameter asteroid, which created the Veritas family of asteroids in the asteroid belt. This event increased the flux of interplanetary dust particles rich in 3He to Earth and pr
Objective/background: Mycotic aortic aneurysms are rare, life threatening, and complex. This nationwide study aimed to assess outcome after repair of mycotic thoracic aortic aneurysms (MTAAs). Methods: Patients treated in Sweden for MTAAs between 2000 and 2016 were identified in the Swedish vascular registry (2010–16) and local patient registries (2000–09). Primary outcome was survival, and second
Long-term stability of endosseous implants depends on successful bone formation, ingrowth and adaptation to the implant. Specifically, it will define the mechanical properties of the newly formed bone-implant interface. 3D imaging during mechanical loading tests (in situ loading) can improve the understanding of the local processes leading to bone damage and failure. In this study, titanium screws
Background: Recently, the block-sequential regularized expectation maximization (BSREM) reconstruction algorithm was commercially introduced (Q.Clear, GE Healthcare, Milwaukee, WI, USA). However, the combination of noise-penalizing factor (β), acquisition time, and administered activity for optimal image quality has not been established for
Water scarcity is a consequence of complex interactions between water access and water use. In fact, the time period over which precipitation deficit accumulates is a determing factor for the occurrence of drought. Drought induces crop production losses and far-reaching societal effects. In the South American Altiplano, drought is a major hazard. Here, drought leads to food shortages, malnutrition
Background: Central nervous system tumours constitute 25% of all childhood cancers; more than half are located in the posterior fossa and surgery is usually part of therapy. One of the most disabling late effects of posterior fossa tumour surgery is the cerebellar mutism syndrome (CMS) which has been reported in up to 39% of the patients but the exact incidence is uncertain since milder cases may
OBJECTIVE: To examine the predictive capability of a 1-h vs 2-h postload glucose value for cardiovascular morbidity and mortality.DESIGN: Prospective, population-based cohort study (Malmö Preventive Project) with subject inclusion 1974-1992.RESULTS: Median age was 48 (25th-75th percentile: 48-49) years and mean FBG 4.6 ± 0.6 mmol/L. FBG and 2-h postload BG did not independently predict cardiovascu
Comprehensive experimental data on the fatigue properties of extruded Al6082-T6 is used together with crystal plasticity simulations to investigate the microstructure and surface roughness influence on fatigue initiation. Thesurface roughness of the specimens used in the experiments was mapped with White Light Interferometry (WLI) and the location of the fatigue initiation sites was identified and
OBJECTIVES: There is highly suggestive evidence for an effect of air pollution exposure on dementia-related outcomes, but evidence is not yet present to clearly pinpoint which pollutants are the probable causal agents. The aims of this study was to assess the longitudinal association between exposures of fine ambient particulate matter (PM2.5) from residential wood burning, and vehicle exhaust, wi
OBJECTIVE: This study examined the prevalence and correlates of physical violence and rape among female sex workers (FSWs) in Ethiopia.DESIGN: A cross-sectional study using respondent-driven sampling technique.SETTING: Eleven major towns in Ethiopia.PARTICIPANTS: 4900 FSWs.MAIN OUTCOME MEASURES: The prevalence of experiences of physical beating and rape.RESULTS: Among FSWs, 17.5% reported physical
Background: Steroid injections are used in idiopathic carpal tunnel syndrome (CTS), but evidence of efficacy beyond 1 month is lacking. Objective: To assess the efficacy of local methylprednisolone injections in CTS. Design: Randomized, placebo-controlled trial. (ClinicalTrials.gov: NCT00806871) Setting: Regional referral orthopedic department in Sweden. Patients: Patients aged 18 to 70 years with
Introduction: CAM2038 q1w (once weekly) and q4w (once monthly) are investigational buprenorphine subcutaneous (SC) formulations based on FluidCrystal® injection depot technology. These two drug products are being developed for opioid dependence treatment, with a target for once-weekly and once-monthly SC dosing. The rationale for developing two products with different dosing frequencies is that tr
AIMS/HYPOTHESIS: Type 2 diabetes is a chronic metabolic disorder associated with devastating microvascular complications. Genome-wide association studies have identified more than 60 genetic variants associated with type 2 diabetes and/or glucose and insulin traits, but their role in the progression of diabetes is not established. The aim of this study was to explore whether these variants were al
