Filtyp
Proton Beam Therapy (PBT) is an increasingly utilised modality for treating tumours by utilising the physical properties of accelerated proton beams. This review explores the development of PBT, its dosimetric advantages over conventional x-ray-based radiotherapy, and the rationale behind its use in paediatric oncology whilst simultaneously considering the various challenges associated with its de
Popular Abstract in English Proteins are a big biological molecules that help cells to function. Proteins play important roles in all vital processes of the living cell, transporting molecules, speeding up chemical reactions, supporting structure of other proteins and the cell, helping the cell to move. Various disease-causing agents (e.g. bacteria and viruses) are constant threat to us. It is thMost drugs act on biomacromolecules. The Cost of developing new drugs is very high. A method to accurately predict binding affinities would be very useful. We have studied molecular mechanics with generalised Born and surface--area solvation (MM/GBSA) and alchemical free energy perturbation methods (FEP) for use in calculations of ligand binding energies. For the MM/GBSA method we have tested: Ca
We have studied the convergence of QM/MM calculations with respect to the size of the QM system. We study a proton transfer between a first-sphere cysteine ligand and a second-sphere histidine group in [Ni,Fe] hydrogenase and use a 446-atom model of the protein, treated purely with QM methods as a reference. We have tested 12 different ways to redistribute charges close to the junctions (to avoid
Human carbonyl reductase 1 (CBR1), that is one of the enzymes responsible for the reduced efficiency of treatments by the antineoplastic agents anthracyclines, was functionally expressed in Saccharomyces cerevisiae. CBR1 was purified and kinetically characterised using daunorubicin as substrate. CBR1-catalysed reduction of daunorubicin followed an apparent Michaelis-Menten kinetics with K-M = 85.2
Abstract Author: Dilan Demircioglu Title: The best interst of the child comes first Supervisor: Anders Lundberg The intention of this essay was to investigate and gain understanding on how social-workers work with unaccompanied children, with the aim of what is considered in the best interest of the child. What is considered being the best inters of the child child has many different contexts, an
In recent years, hydrogels have been demonstrated as simple and cheap additives to improve the optical properties and material stability of organometal halide perovskites (OHPs), with most research centered on the use of hydrophilic, petrochemical-derived polymers. Here, we investigate the role of a peptide hydrogel in passivating defect sites and improving the stability of methylammonium lead iod
Over the past few decades, the automotive industry has increasingly looked towards increasing the efficiency of the internal combustion engine to meet more stringent emission norms and as a measure to meet demands for improved air quality in cities. One method to improve the internal combustion engine efficiency is to recover some of the energy lost to the coolant and the exhaust using a secondary
Enzymes of the xanthine oxidase family are among the best characterized mononuclear molybdenum enzymes. Open questions about their mechanism of transfer of an oxygen atom to the substrate remain. The enzymes share a molybdenum cofactor (Moco) with the metal ion binding a molybdopterin (MPT) molecule via its dithiolene function and terminal sulfur and oxygen groups. For xanthine dehydrogenase (XDH)
Abstract. This study presents a comprehensive assessment of the meteorological conditions and atmospheric flow during the Lagrangian-type "Hill Cap Cloud Thuringia 2010" experiment (HCCT-2010), which was performed in September and October 2010 at Mt. Schmücke in the Thuringian Forest, Germany and which used observations at three measurement sites (upwind, in-cloud, and downwind) to study physical
Designing stem-cell-based dopamine cell replacement trials for Parkinson’s disease Perspective https://doi.org/10.1038/s41591-019-0507-2 1John van Geest Centre for Brain Repair, Department of Clinical Neurosciences and WT-MRC Cambridge Stem Cell Institute, University of Cambridge, Cambridge, UK. 2John van Geest Centre for Brain Repair, Cambridge University, Cambridge, UK. 3A full list of members a
https://www.regenerative-neurobiology.lu.se/sites/regenerative-neurobiology.lu.se/files/designing_stem-cell-based.pdf - 2026-07-19
Övningshandledning för fältarbetsvecka på Österlen, NGE501 EX-guide NGEA01/JÅ/2017 1 Excursion guide NW Skåne, NGEA 01 Ht 2017 PART 2 Description of the STOPS By Associate prof. Jonas Åkerman EX-guide NGEA01/JÅ/2017 2 Contents Innehåll PART 2 STOPS .......................................................................................................................................................
