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OBJECTIVES: To investigate exposure-response relationships between measured movements and postures of the wrist and the incidence of carpal tunnel syndrome (CTS), and any modifications by sex.METHODS: In 2011, we established a historical cohort of 9364 members of the Painters' Union in Denmark. Self-reported task distributions were obtained by questionnaire (53% responded) and combined with sex-sp
OBJECTIVES: Deficits in cognitive function remain prevalent in HIV-infected individuals. The aim of this European multicentre study was to assess factors associated with cognitive function in antiretroviral therapy (ART)-naïve HIV-infected subjects at the time of enrolment in the NEAT 001/Agence Nationale de Recherche sur le SIDA (ANRS) 143 study.METHODS: Prior to starting ART, seven cognitive tes
This thesis studies how subject extractions are accepted in Scandinavian (Danish, Norwegian, Swedish and Fenno-Swedish) through an extensive acceptability judgment study. The results from the study were compared with previous research and analyzed against accounts on why subject extraction constraints occur and why the acceptance of subject extractions in Scandinavian vasty varies. The subject ext
The ability to evaluate the geothermal potential at a depth of five to six kilometres in the crystalline bedrock is crucial for the EGS-technology to be utilized in the future. This work focuses primarily on presenting expected geological conditions at great depths in southwestern Scania. The study is based on information from E.ON’s deep drilling FFC-1 in Malmö and data and investigations of the
Background: NOTCH1 PEST domain mutations in chronic lymphocytic leukemia have recently been shown to be of prognostic relevance. Both NOTCH1 and NOTCH2 are constitutively activated in B-cell CLL but not expressed in normal B cells and may be involved in survival and resistance to apoptosis in CLL. We screened for mutations in different parts of both NOTCH1 and NOTCH2 genes and related the changes
This study employs large-scale Chinese pre-trained language models (BERT series) and the Fill-Mask Association Test (FMAT) to systematically measure gender- and age-based, as well as class-based, heterogeneity in marital status stereotypes embedded in natural language. Four sub-studies were designed to examine the effects of age (22–40 years), residence (urban vs. rural), and education (high vs. l
In the rapidly evolving landscape of entrepreneurship, Artificial Intelligence (AI) has emerged as a pivotal tool reshaping how founders navigate uncertainty and allocate resources. Grounded in Sarasvathy’s dual logics of causation (predictive, goal-oriented planning) and effectuation (adaptive, resource-driven experimentation), this study investigates whether AI reinforces entrepreneurs’ default
Understanding how sympatric species partition resources is critical for biodiversity conservation, particularly in vulnerable ecosystems. As Arctic ecosystems undergo rapid climate change, understanding how animals use space and select habitats becomes essential for effective conservation planning. Advances in technologies can now provide high-resolution data on species movements and habitat use,
Ready-to-eat (RTE) leafy greens are popular products that unfortunately have been associated with numerous foodborne illness outbreaks. Since the influence of consumer practices is essential for their quality and safety, the objective of this study was to analyze the microbiota of RTE products throughout shelf life during simulated household conditions. Products from different companies were analy
Background: Depression in the elderly population has been identified as a significant public health problem associated with adverse outcomes such as decreased quality of life, cognitive decline, and increased rates of suicide. We aimed to determine the prevalence and factors associated with depressive symptoms among geriatric population in Moshi district council, northern Tanzania. Methods: This c
Through a systematic review and a series of meta-analyses, we evaluated the general responsiveness of putative transcriptional biomarkers of general toxicity and chemical stress. We targeted metal exposures performed on bivalves under controlled laboratory conditions, and selected six transcripts associated with general toxicity for evaluation: catalase (cat), glutathione-S-transferase (gst), heat
Postural orthostatic tachycardia syndrome (POTS) is a cardiovascular autonomic disorder characterized by excessive heart rate increase on standing, leading to debilitating symptoms with limited therapeutic possibilities. Proteomics is a large-scale study of proteins that enables a systematic unbiased view on disease and health, allowing stratification of patients based on their protein background.
Understanding how and why soil microbial communities respond to temperature changes is important for understanding the drivers of microbial distribution and abundance. Studying soil microbe responses to warming is often made difficult by concurrent warming effects on soil and vegetation and by a limited number of warming levels preventing the detection of non-linear effects. A unique area in Icela
Objective: Recent research in knee osteoarthritis (OA) highlights the role of the meniscus in OA pathology. Our aim was to compare the proteomes of medial and lateral menisci from end-stage medial compartment knee OA patients, with reference menisci from knee-healthy deceased donors, using mass spectrometry. Design: Tissue plugs of Ø3 mm were obtained from the posterior horns of the lateral and me
Thicker snowpacks and their insulation effects cause winter‐warming and invoke thaw of permafrost ecosystems. Temperature‐dependent decomposition of previously frozen carbon (C) is currently considered one of the strongest feedbacks between the Arctic and the climate system, but the direction and magnitude of the net C balance remains uncertain. This is because winter effects are rarely integrated
Context. Extremely metal-poor (EMP) stars preserve a fossil record of the composition of the ISM when the Galaxy formed. It is crucial, however, to verify whether internal mixing has modified their surface composition, especially in the giants where most elements can be studied. Aims. We aim to understand the CNO abundance variations found in some, but not all EMP field giants analysed earlier. Mi
Purpose: Transcriptional pathway activity and the molecular subtypes of breast cancer metastases have been shown to significantly influence patient postrelapse survival. Here, we further determine the relevance of clinically employed gene signatures in the advanced breast cancer (ABC) setting. Experimental Design: Sufficient RNA for expression profiling was obtained from distant metastatic or inop
I detta examensarbete, som skrivits i samarbete med Svenska Turistföreningen (STF), beräknas och utvärderas de växthusgasutsläpp som driften av föreningens fjällstugor, belägna i väglöst land, ger upphov till. Beräkningarna baseras på de fyra fjällstugorna Alesjaure, Sälka, Kårsavagge och Nallo. I studien beräknas det att en gästnatt, det vill säga en övernattning av en person, på en av de studeraThis master thesis was written in collaboration with the Swedish Tourist Association and evaluates the yearly greenhouse gas emissions caused by the management of the association’s mountain huts. The hut’s are situated in roadless land. The calculations are based on the four mountain huts Alesjaure, Sälka, Kårsavagge and Nallo. An overnight stay at one of the studied mountain huts give rise to on
A robot should follow a given path as accurately as possible. There are however almost always deviations from the desired path, and when the deviations become too large it may be a problem. Some of the deviations stem from transmissions of the robot, and the deviations become more pronounced when there are process forces and gravitational forces present, that affect the transmissions. When positio
