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l-DOPA is the most commonly used treatment for symptomatic control in patients with Parkinson's disease. Unfortunately, most patients develop severe side-effects, such as dyskinesia, upon chronic l-DOPA treatment. The patophysiology of dyskinesia is unclear; however, involvement of serotonergic nerve fibers in converting l-DOPA to dopamine has been suggested. Therefore, potassium-evoked dopamine r
An experimental study has been carried out to investigate the effects of Coriolis force and centrifugal buoyancy force on convective heat transfer in a smooth cooling channel under rotating condition in a new rotation facility. The main motivation behind this work is to obtain required data for developing heat transfer correlations based on rotating state. In accordance with the open literature, f
The purpose of this article is to analyse quality attributes of regional public transport and their influence on modal choice, demand, and customer satisfaction through a literature review. The review is based on a working definition of regional public transport with boundaries toward local as well as interregional public transport: Regional public transport (i) targets passengers travelling betwe
One of the most well-known facts about unit root testing in time series is that the Dickey--Fuller (DF) test based on OLS demeaned data suffers from low power, and that the use of GLS demeaning can lead to substantial power gains. Of course, this development has not gone unnoticed in the panel unit root literature. However, while the potential of using GLS demeaning is widely recognized, oddly eno
This paper investigates the effect of the presence of a rib on the end-wall heat transfer of an obstacle by liquid crystal thermography. An obstacle with a rectangular cross section is placed in a rectangular channel and blocks the entire height of it (AR = 4). A rib with a square cross section is placed at two positions, i.e., in the upstream and downstream areas of the obstacle, respectively. An
OBJECTIVES: To investigate the reliability of a combined strategy of clinical assessment score followed by a local D-dimer test to exclude deep vein thrombosis. For comparison D-dimer was analysed post hoc and batchwise at a coagulation laboratory. DESIGN: Prospective multicenter management study. SETTING: Seven hospitals in southern Sweden. SUBJECTS: 357 patients with a suspected first episode of
Objective. The aim of this study was to present the outcome of patients treated with salvage cryotherapy after radiotherapy for prostate cancer at one institution. Materials and methods. Consecutive patients treated between 2007 and 2013 with transperineal cryotherapy for biopsy-verified local recurrence after radiotherapy were investigated. An external reviewer retrieved outcome data retrospectiv
PURPOSE: Adjuvant radiotherapy has during the past decades become increasingly used in the treatment of localized soft tissue sarcoma. We evaluated the effect of radiotherapy (RT) on local recurrence rates (LRRs) in Scandinavia between 1986 and 2005. METHODS AND MATERIALS: A total of 1,093 adult patients with extremity or trunk wall soft tissue sarcoma treated at four Scandinavian sarcoma centers
Objective. To examine the strategies that general dental practitioners (GDPs) use to administer antibiotic prophylaxis and to study the agreement between the administration strategies of GDPs and local recommendations. Methods. Postal questionnaires in combination with telephone interviews were used. Two hundred GDPs in two Swedish counties, Skane and Orebro, were asked to participate. The respons
We reviewed results of SBRT treatment of 138 patients with medically inoperable stage I NSCLC treated during 1996 - 2003 at five different centres in Sweden and Denmark. Mean age was 74 years ( range 56 - 90) with 69 men and 72 women. SBRT was delivered using a 3D conformal multifield technique and a stereotactic body frame. Doses delivered were 30 - 48 Gy (65% isodose at the periphery of planning
Correct reproductive timing is crucial for fitness. Breeding phenology even in similar species can differ due to different selective pressures on the timing of reproduction. These selection pressures define species' responses to warming springs. The temporal match-mismatch hypothesis suggests that timing of breeding in animals is selected to match with food availability (synchrony). Alternatively,
We have a limited amount of greenhouse gases left to emit, our global carbon budget, if we are to divert the worst effects of the climate crisis. This study aimed to map how municipalities implement carbon-budgeting in their efforts to fulfil the Paris agreement, and investigate why the instrument is not more frequently used. A survey among Swedish municipalities was carried out, in two stages. A
The aim of this study was to analyze if soya framing would be nationally-economical to produce with a vertical hydroponic system, compared to being imported from Brazil. With the intention to study the production cost and climate impact effects of local production. The costs and benefits of the culture have been analyzed and compared to imported soya from Brazil. In order to answer the questions o
In the last few years there has been an ongoing debate concerning the methods of assessing the quality of public libraries and their services. This study investigates the opinions and needs of the users at four different public libraries in Malm : the local libraries in Bellevueg rden, Limhamn, and Kirseberg, and the main library in central Malm . The purpose was to find out whether different user
Background: Neuropeptides, such as substance P (SP), have long been seen as mediators of widespread continuous airway inflammation, a process known as neurogenic inflammation. However, this has been difficult to demonstrate clinically, suggesting an alternative role for these signaling molecules. Objectives: We sought to examine the role of SP in nasal infection by assessing the release of SP in r
In 1947 the municipalities in Sweden received the monopoly to decide on and plan their land. Despite this, over 80 percent of the municipalities in Sweden say they experience lack of housing today. This thesis applies The Homevoter Hypothesis introduced by William A. Fischel in 2001 to try to explain why some municipalities are not able to construct enough housing for their inhabitants. The hypoth
Decentralization has in recent decades become a common concept in public policy making especially in developing countries. The concept, defined here as the transfer of functions, responsibilities and financial resources to lower levels of government, is further expected to have a positive effect on a country´s development process by reducing the inefficiency associated with a centralized form of g
CVD and cancer are the two leading causes of death worldwide. Improvement in cancer early detection and treatment has resulted in an increased number of cancer survivors. However, many of the survivors tend to develop CVD often leading to their demise. Conversely, people with pre-existing CVD conditions, especially the elderly, have increased chances of developing cancer and dying from the same. T
Purpose: This work proposes an accurate method for simulating dose reduction in digital mammography starting from a clinical image acquired with a standard dose. Methods: The method developed in this work consists of scaling a mammogram acquired at the standard radiation dose and adding signal-dependent noise. The algorithm accounts for specific issues relevant in digital mammography images, such