https://www.nateko.lu.se/sites/nateko.lu.se/files/nwpart2.pdf - 2026-07-19
Brevmall Revised 260529 TR Information to Supervisors of Master´s Thesis Projects in Molecular Biology The Master´s thesis project is one of the most important and valuable courses that our students take during their education. Therefore, we very much appreciate the support and mentorship that you, any co-supervisors, and other members of your research team will provide throughout the different st
Med ic inska fakulte tens kans l i Handlingsplan för att förebygga och hantera konflikter mellan handledare och doktorand INTRODUKTION Under forskarutbildningen kan det uppstå meningsskiljaktigheter mellan handledare och doktorand. Ibland kan sådana utvecklas till konflikter som i värsta fall kan bli infekterade och få negativa konskevenser för såväl doktorand, handledare som projekt. Det är därfö
https://www.intramed.lu.se/sites/intramed.lu.se/files/2023-02/Handlingsplan_konflikt_doktorand_handledare_2017.pdf - 2026-07-19
Gentypning av njurtumör hos barn ger bättre behandling – Vetenskap och Hälsa Hoppa till innehåll Vetenskap och hälsa Populärvetenskapligt om medicinsk forskning i Skåne Teman Podd Tidskrift Prenumerera Om webbplatsen Kontakt Sök Sök Gentypning av njurtumör hos barn ger bättre behandling 2016-01-07 ⚠️ Den här artikeln är mer än 5 år gammal. Nya forskningsrön kan ha tillkommit. Den vanligaste formen
https://www.vetenskaphalsa.se/gentypning-av-njurtumor-hos-barn-ger-battre-behandling/ - 2026-07-19
NRCF – Nationellt resurscentrum för fysik Fysik: Gy11 och Gy25 1 Sammanställning: Ämnesplan för Fysik (Gy11) och ämnesplaner för Fysik och Fysik – fördjupning (Gy25) GY11 (reviderad 2022) GY25 Ämne - Fysik Fysik är ett naturvetenskapligt ämne som har sitt ursprung i människans behov av att förstå och förklara sin omvärld. Fysik behandlar allt från växelverkan mellan materiens minsta beståndsdelar
https://www.nrcf.lu.se/sites/nrcf.lu.se/files/2024-05/Fysik_A%CC%88mnesplaner_Gy11vsGy25_0.pdf - 2026-07-19
Analytics for students Short instructions to the new ”Analytics” tab in QPS In the left cloumn you find the new tab ”Analytics”. If you click on this you will see all your data collected from the entire programme. Please observe that the data shown in these views is exported from the QPS system once a day and therefore you will not be able to see new data immediately. All tables and figures that a
https://www.qps.education.lu.se/sites/qps.education.lu.se/files/2022-10/QPS%20-%20Analytics%20for%20students.pdf - 2026-07-19
PFOS (Perfluoroktansulfonat) har genom sina unika ytaktiva och beständiga egenskaper använts i en mängd olika tillämpningar och blivit ett av jordens mest spridda ämnen. Metallytbehandling, hydrauloljor till flygplan och impregnering av textilier hör till ämnets användningsområden, men mest uppmärksammat är nog tillsatsen till brandsläckningsskum där PFOS är den aktiva beståndsdelen. Upprepade släPFOS (Perfluorooctane sulfonate) has, through its unique surface active and non-reactive properties been used in a range of applications and has become one of the earth’s most wide spread substances. Metal plating, hydraulic fluids and textile repellants are among the chemical’s field of application, but most attention has probably been given the presence in fire-fighting foam, where PFOS constitu
