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Informal settlements often appear chaotic, seeming perhaps to have emerged without any planning. Evidence suggests however that many slum areas are in fact the result of organized, structured processes carried out with discipline and precision. Formal and informal settlements coexist parallel to one another without significant interaction, and governments and informal planners rarely understand ea
Introduction: No national recommendation for antibiotic prophylaxis for planned caesarean section in Sweden exists. Swedish delivery units have chosen different strategies. Some units routinely administer antibiotic prophylaxis to all women for whom a caesarean section is planned, while other units give prophylactic antibiotics to risk groups only. We took advantage of this “natural experiment” to
Objective: This retrospective, multicentre, observational study analysed patients who underwent endovascular repair for blunt traumatic aortic injury (BTAI) at four tertiary trauma referral centres over twenty years. It aimed to determine early and long term survival, to analyse aortic and device related complications, and to assess the re-intervention rate after endovascular repair for BTAI. Meth
Bioenergy is perceived to play a vital role in climate mitigation, transition to renewable energy consumption, energy security, and local and rural socio-economic development. However, exploiting renewable bioenergy resources may need to be more sustainable in the current predominant paradigm. In this study, we raise two broad research questions: (1) what are the significant challenges to the curr
The North Atlantic region is a key component of the climate system via large-scale atmosphere and ocean circulation. Climate field reconstructions can provide a long-term context for ongoing climate change and contribute to our understanding of climate dynamics, impact of external forcings, and act as references for model evaluation and baseline for natural variability. There are distinct differen
OBJECTIVE: To examine the predictive capability of a 1-h vs 2-h postload glucose value for cardiovascular morbidity and mortality.DESIGN: Prospective, population-based cohort study (Malmö Preventive Project) with subject inclusion 1974-1992.RESULTS: Median age was 48 (25th-75th percentile: 48-49) years and mean FBG 4.6 ± 0.6 mmol/L. FBG and 2-h postload BG did not independently predict cardiovascu
Comprehensive experimental data on the fatigue properties of extruded Al6082-T6 is used together with crystal plasticity simulations to investigate the microstructure and surface roughness influence on fatigue initiation. Thesurface roughness of the specimens used in the experiments was mapped with White Light Interferometry (WLI) and the location of the fatigue initiation sites was identified and
Objective/background: Mycotic aortic aneurysms are rare, life threatening, and complex. This nationwide study aimed to assess outcome after repair of mycotic thoracic aortic aneurysms (MTAAs). Methods: Patients treated in Sweden for MTAAs between 2000 and 2016 were identified in the Swedish vascular registry (2010–16) and local patient registries (2000–09). Primary outcome was survival, and second
OBJECTIVES: There is highly suggestive evidence for an effect of air pollution exposure on dementia-related outcomes, but evidence is not yet present to clearly pinpoint which pollutants are the probable causal agents. The aims of this study was to assess the longitudinal association between exposures of fine ambient particulate matter (PM2.5) from residential wood burning, and vehicle exhaust, wi
OBJECTIVE: This study examined the prevalence and correlates of physical violence and rape among female sex workers (FSWs) in Ethiopia.DESIGN: A cross-sectional study using respondent-driven sampling technique.SETTING: Eleven major towns in Ethiopia.PARTICIPANTS: 4900 FSWs.MAIN OUTCOME MEASURES: The prevalence of experiences of physical beating and rape.RESULTS: Among FSWs, 17.5% reported physical
Introduction: CAM2038 q1w (once weekly) and q4w (once monthly) are investigational buprenorphine subcutaneous (SC) formulations based on FluidCrystal® injection depot technology. These two drug products are being developed for opioid dependence treatment, with a target for once-weekly and once-monthly SC dosing. The rationale for developing two products with different dosing frequencies is that tr
Fuel cells produce low quantities of local emissions, if any, and are therefore one of the most promising alternatives to internal combustion engines as the main power source in future vehicles. It is likely that urban buses will be among the first commercial applications for fuel cells in vehicles. This is due to the fact that urban buses are highly visible for the public, they contribute signifi
BACKGROUND: Long commutes by car are stressful. Most research studying health effects of commuting have summarized cross-sectional data for large regions. This study investigated whether the levels of stress and individual characteristics among 30–60 min car commuters were similar across different places within the county of Scania, Sweden, and if there were changes over time. METHODS: The study p
Long-term stability of endosseous implants depends on successful bone formation, ingrowth and adaptation to the implant. Specifically, it will define the mechanical properties of the newly formed bone-implant interface. 3D imaging during mechanical loading tests (in situ loading) can improve the understanding of the local processes leading to bone damage and failure. In this study, titanium screws
Background: Recently, the block-sequential regularized expectation maximization (BSREM) reconstruction algorithm was commercially introduced (Q.Clear, GE Healthcare, Milwaukee, WI, USA). However, the combination of noise-penalizing factor (β), acquisition time, and administered activity for optimal image quality has not been established for
Water scarcity is a consequence of complex interactions between water access and water use. In fact, the time period over which precipitation deficit accumulates is a determing factor for the occurrence of drought. Drought induces crop production losses and far-reaching societal effects. In the South American Altiplano, drought is a major hazard. Here, drought leads to food shortages, malnutrition
Background: Prostate-specific membrane antigen (PSMA) radiotracers such as [18F]PSMA-1007 used with positron emission tomography-computed tomography (PET-CT) is promising for initial staging and detection of recurrent disease in prostate cancer patients. The block-sequential regularization expectation maximization algorithm (BSREM) is a new PET reconstruction algorithm, which provides higher image
The present-day ocean-climate system configuration took shape during the Miocene Epoch. Toward the end of the epoch, in the late Tortonian at ca. 8.5 Ma, there was an exceptional event: collisional disruption of an >150-km-diameter asteroid, which created the Veritas family of asteroids in the asteroid belt. This event increased the flux of interplanetary dust particles rich in 3He to Earth and pr
Background: Perfluoroalkyl substances (PFAS) are widespread synthetic substances with various adverse health effects. A potential mechanism of toxicity for PFAS is via epigenetic changes, such as DNA methylation. However, few studies have evaluated associations between PFAS exposure and DNA methylation among adults, and data is especially scarce for women. Furthermore, exposure to environmental po
Background: Steroid injections are used in idiopathic carpal tunnel syndrome (CTS), but evidence of efficacy beyond 1 month is lacking. Objective: To assess the efficacy of local methylprednisolone injections in CTS. Design: Randomized, placebo-controlled trial. (ClinicalTrials.gov: NCT00806871) Setting: Regional referral orthopedic department in Sweden. Patients: Patients aged 18 to 70 years with
