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This article discusses the advantages of the the Coherence Based Genealogical Method (CBGM), not only as a tool for reconstructing the text of the New Testament, but also for surveying the history of readings and for explaining textual changes. The CBGM promises to detect readings, which have emerged several times independently in the textual tradition. The method is applied to selected examples i

We have estimated affinities for the binding of 34 ligands to trypsin and nine guest molecules to three different hosts in the SAMPL3 blind challenge, using the MM/PBSA, MM/GBSA, LIE, continuum LIE, and Glide score methods. For the trypsin challenge, none of the methods were able to accurately predict the experimental results. For the MM/GB(PB)SA and LIE methods, the rankings were essentially rand

Three dimensional domain swapping is one of the mechanisms involved in formation of insoluble aggregates of some amyloidogenic proteins. It has been proposed that proteins able to swap domains may share some common structural elements like conformationally constrained flexible turns/loops. We studied the role of loop L1 in the dimerization of human cystatin C using mutational analysis. Introductio

The decays of the high angular momentum, high spin F-4(0) states of the electron configuration 3s3p3d in aluminium-like ions (with three electrons outside a closed shell) have been identified in delayed spectra of foil excited Ti, Fe and Ni ion beams. The line identifications were aided by HXR, MCHF, and MCDF calculations and are corroborated by lifetime measurements which demonstrate the differen

We studied electrophysiological properties of single chemosensory neurons in the mouthparts of the spiny lobsters Panulirus argus and Panulirus interruptus to complement our growing understanding of the behavioral roles of mouthparts of decapod crustaceans. Food mixtures and 13 single compounds were used to characterize the response specificity, sensitivity, and time course of individual neurons i

From the end of the 18th century, agriculture in Sweden changed dramatically due to enclosures in the parishes with freeholders. In the parishes with noble tenants, land was instead redistributed according to a manorial landlords’ decision. The first aim of this paper is to analyze the impact of the enclosure movements on social differentiation. The second aim of this paper is to compare the socia

Inter-firm contractual arrangements characteristically form the back-bone of a business relationship, and are facilitated by a mix of informal and formal governance structures. In the lead-up to and post WTO accession, the Chinese government implemented wide-ranging reforms to its business environment. As a result, the use of inter-firm contracts as a business norm has been influenced by legislati

The thesis explores to which extent it is possible for an individual to live in accordance with his or her chosen gender identity within the framework of the European Convention on Human Rights, and within the conventional right to privacy in particular. The specific research question has been to find out whether a right to decide one's gender identity has emerged in the European Court of Huma

The EC provisions on fiscal State aid have since 1997 become an important part of the work against harmful tax competition. The application of the State aid rules to harmful measures is a reversal of the common direction of aid (i.e. leading to preferential tax treatment). This creates several interest-ing legal problems, for example if these rules provide a suitable method to tackle harmful tax c

Using qualitative interviews with twenty recent graduates, this study explores how participants understand and experience career in the aftermath of the crisis. Overall, this study suggests that several dominant theories and practical storylines surrounding notions of career and career development present a static view that fails to take important contexts into account. We aim to provide a deeper

In patients with radiculopathy due to degenerative disease in the cervical spine, surgical outcome is still presenting with moderate results. The preoperative investigations consist of clinical investigation, careful history and most often magnetic resonance imaging (MRI) of the cervical spine. When MRI shows multilevel degeneration, different strategies are used for indicating which nerve root/ro

Pollen productivity estimates (PPE) are one of the critical parameters for a quantitative reconstruction of past vegetation from fossil pollen records. Modern pollen and vegetation data were collected in traditional landscapes of southern Sweden to derive PPE for the most characteristic plant taxa. The 42 selected sites are assumed to be good analogues of historical to prehistorical grasslands. A

TNP-470, a semisynthetic derivative of fumagillin, is an acknowledged angiogenesis inhibitor, presently undergoing clinical trials. It exerts an anti-proliferative effect directed against endothelial cells. This effect is known to be based on cell cycle inhibition effected by the p53/p21 pathway. We observed short-term toxicity of TNP-470 in the B16F10 murine melanoma cell line in vitro and invest

The diurnal and vertical variability of heat and carbon dioxide (CO2) in the atmospheric surface layer are studied by analyzing measurements from a 213 m tower in Cabauw (Netherlands). Observations of thermodynamic variables and CO2 mixing ratio as well as vertical profiles of the turbulent fluxes are used to retrieve the contribution of the budget terms in the scalar conservation equation. On the

The effects of intravenously infused calcitonin gene-related peptide (CGRP) on the regional blood flow of the cochlea, the middle ear and the upper respiratory tract were studied. Two series of experiments were performed without pretreatment on either conscious or pentobarbital anaesthetized animals; in one series the cervical sympathetic chain was severed on one side; in another series anaestheti

Certification programmes in fisheries have been introduced as a market-based tool for promoting sustainable fishing practices. While consumers appreciate the eco-labels by paying a price premium in the retail market, there is not much research on whether the premium transmits to the fishing industry. This paper adds to the literature by studying price premiums at port for the Swedish Baltic Sea co

Background: Spironucleus salmonicida is an anaerobic parasite that can cause systemic infections in Atlantic salmon. Unlike other diplomonad parasites, such as the human pathogen Giardia intestinalis, Spironucleus species can infiltrate the blood stream of their hosts eventually colonizing organs, skin and gills. How this presumed anaerobe can persist and invade oxygenated tissues, despite having